Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Violaine Goidts"'
Autor:
Emma Phillips, Jörg Balss, Frederic Bethke, Stefan Pusch, Stefan Christen, Thomas Hielscher, Martina Schnölzer, Michael N. C. Fletcher, Antje Habel, Claudia Tessmer, Lisa-Marie Brenner, Mona Göttmann, David Capper, Christel Herold-Mende, Andreas von Deimling, Sarah-Maria Fendt, Violaine Goidts
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract Glioblastoma is a highly aggressive brain tumor for which there is no cure. The metabolic enzyme 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4 (PFKFB4) is essential for glioblastoma stem-like cell (GSC) survival but its mode of actio
Externí odkaz:
https://doaj.org/article/a08fd162f6184b9cb768a5cefba94123
Autor:
Peng Cheng, Emma Phillips, Sung-Hak Kim, David Taylor, Thomas Hielscher, Laura Puccio, Anita B. Hjelmeland, Peter Lichter, Ichiro Nakano, Violaine Goidts
Publikováno v:
Stem Cell Reports, Vol 4, Iss 5, Pp 899-913 (2015)
Glioblastoma is a highly lethal cancer for which novel therapeutics are urgently needed. Two distinct subtypes of glioblastoma stem-like cells (GSCs) were recently identified: mesenchymal (MES) and proneural (PN). To identify mechanisms to target the
Externí odkaz:
https://doaj.org/article/049ca687476b4b6099305c151ca87f59
Autor:
Sara Kildgaard, Karolina Subko, Emma Phillips, Violaine Goidts, Mercedes de la Cruz, Caridad Díaz, Charlotte H. Gotfredsen, Birgitte Andersen, Jens C. Frisvad, Kristian F. Nielsen, Thomas O. Larsen
Publikováno v:
Marine Drugs, Vol 15, Iss 8, p 253 (2017)
A marine-derived Stilbella fimetaria fungal strain was screened for new bioactive compounds based on two different approaches: (i) bio-guided approach using cytotoxicity and antimicrobial bioassays; and (ii) dereplication based approach using liquid
Externí odkaz:
https://doaj.org/article/2ee213ebeff34a5895b82272553daf26
Autor:
Christel Herold-Mende, Bernhard Radlwimmer, Andreas Unterberg, Peter Lichter, Philipp Beckhove, Wilfried Roth, Volker Eckstein, Burkhard M. Helmke, Violaine Goidts, Stephanie E. Combs, Georg Gdynia, Christine Dictus, Jennifer Lohr, Rezvan Ahmadi, Katrin E. Tagscherer, Felix Zeppernick, Aurélie Ernst, Mohammad Farhadi, Feng Wan, Benito Campos
Supplementary Data from Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba0cb8ff78da76fdfe5ff9ef47e2e17
https://doi.org/10.1158/1078-0432.22440015.v1
https://doi.org/10.1158/1078-0432.22440015.v1
Autor:
Christel Herold-Mende, Bernhard Radlwimmer, Andreas Unterberg, Peter Lichter, Philipp Beckhove, Wilfried Roth, Volker Eckstein, Burkhard M. Helmke, Violaine Goidts, Stephanie E. Combs, Georg Gdynia, Christine Dictus, Jennifer Lohr, Rezvan Ahmadi, Katrin E. Tagscherer, Felix Zeppernick, Aurélie Ernst, Mohammad Farhadi, Feng Wan, Benito Campos
Purpose: Stem-like tumor cells comprise a highly tumorigenic and therapy-resistant tumor subpopulation, which is believed to substantially influence tumor initiation and therapy resistance in glioma. Currently, therapeutic, drug-induced differentiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b8a2aa679cba715854cf259aa3cdf5
https://doi.org/10.1158/1078-0432.c.6517395
https://doi.org/10.1158/1078-0432.c.6517395
Autor:
Emma Phillips, Jörg Balss, Frederic Bethke, Stefan Pusch, Stefan Christen, Thomas Hielscher, Martina Schnölzer, Michael N. C. Fletcher, Antje Habel, Claudia Tessmer, Lisa-Marie Brenner, Mona Göttmann, David Capper, Christel Herold-Mende, Andreas von Deimling, Sarah-Maria Fendt, Violaine Goidts
