Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Violaine Moreau"'
Autor:
Camille Dantzer, Justine Vaché, Aude Brunel, Isabelle Mahouche, Anne-Aurélie Raymond, Jean-William Dupuy, Melina Petrel, Paulette Bioulac-Sage, David Perrais, Nathalie Dugot-Senant, Mireille Verdier, Barbara Bessette, Clotilde Billottet, Violaine Moreau
Publikováno v:
eLife, Vol 13 (2024)
Immune checkpoint inhibitors have produced encouraging results in cancer patients. However, the majority of ß-catenin-mutated tumors have been described as lacking immune infiltrates and resistant to immunotherapy. The mechanisms by which oncogenic
Externí odkaz:
https://doaj.org/article/342f26d4191d4cf39318d96525b6cc9f
Autor:
Sara Basbous, Lydia Dif, Camille Dantzer, Sylvaine Di-Tommaso, Jean-William Dupuy, Paulette Bioulac-Sage, Anne-Aurélie Raymond, Chantal Desdouets, Frédéric Saltel, Violaine Moreau
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Entosis is a process that leads to the formation of cell-in-cell structures commonly found in cancers. Here, we identified entosis in hepatocellular carcinoma and the loss of Rnd3 (also known as RhoE) as an efficient inducer of this mechanis
Externí odkaz:
https://doaj.org/article/00a999658bed44e197ffd3d054843606
Autor:
Caroline Gest, Sandra Sena, Lydia Dif, Véronique Neaud, Robin Loesch, Nathalie Dugot-Senant, Lisa Paysan, Léo Piquet, Terezinha Robbe, Nathalie Allain, Doulaye Dembele, Catherine Guettier, Paulette Bioulac-Sage, Anne Rullier, Brigitte Le Bail, Christophe F. Grosset, Frédéric Saltel, Valérie Lagrée, Sabine Colnot, Violaine Moreau
Publikováno v:
JHEP Reports, Vol 5, Iss 5, Pp 100691- (2023)
Background & Aims: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours. Those mutations are mostly hetero
Externí odkaz:
https://doaj.org/article/842490d9fd564a5d9087b3a228132176
Autor:
Ana Zúñiga, Sarah Guiziou, Pauline Mayonove, Zachary Ben Meriem, Miguel Camacho, Violaine Moreau, Luca Ciandrini, Pascal Hersen, Jerome Bonnet
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Automated frameworks to systematically implement robust history-dependent genetic programs in cellular populations.
Externí odkaz:
https://doaj.org/article/cb01020059414899ba529e5529a96b48
Autor:
Vincent Demolombe, Alexandre G. de Brevern, Franck Molina, Géraldine Lavigne, Claude Granier, Violaine Moreau
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-17 (2019)
Abstract Background Computational methods provide approaches to identify epitopes in protein Ags to help characterizing potential biomarkers identified by high-throughput genomic or proteomic experiments. PEPOP version 1.0 was developed as an antigen
Externí odkaz:
https://doaj.org/article/d122ef562cb14147a2cda04b140f19e0
Autor:
Vincent Demolombe, Alexandre G. de Brevern, Liza Felicori, Christophe NGuyen, Ricardo Andrez Machado de Avila, Lionel Valera, Bénédicte Jardin-Watelet, Géraldine Lavigne, Aurélien Lebreton, Franck Molina, Violaine Moreau
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background Bioinformatics methods are helpful to identify new molecules for diagnostic or therapeutic applications. For example, the use of peptides capable of mimicking binding sites has several benefits in replacing a protein which is diff
Externí odkaz:
https://doaj.org/article/ff515995205d4f2abb939e660c9c70f5
Autor:
Zakaria Ezzoukhry, Elodie Henriet, Fabrice P. Cordelières, Jean-William Dupuy, Marlène Maître, Nathan Gay, Sylvaine Di-Tommaso, Luc Mercier, Jacky G. Goetz, Marion Peter, Frédéric Bard, Violaine Moreau, Anne-Aurélie Raymond, Frédéric Saltel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Invadosomes degrade extracellular matrix and facilitate cell invasion but their molecular composition is not fully understood. Here, the authors combine laser capture and mass spectrometry to map the proteome of invadosomes, showing that they rely on
Externí odkaz:
https://doaj.org/article/2c995818d6d044ceb85f3e411b0ea6e8
Autor:
Claude Bobo, Claire Céré, Mélody Dufossée, Alain Dautant, Violaine Moreau, Stéphen Manon, Florian Beaumatin, Muriel Priault
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5571 (2019)
Bcl-xL is an oncogene of which the survival functions are finely tuned by post-translational modifications (PTM). Within the Bcl-2 family of proteins, Bcl-xL shows unique eligibility to deamidation, a time-related spontaneous reaction. Deamidation is
Externí odkaz:
https://doaj.org/article/2084921ce6fe4ee68c07ffdbb5b7636a
Publikováno v:
Cells, Vol 8, Iss 4, p 351 (2019)
Small guanosine triphosphatases (GTPases) gathered in the Rat sarcoma (Ras) superfamily represent a large family of proteins involved in several key cellular mechanisms. Within the Ras superfamily, the Ras homolog (Rho) family is specialized in the r
Externí odkaz:
https://doaj.org/article/77201b8ab6344ed2b06d0b4b9e4c3fbb
Autor:
Thomas Pradeu, Bertrand Daignan‐Fornier, Andrew Ewald, Pierre‐Luc Germain, Samir Okasha, Anya Plutynski, Sébastien Benzekry, Marta Bertolaso, Mina Bissell, Joel S. Brown, Benjamin Chin‐Yee, Ian Chin‐Yee, Hans Clevers, Laurent Cognet, Marie Darrason, Emmanuel Farge, Jean Feunteun, Jérôme Galon, Elodie Giroux, Sara Green, Fridolin Gross, Fanny Jaulin, Rob Knight, Ezio Laconi, Nicolas Larmonier, Carlo Maley, Alberto Mantovani, Violaine Moreau, Pierre Nassoy, Elena Rondeau, David Santamaria, Catherine M. Sawai, Andrei Seluanov, Gregory D. Sepich‐Poore, Vanja Sisirak, Eric Solary, Sarah Yvonnet, Lucie Laplane
Publikováno v:
Biological Reviews.