Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Violetta Krajka-Kuzniak"'
Autor:
Andrzej Nowicki, Paulina Skupin-Mrugalska, Malgorzata Jozkowiak, Marcin Wierzchowski, Marcin Rucinski, Piotr Ramlau, Violetta Krajka-Kuzniak, Jadwiga Jodynis-Liebert, Hanna Piotrowska-Kempisty
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1100 (2020)
Targeting tumor cell motility and proliferation is an extremely important challenge in the prevention of metastasis and improving the effectiveness of cancer treatment. We recently published data revealing that DMU-214, the metabolite of firmly cytot
Externí odkaz:
https://doaj.org/article/5a225fdb5baf45f19276e0b2009e02c6
Publikováno v:
Cancer Research. 82:106-106
Pancreatic cancer is characterized by constitutive activation of mitogen-activated protein kinases (MAPKs) like JNK and p38 determining its malignant phenotypes. Overexpression of NF-κB and COX-2 involved in inflammation contributes to increased cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2565b95b24090d6ac49857cb1da69de
https://doi.org/10.1158/1538-7445.am2022-106
https://doi.org/10.1158/1538-7445.am2022-106
Autor:
Katarzyna Papierska, Eliza Judasz, Wiktoria Tonińska, Maciej Kubicki, Violetta Krajka-Kuźniak
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10739 (2024)
Our previous studies demonstrated the modulatory effects of new synthetic thio-chalcone derivatives in dishes on the Nrf2, NF-κB, and STAT3 signaling pathways in colon cancer cells. This study aimed to evaluate the effect of four selected active cha
Externí odkaz:
https://doaj.org/article/1f95842bb99a4311bfe1dce3939ce2a9
Autor:
Marcin Rucinski, Hanna Piotrowska-Kempisty, Małgorzata Józkowiak, Piotr Ramlau, Paulina Skupin-Mrugalska, Andrzej Nowicki, Violetta Krajka-Kuzniak, Marcin Wierzchowski, Jadwiga Jodynis-Liebert
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1100 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 3
International Journal of Molecular Sciences
Volume 21
Issue 3
Targeting tumor cell motility and proliferation is an extremely important challenge in the prevention of metastasis and improving the effectiveness of cancer treatment. We recently published data revealing that DMU-214, the metabolite of firmly cytot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d866d63f143775bdfe8c505d4b30f7ad
https://www.mdpi.com/1422-0067/21/3/1100
https://www.mdpi.com/1422-0067/21/3/1100
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9579-9592 (2023)
The dysregulation of energetic metabolism is one of the hallmarks of cancer cells. Indeed, the growth of head and neck squamous cell carcinoma (HNSCC) cells depends heavily on glycolytic activity, which can be considered a potential therapeutic targe
Externí odkaz:
https://doaj.org/article/593f29a714c14918b20e17fe03f577a4
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 2, Pp 207-217 (2023)
Glioblastoma multiforme (GBM), a high-grade astrocytoma, is an incurable brain tumor associated with genetic heterogeneity and dysregulated signaling pathways. As alternations of the endocannabinoid system have been demonstrated in GBM cells, the sub
Externí odkaz:
https://doaj.org/article/2ca2d7f97aea40c296d996c72be8658f
Autor:
Anna Paszel-Jaworska, Justyna Gornowicz-Porowska, Aleksandra Dańczak-Pazdrowska, Adriana Polańska, Violetta Krajka-Kuźniak, Maciej Stawny, Aleksandra Gostyńska, Michał Masternak, Błażej Rubiś
Publikováno v:
Journal of Medical Science, Vol 92, Iss 3 (2023)
Senescence is accompanied by numerous processes that lead to alterations in cell metabolism, cell cycle arrest, and, increased production and secretion of senescence-associated secretory phenotype (SASP). Consequently, signaling pathways cascades are
Externí odkaz:
https://doaj.org/article/d6266b5fc02744ad959e18f5015dc1dd
Autor:
Katarzyna Papierska, Violetta Krajka-Kuźniak, Robert Kleszcz, Tomasz Stefański, Rafał Kurczab, Maciej Kubicki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract This study aimed to synthesize new thioderivative chalcones and analyze their impact on the NF-κB, STAT3, EGFR and Nrf2 signaling pathways in colorectal cancer cells. Among the studied compounds, derivatives 4 and 5 decreased the activation
Externí odkaz:
https://doaj.org/article/04988c50eaaa478ea68e102117297c49
Publikováno v:
Journal of Medical Science, Vol 92, Iss 2 (2023)
Background. Several studies suggest that the pleiotropic properties of betanin may interfere with different signaling pathways. Our previous studies on human hepatocytes showed that betanin activated the nuclear factor erythroid-2-related factor 2 (N
Externí odkaz:
https://doaj.org/article/d3f71e25b0f34016948648d466e7a5f8
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2052 (2023)
The development and progression of cancer are associated with the dysregulation of multiple pathways involved in cell proliferation and survival, as well as dysfunction in redox balance, immune response, and inflammation. The master antioxidant pathw
Externí odkaz:
https://doaj.org/article/38d75fad1c044598ac6f2c9526a7942e