Glioblastoma is a highly aggressive brain tumor for which there is no cure. The metabolic enzyme 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4 (PFKFB4) is essential for glioblastoma stem-like cell (GSC) survival but its mode of action is uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7754ce7b3ff05040653481e4ebc00749
https://lirias.kuleuven.be/handle/20.500.12942/706899
https://lirias.kuleuven.be/handle/20.500.12942/706899
Autor:
Joshua C. Anderson, Svetlana Komarova, Ahmed Ibrahim, Dagoberto Estevez-Ordonez, Amr Alwakeal, Violaine Goidts, Moaaz Abdelrashid, Christopher D. Willey, Daisuke Yamashita, Ichiro Nakano, James M. Markert
Publikováno v:
J Neurosurg
OBJECTIVEDespite significant recent efforts applied toward the development of efficacious therapies for glioblastoma (GBM) through exploration of GBM’s genome and transcriptome, curative therapeutic strategies remain highly elusive. As such, novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5725b5ec854937c94534000f3c8a79
https://doi.org/10.3171/2019.7.jns191376
https://doi.org/10.3171/2019.7.jns191376
Autor:
Areeba Patel, Helin Dogan, Alexander Jung, Zaira Seferbekova, Alexander Payne, Michael Ritter, Daniel Schrimpf, Damian Stichel, Stefan Hamelmann, Christina Blume, Philipp Euskirchen, Violaine Goidts, Martin Sill, Stefan Pfister, Matthew Loose, Wolfgang Wick, Andreas von Deimling, David T Jones, Matthias Schlesner, Moritz Gerstung, Felix Sahm
Publikováno v:
Neuro-Oncology. 24:vii161-vii161
BACKGROUND Integrative brain tumour diagnostics indisputably requires comprehensive reporting of molecular markers. The 2021 WHO classification of central nervous system (CNS) tumours substantially increased the set of markers for routine evaluation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f52c486fcd3d7faf845c20ed0362f928
https://doi.org/10.1093/neuonc/noac209.619
https://doi.org/10.1093/neuonc/noac209.619
Autor:
Michael N. C. Fletcher, Shaman Rahman, Tolga Lokumcu, Bryan W. Day, Laura Puccio, Tobias Kessler, Ulrich Baumgartner, Felix Sahm, Wolfgang Wick, Thomas Hielscher, Silja Schlue, Obada T Alhalabi, Ling Hai, Lea Hansen-Palmus, Elena Wittmann, Emma Phillips, Mona Göttmann, Christel Herold-Mende, Ichiro Nakano, Violaine Goidts
Publikováno v:
Neuro Oncol
Background Glioblastoma is the most common primary malignancy of the central nervous system with a dismal prognosis. Genomic signatures classify isocitrate dehydrogenase 1 (IDH)-wildtype glioblastoma into three subtypes: proneural, mesenchymal, and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e81b56ecce2a59d2254392ed6da7ae9
https://europepmc.org/articles/PMC8730774/
https://europepmc.org/articles/PMC8730774/
Autor:
Dongquan Chen, Ichiro Nakano, Peng Cheng, Hong-yu Li, Do-Hyun Nam, Yong Jae Shin, Marat Pavliukov, Yeri Lee, Jia Wang, Brendan Frett, Wanfu Xie, Violaine Goidts, Sung Hak Kim, Wenhao Hu, Daisuke Yamashita, Zhuo Zhang, Mayu A Nakano
The highly lethal brain cancer glioblastoma undergoes dynamic changes in molecular profile and cellular phenotype throughout tumor core establishment and in primary-to-recurrent tumor progression. These dynamic changes allow glioblastoma tumors to es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7f3325d121978525a5a24003a95476
https://doi.org/10.1101/2020.12.01.405696
https://doi.org/10.1101/2020.12.01.405696