Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Violetta Klimek"'
Autor:
Issam Zineh, Robert Temple, Phillip V. Dinh, Sue-Jane Wang, Li Zhang, Mitchell V. Mathis, Cheri Y. Lindberg, Ellis F. Unger, Peiling Yang, Violetta Klimek, Robert L. Levin, Jee Eun Lee, Yaning Wang, Huixia Zhang, Linda Fossom, Atul Bhattaram, H. M. James Hung, Bei Yu, Thomas Laughren, Barry N. Rosloff, Jogarao V. S. Gobburu
Publikováno v:
The Journal of Clinical Psychiatry. 72:1166-1173
Objective Vilazodone was recently approved by the US Food and Drug Administration (FDA) for the treatment of major depressive disorder (MDD). The purpose of this review is to summarize the FDA's approach to its review of the clinical pharmacology and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e237951f77753f5ea98b78361403494
https://doi.org/10.4088/jcp.11r06984
https://doi.org/10.4088/jcp.11r06984
Autor:
Craig A. Stockmeier, Katalin Szebeni, Violetta Klimek, John Kalbfleisch, Lianbin Xiang, Gregory A. Ordway, Beata Karolewicz, Attila Szebeni
Publikováno v:
Brain Research. 1207:214-224
Previous findings from this laboratory demonstrating changes in dopamine (DA) transporter and D2 receptors in the amygdaloid complex of subjects with major depression indicate that disruption of dopamine neurotransmission to the amygdala may contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc88272473978730c5d1ae360fb5ee69
https://doi.org/10.1016/j.brainres.2008.02.009
https://doi.org/10.1016/j.brainres.2008.02.009
Autor:
Kate Szebeni, Shannon Orr, Geary S. Alford, Gregory A. Ordway, Violetta Klimek, John E. Piletz
Publikováno v:
Addictive Behaviors. 31:1503-1509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b356b414a8a21afe84aed3b422330e2
https://doi.org/10.1016/j.addbeh.2005.10.012
https://doi.org/10.1016/j.addbeh.2005.10.012
Autor:
Craig A. Stockmeier, Katalin Szebeni, Emily Nail, Laurel Johnson, Beata Karolewicz, He Zhu, Gregory A. Ordway, Violetta Klimek
Publikováno v:
Brain Research. 1043:57-64
Altered concentrations of dopamine transporter and D2/D3 receptors have been observed in the amygdaloid complex of subjects with major depression. These findings are suggestive of neurochemical abnormalities in the limbic dopamine system in depressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa43ebc18ad35977e1dabcc978d54ecd
https://doi.org/10.1016/j.brainres.2005.02.043
https://doi.org/10.1016/j.brainres.2005.02.043
Publikováno v:
Journal of Psychiatric Research. 37:387-397
Neurochemical imbalance between noradrenergic and serotonergic systems has been postulated to underlie the pathophysiology of psychiatric illnesses involving mood disorders. The present study was designed to examined the possibility that serotonergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e654624fa408de32b22935de7648bdd
https://doi.org/10.1016/s0022-3956(03)00045-1
https://doi.org/10.1016/s0022-3956(03)00045-1
Publikováno v:
Biological Psychiatry. 53:315-323
Background Recent postmortem studies demonstrate disrupted neurochemistry of the noradrenergic locus coeruleus (LC) in major depression (MD). Increased levels of tyrosine hydroxylase and decreased levels of norepinephrine transporter implicate a nore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc30eddb866795240d09da1ae4b993a
https://doi.org/10.1016/s0006-3223(02)01728-6
https://doi.org/10.1016/s0006-3223(02)01728-6
Autor:
Gregory A. Ordway, Violetta Klimek
Publikováno v:
CNS Spectrums. 6:697-703
In this paper, we review research utilizing postmortem brain tissue in order to investigate the potential neuropathology of the noradrenergic system in psychiatri disorders. The postmortem tissue approach to the study of the noradrenergic system has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2b2786bb54141a08bb7eb86a5d374c
https://doi.org/10.1017/s1092852900001395
https://doi.org/10.1017/s1092852900001395
Publikováno v:
The Journal of Neuroscience. 17:1710-1719
The norepinephrine transporter (NET) is a site of action for tricyclic antidepressant drugs and for drugs of abuse such as amphetamine and cocaine. In this study, the binding of [3H]nisoxetine to NETs in the noradrenergic cell group, the locus coerul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5839e9208e42a106b1de1699fe6f1209
https://doi.org/10.1523/jneurosci.17-05-01710.1997
https://doi.org/10.1523/jneurosci.17-05-01710.1997
Autor:
Gregory A. Ordway, Violetta Klimek
Publikováno v:
Brain Research. 741:263-274
Recent reports of specific topographic patterns of cell loss in the locus coeruleus (LC) in psychiatric and neurologic disorders underscores the need for detailed neurochemical analyses of this cell group. In this study, the anatomical distribution o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0a30fadee41afd2f1f94197d884c45
https://doi.org/10.1016/s0006-8993(96)00937-7
https://doi.org/10.1016/s0006-8993(96)00937-7
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 28(7)
Research evidence that corticotropin-releasing factor (CRF) plays a role in the pathophysiology of major depressive disorder (MDD) has accumulated over the past 20 years. The elevation of lumbar cerebrospinal fluid (CSF) concentrations of CRF decreas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7aab002600518a50bb861760256307
https://pubmed.ncbi.nlm.nih.gov/12784115
https://pubmed.ncbi.nlm.nih.gov/12784115