Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Viola Lanier"'
Autor:
Kaamilah Wilson, Corey Gillespie, Monica Battle, Alexander Quarshie, Viola Lanier, Marta Torroella-Kouri, Ruben R. Gonzalez-Perez, Tia L. Harmon
Publikováno v:
International Journal of Cancer. 134:1605-1616
To investigate whether obesity induces a leptin-Notch signaling axis in breast cancer (BC), leptin-induced Notch was determined in human MCF-7 and MDA-MB231 and mouse E0771 cells and in E0771-BC hosted by syngeneic lean and diet-induced obesity (DIO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffe3ac186a04986b3e9aa9080916c662
https://doi.org/10.1002/ijc.28496
https://doi.org/10.1002/ijc.28496
Publikováno v:
Cancers
Cancers, Vol 5, Iss 3, Pp 1140-1162 (2013)
Cancers, Vol 5, Iss 3, Pp 1140-1162 (2013)
Obesity is linked to increased incidence of breast cancer. The precise causes and mechanisms of these morbid relationships are unknown. Contradictory data on leptin angiogenic actions have been published. However, accumulating evidence would suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f723adea1e570a81e46499befd2dcba2
http://europepmc.org/articles/PMC3795383
http://europepmc.org/articles/PMC3795383
Autor:
Lily Yang, Adriana Harbuzariu, Ruben R. Gonzalez-Perez, Ward Kirlin, Viola Lanier, Tia L. Harmon, Crystal C. Lipsey
Publikováno v:
World Journal of Clinical Oncology
Aim To develop a leptin peptide receptor antagonist linked to nanoparticles and determine its effect on viability of breast cancer cells. Methods The leptin antagonist, LPrA2, was coupled via EDAC [1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide] to ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710a76f3995f32dc6c30b1fa14324a73
https://pubmed.ncbi.nlm.nih.gov/28246585
https://pubmed.ncbi.nlm.nih.gov/28246585
Autor:
Gale W. Newman, Crystal C. Lipsey, Joy Milner, Johannes Waltenberger, Danielle Daley-Brown, Ruben R. Gonzalez-Perez, Viola Lanier, Leonard M. Anderson, Merle Leffers, Corey Gillespie, Nia Webb
Publikováno v:
The international journal of biochemistrycell biology. 79
Leptin increases vascular endothelial growth factor (VEGF), VEGF receptor-2 (VEGFR-2), and Notch expression in cancer cells, and transphosphorylates VEGFR-2 in endothelial cells. However, the mechanisms involved in leptin's actions in endothelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc469ca9db6847339995d106a7f9dc37
https://pubmed.ncbi.nlm.nih.gov/27590851
https://pubmed.ncbi.nlm.nih.gov/27590851
Autor:
Sha'Kayla Nunez, Viola Lanier, Ann Anu Kurian, Danielle Daley-Brown, Adriana Harbuzariu, Ruben R. Gonzalez, Tia L. Harmon, Crystal C. Lipsey
Publikováno v:
Molecular Cancer Therapeutics. 17:B046-B046
Obesity is pandemic and linked to higher incidence and poorer prognosis of several cancers, including pancreatic cancer (PC), triple-negative breast cancer (TNBC), and endometrial cancer type II (EmCa), which do not have targeted therapy. Commonly, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27c5a46fd3cfeede6be15da241360303
https://doi.org/10.1158/1535-7163.targ-17-b046
https://doi.org/10.1158/1535-7163.targ-17-b046
Autor:
Shakeyla Nunez, Viola Lanier, Pierre V. Candelaria, Cynthia Tchio, Adriana Harbuzariu, Ruben R. Gonzalez-Perez, Antonio Rampoldi, Danielle Daley-Brown, McKay Mullen, Tia L. Harmon, Courtney D. Dill, Crystal C. Lipsey, Ann Anu Kurian
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 26:B66-B66
Obesity incidence has reached alarming levels, particularly in minority populations: African American (AA) and Latinos. The risk of develop several cancers (i.e., breast, pancreatic and endometrial cancers) is strongly correlated to obesity. One of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99ac4b7b53fa3bfc28b6aa7bb1d46c84
https://doi.org/10.1158/1538-7755.disp16-b66
https://doi.org/10.1158/1538-7755.disp16-b66
Autor:
Monica, Battle, Corey, Gillespie, Alexander, Quarshie, Viola, Lanier, Tia, Harmon, Kaamilah, Wilson, Marta, Torroella-Kouri, Ruben R, Gonzalez-Perez
Publikováno v:
International journal of cancer. 134(7)
To investigate whether obesity induces a leptin–Notch signaling axis in breast cancer (BC), leptin-induced Notch was determined in human MCF-7 and MDA-MB231 and mouse E0771 cells and, in E0771-BC hosted by syngeneic lean and diet-induced-obesity (D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31493478972ecc67105f1b1d0d1195f4
https://pubmed.ncbi.nlm.nih.gov/24114531
https://pubmed.ncbi.nlm.nih.gov/24114531
Autor:
Pierre V. Candelaria, Antonio Rampoldi, Cynthia Tchio, Ruben R. Gonzalez-Perez, Tia L. Harmon, Adriana Harbuzariu, Courtney D. Dill, Danielle Daley-Brown, Crystal C. Lipsey, Viola Lanier
Publikováno v:
Cancer Research. 76:1026-1026
Background: Triple Negative Breast Cancer (TNBC) is an aggressive cancer with poor prognosis and is difficult to treat. Current standard therapy for the disease includes a combination of chemotherapeutic drugs: doxorubicin (DOX), paclitaxel (TAX), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7a531613db6a8bed6e360f2b434ecc7
https://doi.org/10.1158/1538-7445.am2016-1026
https://doi.org/10.1158/1538-7445.am2016-1026
Autor:
Tia L. Harmon, Courtney D. Dill, Lily Yang, Crystal C. Lipsey, Adriana Harbuzariu, Danielle Daley-Brown, Antonio Rampoldi, Ruben R. Gonzalez-Perez, Viola Lanier, Cynthia Tchio
Publikováno v:
Cancer Research. 76:2079-2079
Background: Breast cancer (BC) is an epidemic in the US. It is estimated that there will be over 230,000 new BC diagnoses in 2016. Triple Negative Breast Cancer (TNBC) comprises ∼15% of BC cases and lacks targeted therapeutic options. Obesity and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd3530c355717b92a232ef48ee8d879e
https://doi.org/10.1158/1538-7445.am2016-2079
https://doi.org/10.1158/1538-7445.am2016-2079
Autor:
Viola Lanier
Publikováno v:
Cancer Research. 76:227-227
Background: The tissue microenvironment plays a major role in tumor development and recurrence. It is known that leptin secreted by cancer and adipose cells can modify the tumor stroma, which is composed of immune, fibroblast, and endothelial cells (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e118cd257f9dab1da4870f617a1c1fb1
https://doi.org/10.1158/1538-7445.am2016-227
https://doi.org/10.1158/1538-7445.am2016-227