Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Viola, Groehn"'
Autor:
Lisa Obermaier, Barbara Paes Miglioli da Mata, Caio Humberto Perego, Kátia Sivieri, Mateus Kawata Salgaço, André Gonzaga dos Santos, Ruth Boehni, Viola Groehn, Jean-Pierre Knapp, Michael Rychlik
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
Brazil has a diverse plant community, including underutilized non-conventional food crops (PANCs), which have the potential to be a rich source of food and contribute to food security. For assessing the folate content in a range of Brazilian PANCs, w
Externí odkaz:
https://doaj.org/article/fdc348e6d0e24bf18a70092ce9670afc
Autor:
Klaudia Siwowska, Roger Schibli, Cristina Müller, Simon M. Ametamey, Viola Groehn, Raffaella M. Schmid, Silvan D. Boss
Publikováno v:
The Journal of Nuclear Medicine, 60 (1)
The aim of this study was to develop the radiosyntheses of diastereomerically pure 6R- and 6S-3'-aza-2'-18F-fluoro-5-methyltetrahydrofolate (MTHF) (6R-18F-1 and 6S-18F-1) using the integrated approach and to compare the in vitro and in vivo performan
Autor:
Roger Schibli, Silvan D. Boss, Raffaella M. Schmid, Cristina Müller, Josephine I. Büchel, Klaudia Siwowska, Viola Groehn, Simon M. Ametamey
Publikováno v:
Bioconjugate Chemistry. 29:1119-1130
5-Methyltetrahydrofolate (5-MTHF), a reduced folate form, is the biologically active folate involved in many different metabolic processes. To date, there are no studies available in the literature on 18F-labeled 6S- and 6R-5-MTHF radiotracers for im
Autor:
Christina Müller, Stephanie Haller, Martina Benešová, Klaudia Siwowska, Viola Groehn, Roger Schibli, Peter Bernhardt, Francesca Bortoli
Publikováno v:
Molecular Pharmaceutics
Tumor targeting with folic acid radioconjugates has been proposed as a promising strategy for radionuclide therapy of folate receptor α (FR)-positive cancer. Recently, it was shown that modification of radiofolates with an albumin-binding entity inc
Autor:
Silvan D, Boss, Cristina, Müller, Klaudia, Siwowska, Raffaella M, Schmid, Viola, Groehn, Roger, Schibli, Simon M, Ametamey
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 60(1)
The aim of this study was to develop the radiosyntheses of diastereomerically pure 6
Autor:
Silvan D, Boss, Cristina, Müller, Klaudia, Siwowska, Josephine I, Büchel, Raffaella M, Schmid, Viola, Groehn, Roger, Schibli, Simon M, Ametamey
Publikováno v:
Bioconjugate chemistry. 29(4)
5-Methyltetrahydrofolate (5-MTHF), a reduced folate form, is the biologically active folate involved in many different metabolic processes. To date, there are no studies available in the literature on
Autor:
Stephanie Haller, Cristina Müller, Viola Groehn, Josefine Reber, Peter Bernhardt, Roger Schibli, Simone Brandt
Publikováno v:
Nuclear Medicine and Biology. 42:770-779
Introduction Application of therapeutic folate radioconjugates is a promising option for the treatment of folate receptor (FR)-positive tumors, although high uptake of radiofolates in the kidneys remains a critical issue. Recently, it was shown that
Publikováno v:
Pteridines, Vol 29, Iss 1, Pp 13-14 (2018)
Autor:
Josefine Reber, Stephanie Haller, Viola Groehn, Thomas Betzel, Cindy R. Fischer, Silvan D. Boss, Roger Schibli, Cristina Müller, Simon M. Ametamey
Publikováno v:
Bioconjugate chemistry. 27(1)
The folate receptor (FR) is upregulated in various epithelial cancer types (FR α-isoform), while healthy tissues show only restricted expression. FR-targeted imaging using folate radiopharmaceuticals is therefore a promising approach for the detecti
Autor:
Simon M. Ametamey, Roger Schibli, Thomas Betzel, Cristina Müller, Viola Groehn, Rudolf Moser, Tobias L. Ross
Publikováno v:
Synthesis. 2011:3639-3648