Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Violetta N. Pivtoraiko"'
Autor:
Violetta N. Pivtoraiko, Tamara Racic, Eric E. Abrahamson, Victor L. Villemagne, Benjamin L. Handen, Ira T. Lott, Elizabeth Head, Milos D. Ikonomovic
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Individuals with Down syndrome (DS) have a genetic predisposition for amyloid-β (Aβ) overproduction and earlier onset of Aβ deposits compared to patients with sporadic late-onset Alzheimer’s disease (AD). Positron emission tomography (PET) with
Externí odkaz:
https://doaj.org/article/dd692ebe3f2b459687b02f367a106ae7
Autor:
Vitaly A Selivanov, Tatyana V Votyakova, Violetta N Pivtoraiko, Jennifer Zeak, Tatiana Sukhomlin, Massimo Trucco, Josep Roca, Marta Cascante
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 3, p e1001115 (2011)
Reactive oxygen species (ROS) produced in the mitochondrial respiratory chain (RC) are primary signals that modulate cellular adaptation to environment, and are also destructive factors that damage cells under the conditions of hypoxia/reoxygenation
Externí odkaz:
https://doaj.org/article/e46d90fe41af4a36ab5ae3fbecd6f951
Autor:
William E. Klunk, Elliott J. Mufson, Manik L. Debnath, Milos D. Ikonomovic, Chester A. Mathis, Eric E. Abrahamson, Violetta N. Pivtoraiko, William R. Paljug
Publikováno v:
Alzheimer's & Dementia. 15:P302-P302
Autor:
Kevin A. Roth, Barbara J. Klocke, Violetta N. Pivtoraiko, Burton J. Mader, Hilary M Flippo, John J. Shacka, Leandra R. Mangieri
Publikováno v:
ACS Chemical Neuroscience. 3:1063-1072
Rotenone, which selectively inhibits mitochondrial complex I, induces oxidative stress, α-synuclein accumulation, and dopaminergic neuron death, principal pathological features of Parkinson's disease. The autophagy-lysosome pathway degrades damaged
Autor:
Violetta N. Pivtoraiko, Kevin A. Roth
Publikováno v:
Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, Second Edition
Autor:
Elliott J. Mufson, Milos D. Ikonomovic, Violetta N. Pivtoraiko, Steven T. DeKosky, Sue Leurgans, Eric E. Abrahamson
Posterior cingulate cortex (PCC) accumulates amyloid-β (Aβ) early in Alzheimer's disease (AD). The relative concentrations of full-length Aβ and truncated, pyroglutamate-modified Aβ (NpE3) forms, and their correlations to cognitive dysfunction in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5009122f86f571d87d2464615a263b
https://europepmc.org/articles/PMC4268150/
https://europepmc.org/articles/PMC4268150/
Autor:
Marta Cascante, Vitaly A. Selivanov, Josep Roca, Violetta N. Pivtoraiko, Tatyana V. Votyakova, Tatiana Sukhomlin, Massimo Trucco, Jennifer A. Zeak
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 3, p e1001115 (2011)
PLoS Computational Biology; Vol 7
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS Computational Biology
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS Computational Biology; Vol 7
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS Computational Biology
Dipòsit Digital de la UB
Universidad de Barcelona
Reactive oxygen species (ROS) produced in the mitochondrial respiratory chain (RC) are primary signals that modulate cellular adaptation to environment, and are also destructive factors that damage cells under the conditions of hypoxia/reoxygenation
Autor:
Kevin A. Roth, John J. Shacka, Burton J. Mader, Violetta N. Pivtoraiko, Guy A. Caldwell, Kim A. Caldwell, Adam J. Harrington, Austin Luker
Publikováno v:
Journal of Neurochemistry.
We have shown previously that the plecomacrolide antibiotics bafilomycin A1 and B1 significantly attenuate cerebellar granule neuron death resulting from agents that disrupt lysosome function. To further characterize bafilomycin-mediated cytoprotecti
Publikováno v:
The FASEB Journal. 23
Publikováno v:
Antioxidantsredox signaling. 11(3)
Lysosomes critically regulate the pH-dependent catabolism of extracellular and intracellular macromolecules delivered from the endocytic/heterophagy and autophagy pathways, respectively. The importance of lysosomes to cell survival is underscored not