Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Viola Nähse"'
Autor:
Viola Nähse, Camilla Raiborg, Kia Wee Tan, Sissel Mørk, Maria Lyngaas Torgersen, Eva Maria Wenzel, Mireia Nager, Veijo T. Salo, Terje Johansen, Elina Ikonen, Kay Oliver Schink, Harald Stenmark
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cellular homeostasis is governed by removal of damaged organelles and protein aggregates by selective autophagy mediated by cargo adaptors such as p62/SQSTM1. Autophagosomes can assemble in specialized cup-shaped regions of the endoplasmic r
Externí odkaz:
https://doaj.org/article/4b4cc69eb99844d38600776ee09b1dd5
Autor:
Philippe Fernandes, Benoit Miotto, Claude Saint-Ruf, Maha Said, Viviana Barra, Viola Nähse, Silvia Ravera, Enrico Cappelli, Valeria Naim
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Fernandes et al. discover a connection between the mitochondrial stress response and genomic stability. They find that transcription of common fragile site (CFS) genes is induced by mitochondrial stress, whereas a regulator of CFS stability, FANCD2,
Externí odkaz:
https://doaj.org/article/e0f19b4840814983bdab55f7127e98cd
Autor:
Olivier Brison, Sami El-Hilali, Dana Azar, Stéphane Koundrioukoff, Mélanie Schmidt, Viola Nähse, Yan Jaszczyszyn, Anne-Marie Lachages, Bernard Dutrillaux, Claude Thermes, Michelle Debatisse, Chun-Long Chen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Common Fragile Sites (CFSs) are chromosome regions prone to breakage upon replication stress known to drive chromosome rearrangements during oncogenesis. Here the authors use genome-wide and single cell techniques to assess how replication timing and
Externí odkaz:
https://doaj.org/article/faa892657e9143c2a1486f882b9f0db1
Autor:
Eva Maria Wenzel, Sebastian Wolfgang Schultz, Kay Oliver Schink, Nina Marie Pedersen, Viola Nähse, Andreas Carlson, Andreas Brech, Harald Stenmark, Camilla Raiborg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Intraluminal vesicles are formed by the endosomal sorting complex required for transport (ESCRT) machinery. Here, the authors unravel the timing of vesicle budding, and that endosomal clathrin regulates concerted recruitment of ESCRT subcomplexes, re
Externí odkaz:
https://doaj.org/article/3a4d89a071f847dfb021b798caff85ef
Autor:
Piotr Grabarczyk, Viola Nähse, Martin Delin, Grzegorz Przybylski, Maren Depke, Petra Hildebrandt, Uwe Völker, Christian A Schmidt
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12532 (2010)
The expression of BCL11B was reported in T-cells, neurons and keratinocytes. Aberrations of BCL11B locus leading to abnormal gene transcription were identified in human hematological disorders and corresponding animal models. Recently, the elevated l
Externí odkaz:
https://doaj.org/article/c6bb91389b5b48bb9dad57bdc45f23a9
Autor:
Randi G. Syljuåsen, Einar K. Rofstad, Kinga Tkacz-Stachowska, Viola Nähse-Kumpf, Grete Hasvold
PDF - 491K, Supplementary Figure S1: Cell cycle progression following hypoxia treatment. Supplementary Figure S2: Clonogenic survival following depletion of CHK1 by siRNA transfection. Supplementary Figure S3: S phase damage in HCT116p53-/- and HT29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851723fd69fb19c9d51f32e5da1f3f39
https://doi.org/10.1158/1535-7163.22497537.v1
https://doi.org/10.1158/1535-7163.22497537.v1
Autor:
Randi G. Syljuåsen, Einar K. Rofstad, Kinga Tkacz-Stachowska, Viola Nähse-Kumpf, Grete Hasvold
Inhibitors of CHK1 are in clinical trials for cancer treatment in combination with DNA-damaging agents. Importantly, it was previously suggested that hypoxic cancer cells may be particularly sensitive to CHK1 inhibition. However, this suggestion was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5853574abc1174612c31dc42c0345299
https://doi.org/10.1158/1535-7163.c.6535647.v1
https://doi.org/10.1158/1535-7163.c.6535647.v1
Autor:
Viola Nähse, Camilla Raiborg, Kia Wee Tan, Sissel Mørk, Maria Lyngaas Torgersen, Eva Maria Wenzel, Mireia Nager, Veijo T. Salo, Terje Johansen, Elina Ikonen, Kay Oliver Schink, Harald Stenmark
Cellular homeostasis is governed by removal of damaged organelles and protein aggregates by selective autophagy mediated by cargo adaptors such as p62/SQSTM1. Autophagosomes can assemble in specialized cup-shaped regions of the endoplasmic reticulum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac318edd18eab870be7b3abf1cc4456
https://doi.org/10.21203/rs.3.rs-1322004/v1
https://doi.org/10.21203/rs.3.rs-1322004/v1
Autor:
Claude Saint-Ruf, Viviana Barra, Silvia Ravera, Philippe Fernandes, Viola Nähse, Enrico Cappelli, Valeria Naim, Benoit Miotto, Maha Said
Publikováno v:
Communications Biology
Communications Biology, Nature Publishing Group, 2021, 4 (1), pp.127. ⟨10.1038/s42003-021-01647-8⟩
Communications Biology, 2021, 4 (1), pp.127. ⟨10.1038/s42003-021-01647-8⟩
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Communications Biology, Nature Publishing Group, 2021, 4 (1), pp.127. ⟨10.1038/s42003-021-01647-8⟩
Communications Biology, 2021, 4 (1), pp.127. ⟨10.1038/s42003-021-01647-8⟩
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Common fragile sites (CFSs) are genomic regions frequently involved in cancer-associated rearrangements. Most CFSs lie within large genes, and their instability involves transcription- and replication-dependent mechanisms. Here, we uncover a role for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312fa6c078e83715a37fdd25a2eed7f3
https://www.hal.inserm.fr/inserm-03357197
https://www.hal.inserm.fr/inserm-03357197