Výsledky vyhledávání - "Violeta, Morin"

Akademický článek

Biodegradation of Polystyrene by Galleria mellonella: Identification of Potential Enzymes Involved in the Degradative Pathway

Autor: Sebastián Venegas, Carolina Alarcón, Juan Araya, Marcell Gatica, Violeta Morin, Estefanía Tarifeño-Saldivia, Elena Uribe

Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 3, p 1576 (2024)

Galleria mellonella is a lepidopteran whose larval stage has shown the ability to degrade polystyrene (PS), one of the most recalcitrant plastics to biodegradation. In the present study, we fed G. mellonella larvae with PS for 54 days and determined

Externí odkaz: https://doaj.org/article/33cb7fecc76e4c269498c1c58ee3e96a

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Akademický článek

Hakai is required for stabilization of core components of the m6A mRNA methylation machinery

Autor: Praveen Bawankar, Tina Lence, Chiara Paolantoni, Irmgard U. Haussmann, Migle Kazlauskiene, Dominik Jacob, Jan B. Heidelberger, Florian M. Richter, Mohanakarthik P. Nallasivan, Violeta Morin, Nastasja Kreim, Petra Beli, Mark Helm, Martin Jinek, Matthias Soller, Jean-Yves Roignant

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

The E3 ligase Hakai can interact with the m6A methylation machinery but its function is still unclear. Here, the authors show that Hakai is a conserved component of the m6A methyltransferase complex and provide functional and molecular insights into

Externí odkaz: https://doaj.org/article/fecec708c84b4bd4904def2c94ce32a6

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Akademický článek

Blocking the Farnesyl Pocket of PDEδ Reduces Rheb-Dependent mTORC1 Activation and Survival of Tsc2-Null Cells

Autor: Marisol Estrella Armijo, Emilia Escalona, Daniela Peña, Alejandro Farias, Violeta Morin, Matthias Baumann, Bert Matthias Klebl, Roxana Pincheira, Ariel Fernando Castro

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Rheb is a small GTPase member of the Ras superfamily and an activator of mTORC1, a protein complex master regulator of cell metabolism, growth, and proliferation. Rheb/mTORC1 pathway is hyperactivated in proliferative diseases, such as Tuberous Scler

Externí odkaz: https://doaj.org/article/b836196e338f4d45b9d4ac930431cb8c

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Akademický článek

Comprehensive Characterization of the Complex lola Locus Reveals a Novel Role in the Octopaminergic Pathway via Tyramine Beta-Hydroxylase Regulation

Autor: Nadja Dinges, Violeta Morin, Nastasja Kreim, Tony D. Southall, Jean-Yves Roignant

Publikováno v: Cell Reports, Vol 21, Iss 10, Pp 2911-2925 (2017)

Summary: Longitudinals lacking (lola) is one of the most complex genes in Drosophila melanogaster, encoding up to 20 protein isoforms that include key transcription factors involved in axonal pathfinding and neural reprogramming. Most previous studie

Externí odkaz: https://doaj.org/article/ec501e09afa24712afb98fcaebfa1f62

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Effects of salinity changes on hatching, hatching-gene expression, and hatching-enzyme expression in anchoveta Engraulis ringens eggs

Autor: Violeta Morin, Samuel Soto, Matías Gonzalez, Andrea Miranda, Leonardo R. Castro, Oger Tiznado

Publikováno v: Marine Ecology Progress Series. 658:181-194

The Peruvian anchoveta Engraulis ringens is one of the most important commercial fishes along the Humboldt Current. Previous studies have shown that egg quality (volume, protein and lipid content) and hatching rates decrease during the spawning seaso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac9b43beadcca90e328f7aca94853900
https://doi.org/10.3354/meps13548

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Akademický článek

Transcriptional Auto-Regulation of RUNX1 P1 Promoter.

Autor: Milka Martinez, Marcela Hinojosa, Daniel Trombly, Violeta Morin, Janet Stein, Gary Stein, Amjad Javed, Soraya E Gutierrez

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0149119 (2016)

RUNX1 a member of the family of runt related transcription factors (RUNX), is essential for hematopoiesis. The expression of RUNX1 gene is controlled by two promoters; the distal P1 promoter and the proximal P2 promoter. Several isoforms of RUNX1 mRN

Externí odkaz: https://doaj.org/article/07c882e205444f1dbae6375f29ee6612

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Hakai is required for stabilization of core components of the m6A mRNA methylation machinery

Autor: Mohanakarthik Ponnadai Nallasivan, Irmgard U. Haussmann, Jan B. Heidelberger, Mark Helm, Violeta Morin, Tina Lence, Migle Kazlauskiene, Nastasja Kreim, Jean-Yves Roignant, Florian Richter, Chiara Paolantoni, Dominik Jacob, Martin Jinek, Matthias Soller, Petra Beli, Praveen Bawankar

Publikováno v: Nature communications, vol. 12, no. 1, pp. 3778
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

N6-methyladenosine (m6A) is the most abundant internal modification on mRNA which influences most steps of mRNA metabolism and is involved in several biological functions. The E3 ubiquitin ligase Hakai was previously found in complex with components

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9197b6a2a94e349753dc169b857c253
https://serval.unil.ch/notice/serval:BIB_C0C803938C71

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Variants in PUS7 Cause Intellectual Disability with Speech Delay, Microcephaly, Short Stature, and Aggressive Behavior

Publikováno v: The American Journal of Human Genetics
American Journal of Human Genetics, 103, 1045-1052
American Journal of Human Genetics, 103, 6, pp. 1045-1052

We describe six persons from three families with three homozygous protein truncating variants in PUS7: c.89_90del (p.Thr30Lysfs(∗)20), c.1348C>T (p.Arg450(∗)), and a deletion of the penultimate exon 15. All these individuals have intellectual dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffde4fc4129ca32880c4e40085b728c
https://doi.org/10.1016/j.ajhg.2018.10.026

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Hakai is required for stabilization of core components of the m

Autor: Praveen, Bawankar, Tina, Lence, Chiara, Paolantoni, Irmgard U, Haussmann, Migle, Kazlauskiene, Dominik, Jacob, Jan B, Heidelberger, Florian M, Richter, Mohanakarthik P, Nallasivan, Violeta, Morin, Nastasja, Kreim, Petra, Beli, Mark, Helm, Martin, Jinek, Matthias, Soller, Jean-Yves, Roignant

Publikováno v: Nature Communications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::304af2c7d8ba435c4b60ecd069cbd355
https://pubmed.ncbi.nlm.nih.gov/34145251

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