Výsledky vyhledávání - "Violaine Mottier-Pavie"

Modulation of the Hippo pathway and organ growth by RNA processing proteins

Autor: Leticia Sansores-Garcia, Kathleen M Gajewski, Robert Andrew Mills, Leen Van Huffel, Mardelle Atkins, Violaine Mottier-Pavie, Jana Mach, Weronika Kowalczyk, Jun Xie, Georg Halder, Gordon B. Mills

Publikováno v: Proceedings of the National Academy of Sciences. 115:10684-10689

The Hippo tumor-suppressor pathway regulates organ growth, cell proliferation, and stem cell biology. Defects in Hippo signaling and hyperactivation of its downstream effectors-Yorkie (Yki) in Drosophila and YAP/TAZ in mammals-result in progenitor ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0125ddc9200fb2ff0c5c5e17f388385d
https://doi.org/10.1073/pnas.1807325115

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Misato Controls Mitotic Microtubule Generation by Stabilizing the TCP-1 Tubulin Chaperone Complex

Autor: Kate J. Heesom, Valeria Palumbo, Silvia Bonaccorsi, Kacper B. Rogala, Claudia Pellacani, James G. Wakefield, Charlotte M. Deane, Violaine Mottier-Pavie, Maurizio Gatti

Publikováno v: Current Biology
Palumbo, LV, Pellacani, C, Heesom, K J, Rogala, K, Deane, C, Mottier-Pavie, V, Gatti, M, Bonaccorsi, S & Wakefield, J G 2015, ' Misato Controls Mitotic Microtubule Generation by Stabilizing the TCP-1 Tubulin Chaperone Complex ', Current Biology, pp. 1777-1783 . https://doi.org/10.1016/j.cub.2015.05.033

SummaryMitotic spindles are primarily composed of microtubules (MTs), generated by polymerization of α- and β-Tubulin hetero-dimers [1, 2]. Tubulins undergo a series of protein folding and post-translational modifications in order to fulfill their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a0a7f0d6bf396d937b1421669a4b5d
https://doi.org/10.1016/j.cub.2015.05.033

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The Wnt pathway limits BMP signaling outside of the germline stem cell niche in Drosophila ovaries

Autor: Victor Palacios, Michael Buszczak, Violaine Mottier-Pavie, Shane Scoggin, Susan Eliazer

The mechanisms that modulate and limit the signaling output of adult stem cell niches remain poorly understood. To gain further insights into how these microenvironments are regulated in vivo, we performed a candidate gene screen designed to identify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e57fa3bcd565da41105de0708d8789
https://europepmc.org/articles/PMC5001506/

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The relative roles of centrosomal and kinetochore-driven microtubules in Drosophila spindle formation

Autor: Silvia Bonaccorsi, Elisabetta Bucciarelli, Maria Patrizia Somma, Ramona Lattao, Claudia Pellacani, Maria Grazia Giansanti, Violaine Mottier-Pavie, Maurizio Gatti

Publikováno v: Experimental Cell Research
Experimental Cell Research, Elsevier, 2012, 318 (12), pp.1375-80. ⟨10.1016/j.yexcr.2012.05.001⟩
Experimental cell research 318 (2012): 1375–1380. doi:10.1016/j.yexcr.2012.05.001
info:cnr-pdr/source/autori:Gatti, Maurizio; Bucciarelli, Elisabetta; Lattao, Ramona; Pellacani, Claudia; Mottier-Pavie, Violaine; Giansanti, Maria Grazia; Somma, Maria Patrizia; Bonaccorsi, Silvia/titolo:The relative roles of centrosomal and kinetochore-driven microtubules in Drosophila spindle formation/doi:10.1016%2Fj.yexcr.2012.05.001/rivista:Experimental cell research/anno:2012/pagina_da:1375/pagina_a:1380/intervallo_pagine:1375–1380/volume:318

Mitotic spindle assembly in centrosome-containing cells relies on two main microtubule (MT) nucleation pathways, one based on centrosomes and the other on chromosomes. However, the relative role of these pathways is not well defined. Here we review t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4f3d6201522d475fd01ec80f7077b3
https://doi.org/10.1016/j.yexcr.2012.05.001

