Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Violetta Kozik"'
Autor:
Andrzej Zieba, Violetta Kozik, Kinga Suwinska, Agata Kawulok, Tadeusz Pluta, Josef Jampilek, Andrzej Bak
Publikováno v:
Molecules, Vol 29, Iss 18, p 4337 (2024)
In this work, the synthesis, structural analysis and anticancer properties of 5-methyl-9-trifluoromethyl-12H-quino[3,4-b][1,4]benzothiazinium chloride (3) are described. Compound 3 was synthesized by reacting 1-methyl-4-butylthio-3-(benzoylthio)quino
Externí odkaz:
https://doaj.org/article/22651b7cc45e41409b49db1b92255026
Autor:
Ewa Kisiel-Nawrot, Dominika Pindjakova, Malgorzata Latocha, Andrzej Bak, Violetta Kozik, Kinga Suwinska, Alois Cizek, Josef Jampilek, Andrzej Zięba
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13250 (2023)
In this paper, we describe a new method for synthesizing hybrid combinations of 1,2,3-triazoles with a tetracyclic quinobenzothiazinium system. The developed approach allowed for the production of a series of new azaphenothiazine derivatives with the
Externí odkaz:
https://doaj.org/article/3e5689bdacbf47b49aced63207436486
Autor:
Andrzej Bak, Violetta Kozik, Aleksandra Swietlicka, Wojciech Baran, Adam Smolinski, Andrzej Zięba
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 984 (2023)
The multistep synthesis of novel bis-terephthalthioamides based on methyl esters of amino acids (AAs) was proposed using conventional heating and microwave-assisted approaches. In fact, the comparative case study on the thionation of new symmetrical
Externí odkaz:
https://doaj.org/article/5a5eb602a89c40128b34d02e03d63306
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11686 (2023)
The marketed drug Doxorubicin (DOX) and the promising anti-cancer agent 9-(N-piperazinyl)-5-methyl-12(H)-quino[3,4-b][1,4]benzothiazinium chloride (9-PBThACl) were used to prepare and compare a range of liposomal delivery systems based on dipalmitoyl
Externí odkaz:
https://doaj.org/article/b0fe47596974433ea92daa26edd2e7db
Autor:
Ewa Kisiel-Nawrot, Malgorzata Latocha, Andrzej Bak, Violetta Kozik, Josef Jampilek, Andrzej Zieba
Publikováno v:
Applied Sciences, Vol 13, Iss 5, p 2886 (2023)
The antitumor potency of a series of designed and prepared antibacterial quinobenzothiazines was evaluated against different types of human cancer cell lines, such as glioblastoma SNB-19, lung adenocarcinoma A549 and breast cancer T47D, and the activ
Externí odkaz:
https://doaj.org/article/14b5920b0ab74483ac3d97a4e583943f
Autor:
Andrzej Bak, Jiri Kos, Gilles Degotte, Aleksandra Swietlicka, Tomas Strharsky, Dominika Pindjakova, Tomas Gonec, Adam Smolinski, Pierre Francotte, Michel Frederich, Violetta Kozik, Josef Jampilek
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3611 (2023)
A series of seventeen 4-chlorocinnamanilides and seventeen 3,4-dichlorocinnamanilides were characterized for their antiplasmodial activity. In vitro screening on a chloroquine-sensitive strain of Plasmodium falciparum 3D7/MRA-102 highlighted that 23
Externí odkaz:
https://doaj.org/article/0dc5f882afc74f9d96aec6749923e6f1
Autor:
Ewa Kisiel-Nawrot, Dominika Pindjakova, Malgorzata Latocha, Andrzej Bak, Violetta Kozik, Kinga Suwinska, Aleksander Sochanik, Alois Cizek, Josef Jampilek, Andrzej Zięba
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15078 (2022)
A new method for modifying the structure of tetracyclic quinobenzothiazinium derivatives has been developed, allowing introduction of various substituents at different positions of the benzene ring. The method consists of reacting appropriate aniline
Externí odkaz:
https://doaj.org/article/a8f57133da314f2f8ebcf760ac769bd0
Autor:
Miloš Hricovíni, Raymond J. Owens, Andrzej Bak, Violetta Kozik, Witold Musiał, Roberta Pierattelli, Magdaléna Májeková, Yoel Rodríguez, Robert Musioł, Aneta Slodek, Pavel Štarha, Karina Piętak, Dagmara Słota, Wioletta Florkiewicz, Agnieszka Sobczak-Kupiec, Josef Jampílek
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14815 (2022)
The knowledge of interactions between different molecules is undoubtedly the driving force of all contemporary biomedical and biological sciences. Chemical biology/biological chemistry has become an important multidisciplinary bridge connecting the p
Externí odkaz:
https://doaj.org/article/07938b50517a4fa3a7c60607a99f9b1b
Publikováno v:
Materials, Vol 15, Iss 4, p 1586 (2022)
The aim of this study is to prepare a liposomal delivery system for 5-methyl-12 (H)-quino[3,4-b]-1,4-benzothiazine chloride (5-MBT) and study the in vitro release characteristics. The release of 5-MBT from a liposomal complex with human serum albumin
Externí odkaz:
https://doaj.org/article/285e7d2d4fd24105971899935d07ca11
Autor:
Anna Empel, Andrzej Bak, Violetta Kozik, Malgorzata Latocha, Alois Cizek, Josef Jampilek, Kinga Suwinska, Aleksander Sochanik, Andrzej Zieba
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12826 (2021)
A series of new tertiary phenothiazine derivatives containing a quinoline and a pyridine fragment was synthesized by the reaction of 1-methyl-3-benzoylthio-4-butylthioquinolinium chloride with 3-aminopyridine derivatives bearing various substituents
Externí odkaz:
https://doaj.org/article/06e5cd6dfe35423e96a070e02a335f1e