Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Vinya Bhuvan"'
Autor:
Eugenia Zah, Eunwoo Nam, Vinya Bhuvan, Uyen Tran, Brenda Y. Ji, Stanley B. Gosliner, Xiuli Wang, Christine E. Brown, Yvonne Y. Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
One cause of relapse in cancer patients treated with chimeric antigen receptor (CAR) T cells is the loss of CAR-targeted antigens, which is particularly common in multiple myeloma (MM). Here the authors engineer a CAR recognizing two common MM-associ
Externí odkaz:
https://doaj.org/article/ec2f088f8b5544bbb62387a290932f01
Autor:
Christine E. Brown, Uyen Tran, Eugenia Zah, Eunwoo Nam, Brenda Y. Ji, Xiuli Wang, Vinya Bhuvan, Yvonne Y. Chen, Stanley B. Gosliner
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Chimeric antigen receptor (CAR)-T cell therapy has shown remarkable clinical efficacy against B-cell malignancies, yet marked vulnerability to antigen escape and tumor relapse exists. Here we report the rational design and optimization of bispecific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c151396e29e87f0556585ecc2e7b36
https://escholarship.org/uc/item/82q2j32v
https://escholarship.org/uc/item/82q2j32v