Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Vinzeigh N. Leukes"'
Autor:
Vinzeigh N. Leukes, Stephanus T. Malherbe, Andriette Hiemstra, Leigh A. Kotze, Kelly Roos, Alana Keyser, Dalene De Swardt, Andrea Gutschmidt, Gerhard Walzl, Nelita du Plessis
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Successful TB treatment is hampered by increasing resistance to the two most effective first-line anti-TB drugs, namely isoniazid and rifampicin, thus innovative therapies focused on host processes, termed host-directed therapies (HDTs), are promisin
Externí odkaz:
https://doaj.org/article/c412de5fcccf443887d1b48438fa8307
Autor:
Leigh A. Kotzé, Carly Young, Vinzeigh N. Leukes, Vini John, Zhuo Fang, Gerhard Walzl, Manfred B. Lutz, Nelita du Plessis
Publikováno v:
EBioMedicine, Vol 53, Iss , Pp - (2020)
Mycobacterium tuberculosis (M.tb) is likely the most successful human pathogen, capable of evading protective host immune responses and driving metabolic changes to support its own survival and growth. Ineffective innate and adaptive immune responses
Externí odkaz:
https://doaj.org/article/1a0e3d9e8311438990e96e6f9a8af54f
Autor:
Charles M, Manyelo, Regan S, Solomons, Candice I, Snyders, Martin, Kidd, Yajna, Kooblal, Vinzeigh N, Leukes, Conita, Claassen, Kelly, Roos, Kim, Stanley, Gerhard, Walzl, Novel N, Chegou
Publikováno v:
Biomarkers. 27:549-561
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d074750bc37a246e6fb31f42f6c0e69d
https://doi.org/10.1080/1354750x.2022.2071991
https://doi.org/10.1080/1354750x.2022.2071991
Autor:
Vinzeigh N. Leukes, Novel N. Chegou, Nosipho Mtala, Wolfgang Preiser, Stephanus T. Malherbe, Marika Flinn, Conita Claassen, Donald Simon, Gerhard Walzl, Candice E. MacDonald, Tracy Cummins, Jane A. Shaw, Gerard Tromp, Andre G. Loxton, Kim Stanley, Andriëtte Hiemstra, Léanie Kleynhans, Helmuth Reuter, Maynard Meiring, Nelita du Plessis
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247852 (2021)
PLoS ONE
PLoS ONE
Background Inequality is rife throughout South Africa. The first wave of COVID-19 may have affected people in lower socioeconomic groups worse than the affluent. The SARS-CoV-2 seroprevalence and the specificity of anti-SARS-CoV-2 antibody tests in S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75db810a976a6c2d849162aa5cc6871
https://doaj.org/article/8592710943f34ee2bc18bdbe5e341ff5
https://doaj.org/article/8592710943f34ee2bc18bdbe5e341ff5
Publikováno v:
Methods in Molecular Biology ISBN: 9781071610596
The current absence of markers unique to MDSC, particularly those expanded during human infection, necessitate concurrent demonstration of their suppressive capacity to ensure unequivocal identification. This is further complicated by the array of he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89d123cec74eaf522818a5b5dd258a37
https://doi.org/10.1007/978-1-0716-1060-2_12
https://doi.org/10.1007/978-1-0716-1060-2_12
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2236
The current absence of markers unique to MDSC, particularly those expanded during human infection, necessitate concurrent demonstration of their suppressive capacity to ensure unequivocal identification. This is further complicated by the array of he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99f96a04c911601854b65ee1f2805bd8
https://pubmed.ncbi.nlm.nih.gov/33237546
https://pubmed.ncbi.nlm.nih.gov/33237546
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Resistance toward current and new classes of anti-tuberculosis (anti-TB) antibiotics are rapidly emerging; thus, innovative therapies focused on host processes, termed host-directed therapies (HDTs), are promising novel approaches for shortening ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ea93e7dbb917875b12b907e561064d
https://www.frontiersin.org/article/10.3389/fimmu.2020.00451/full
https://www.frontiersin.org/article/10.3389/fimmu.2020.00451/full
Autor:
Zhuo Fang, Nelita du Plessis, Leigh A. Kotze, John T. Belisle, Vinzeigh N. Leukes, Manfred B. Lutz, Bryna L. Fitzgerald, Gerhard Walzl, Andre G. Loxton
Publikováno v:
Cell Immunol
Myeloid-derived suppressor cells (MDSC) are induced during active TB disease to restore immune homeostasis but instead exacerbate disease outcome due to chronic inflammation. Autophagy, in conventional phagocytes, ensures successful clearance of M.tb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b396d56433d98a9bc63116d6e973f0
https://doi.org/10.1016/j.cellimm.2021.104426
https://doi.org/10.1016/j.cellimm.2021.104426
Autor:
Gerhard Walzl, Manfred B. Lutz, Vinzeigh N. Leukes, Leigh A. Kotze, Vini John, Zhuo Fang, Carly Young, Nelita du Plessis
Publikováno v:
EBioMedicine
EBioMedicine, Vol 53, Iss, Pp-(2020)
EBioMedicine, Vol 53, Iss, Pp-(2020)
Mycobacterium tuberculosis (M.tb) is likely the most successful human pathogen, capable of evading protective host immune responses and driving metabolic changes to support its own survival and growth. Ineffective innate and adaptive immune responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26383f6e2344302cc06ec1159e74b48
https://pubmed.ncbi.nlm.nih.gov/32113158
https://pubmed.ncbi.nlm.nih.gov/32113158
Autor:
Nelita du Plessis, Shirley McAnda, Elizna Maasdorp, Stephanus T. Malherbe, Justine Khoury, Anca Dorhoi, Vinzeigh N. Leukes, Gerhard Walzl
Publikováno v:
Cellular immunology
Conventional anti-tuberculosis (TB) therapies comprise lengthy antibiotic treatment regimens, exacerbated by multi-drug resistant and extensively drug resistant mycobacterial strains. We assessed the ability of all-trans retinoic acid (ATRA), as repu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9eafc2ffcffb2126ff689125a16a73
http://europepmc.org/articles/PMC8493473
http://europepmc.org/articles/PMC8493473