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MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

Autor: Kun-Liang Guan, Hyun Woo Park, Georg Halder, Audrey W. Hong, Wenqi Lu, Zhipeng Meng, Fabian Flores, Shicong Lu, Fa-Xing Yu, Violaine Mottier-Pavie, Carsten G. Hansen, Toshiro Moroishi, Steven W. Plouffe, Jung-Soon Mo

Publikováno v: Nature Communications
Nature communications, vol 6, iss 1

The Hippo pathway plays a central role in tissue homoeostasis, and its dysregulation contributes to tumorigenesis. Core components of the Hippo pathway include a kinase cascade of MST1/2 and LATS1/2 and the transcription co-activators YAP/TAZ. In res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f34159e7ebc0cb7aca66df65e44e620
http://europepmc.org/articles/PMC4600732

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Misato Controls Mitotic Microtubule Generation by Stabilizing the TCP-1 Tubulin Chaperone Complex (vol 25, pg 1777, 2015)

Autor: Valeria Palumbo 1, Claudia Pellacani 2, Kate J Heesom 3, Kacper B Rogala 4, Charlotte M Deane 4, Violaine Mottier-Pavie 2, Maurizio Gatti 5, Silvia Bonaccorsi 6, James G Wakefield 7

Publikováno v: Current biology 25 (2015): 2063–2063. doi:10.1016/j.cub.2015.07.035
info:cnr-pdr/source/autori:Valeria Palumbo 1, Claudia Pellacani 2, Kate J Heesom 3, Kacper B Rogala 4, Charlotte M Deane 4, Violaine Mottier-Pavie 2, Maurizio Gatti 5, Silvia Bonaccorsi 6, James G Wakefield 7/titolo:Misato Controls Mitotic Microtubule Generation by Stabilizing the TCP-1 Tubulin Chaperone Complex (vol 25, pg 1777, 2015)/doi:10.1016%2Fj.cub.2015.07.035/rivista:Current biology/anno:2015/pagina_da:2063/pagina_a:2063/intervallo_pagine:2063–2063/volume:25

Mitotic spindles are primarily composed of microtubules (MTs), generated by polymerization of ?- and ?-Tubulin hetero-dimers. Tubulins undergo a series of protein folding and post-translational modifications in order to fulfill their functions. Defec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::1716959a788bea46b021b3e84d38a7c8
https://publications.cnr.it/doc/446291

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Phenotypic analysis of misato function reveals roles of noncentrosomal microtubules in Drosophila spindle formation

Autor: Silvia Bonaccorsi, Violaine Mottier-Pavie, Giovanni Cenci, Fiammetta Vernì, Maurizio Gatti

Publikováno v: Scopus-Elsevier
Journal of cell science (2011).
info:cnr-pdr/source/autori:Mottier-Pavie V., Cenci G., Vernì F., Gatti M. and Bonaccorsi S./titolo:Phenotypic analysis of misato function reveals roles of noncentrosomal microtubules inDrosophila spindle formation/doi:/rivista:Journal of cell science/anno:2011/pagina_da:/pagina_a:/intervallo_pagine:/volume
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2011, 124 (Pt 5), pp.706-17. ⟨10.1242/jcs.072348⟩

International audience; Mitotic spindle assembly in centrosome-containing cells relies on two main microtubule (MT) nucleation pathways, one based on centrosomes and the other on chromosomes. However, the relative role of these pathways is not well d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bf98afd6824f45799a9967686eddd0
https://pubmed.ncbi.nlm.nih.gov/21285248

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Drosophila Bld10 Is a Centriolar Protein That Regulates Centriole, Basal Body, and Motile Cilium Assembly

Autor: Violaine Mottier-Pavie, Timothy L. Megraw

Cilia and flagella play multiple essential roles in animal development and cell physiology. Defective cilium assembly or motility represents the etiological basis for a growing number of human diseases. Therefore, how cilia and flagella assemble and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc1bcc71baf8640db2029f731e9a1b3
https://europepmc.org/articles/PMC2682601/

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