Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Viola, Tamási"'
Autor:
Kinga Tibori, Veronika Zámbó, Gabriella Orosz, Péter Szelényi, Farkas Sarnyai, Viola Tamási, Zsolt Rónai, Miklós Csala, Éva Kereszturi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Overnutrition and genetic predisposition are major risk factors for various metabolic disorders. Stearoyl-CoA desaturase-1 (SCD1) plays a key role in these conditions by synthesizing unsaturated fatty acids (FAs), thereby promoting fat stora
Externí odkaz:
https://doaj.org/article/bb61b555f5774ce8bfeae869108cc4f9
Autor:
Krisztina Németh, Blanka Tóth, Farkas Sarnyai, Anna Koncz, Dorina Lenzinger, Éva Kereszturi, Tamás Visnovitz, Brachyahu Meir Kestecher, Xabier Osteikoetxea, Miklós Csala, Edit I. Buzás, Viola Tamási
Publikováno v:
Nutrition & Metabolism, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background High fat diet (HFD) increases the likelihood of dyslipidemia, which can be a serious risk factor for atherosclerosis, diabetes or hepatosteatosis. Although changes in different blood lipid levels were broadly investigated, such al
Externí odkaz:
https://doaj.org/article/cd9628bf4f91440a9d9efeb8808eccbb
Autor:
Krisztina Németh, Peter Petschner, Krisztina Pálóczi, Nóra Fekete, Éva Pállinger, Edit I. Buzás, Viola Tamási
Publikováno v:
Life, Vol 12, Iss 5, p 642 (2022)
Background. tert-butylhydroquinone (tBHQ) is an antioxidant commonly used as a food additive. Studies suggest that tBHQ could modulate immune responses to influenza and SARS-CoV-2 infection. In our transcriptomic analysis we explored the molecular me
Externí odkaz:
https://doaj.org/article/bb8cbc201c014734a11553f77ce9f685
Autor:
András, Hrabák, Gábor, Bögel, József, Murányi, Viola, Tamási, Krisztina, Németh, Bálint, Szokol, Zoltán, Kukor, Tamás, Kardon, László, Őrfi
Publikováno v:
Molecular Immunology. 153:10-24
The JAK/STAT (Janus Kinase/Signal Transducer and Activator of Transcription) pathway plays a pivotal role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to reveal the relationship of activation
Autor:
Kinga Tibori, Gabriella Orosz, Veronika Zámbó, Péter Szelényi, Farkas Sarnyai, Viola Tamási, Zsolt Rónai, Judit Mátyási, Blanka Tóth, Miklós Csala, Éva Kereszturi
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6221
Disturbances in lipid metabolism related to excessive food intake and sedentary lifestyle are among major risk of various metabolic disorders. Stearoyl-CoA desaturase-1 (SCD1) has an essential role in these diseases, as it catalyzes the synthesis of
Autor:
Farkas Sarnyai, Éva Kereszturi, Kitti Szirmai, Judit Mátyási, Johanna Iman Al-Hag, Tamás Csizmadia, Péter Lőw, Péter Szelényi, Viola Tamási, Kinga Tibori, Veronika Zámbó, Blanka Tóth, Miklós Csala
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7298
Trans fatty acids (TFAs) are not synthesized in the human body but are generally ingested in substantial amounts. The widespread view that TFAs, particularly those of industrial origin, are unhealthy and contribute to obesity, cardiovascular diseases
Autor:
Viola Tamási, Peter Petschner, Csaba Adori, Eszter Kirilly, Romeo D Ando, Laszlo Tothfalusi, Gabriella Juhasz, Gyorgy Bagdy
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113662 (2014)
Venlafaxine (VLX), a serotonine-noradrenaline reuptake inhibitor, is one of the most commonly used antidepressant drugs in clinical practice for the treatment of major depressive disorder (MDD). Despite being more potent than its predecessors, simila
Externí odkaz:
https://doaj.org/article/5b79e46adffc4898bb059aa151b1e61c
Autor:
Margareta Porsmyr-Palmertz, Katalin Monostory, Viola Tamási, Eszter Hazai, Magnus Ingelman-Sundberg, László Vereczkey
Publikováno v:
Drug Metabolism and Disposition. 31:1310-1314
CYP2E1-inducing capacity of xenobiotics was determined in cultured hepatocytes on the basis of enzyme activities (chlorzoxazone 6-hydroxylation and 7-ethoxycoumarin O-dealkylation) and protein levels. Hepatocytes in culture showed rapid loss of CYP2E
Publikováno v:
Inflammation Research. 52:322-333
Differences in drug metabolism among individu- als are caused by numerous factors: differences in production and stability of mRNA of xenobiotic metabolizing enzymes, differences in the rate of enzyme synthesis and degradation, or enzyme inhibition.
Autor:
Viola Tamási, A. Falus
Publikováno v:
Topics on Drug Metabolism
Pharmacogenetics (or pharmacogenomics) studies the role of inherited and acquired genetic variation in drug response. Clinically relevant pharmacogenetic examples, mainly involving drug metabolism are known for decades, but the field was not evolved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1079193847769a664d35769bd04e33c9
https://doi.org/10.5772/36451
https://doi.org/10.5772/36451