Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Vinu Krishnan"'
Autor:
Tao Sun, Vinu Krishnan, Daniel C. Pan, Sergey K. Filippov, Sagi Ravid, Apoorva Sarode, Jayoung Kim, Yongzhi Zhang, Chanikarn Power, Sezin Aday, Junling Guo, Jeffrey M. Karp, Nathan J. McDannold, Samir S. Mitragotri
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract Effective chemotherapy delivery for glioblastoma multiforme (GBM) is limited by drug transport across the blood–brain barrier and poor efficacy of single agents. Polymer–drug conjugates can be used to deliver drug combinations with a rat
Externí odkaz:
https://doaj.org/article/d4274d50c9e446f9985d4ad37c66220b
Autor:
Yongsheng Gao, Douglas Vogus, Zongmin Zhao, Wei He, Vinu Krishnan, Jayoung Kim, Yujie Shi, Apoorva Sarode, Anvay Ukidve, Samir Mitragotri
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 1, Pp n/a-n/a (2022)
Abstract Antiproliferative chemotherapeutic agents offer a potential effective treatment for inflammatory arthritis. However, their clinical application is limited by high systemic toxicity, low joint bioavailability as well as formulation challenges
Externí odkaz:
https://doaj.org/article/b1f0cc56376143ffb094a0b755d3ca3d
Autor:
Daniel C. Pan, Vinu Krishnan, Alyssa K. Salinas, Jayoung Kim, Tao Sun, Sagi Ravid, Kevin Peng, Debra Wu, Md Nurunnabi, Jeffery A. Nelson, Zachary Niziolek, Junling Guo, Samir Mitragotri
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 1, Pp n/a-n/a (2021)
Abstract Colorectal cancer, common in both men and women, occurs when tumors form in the linings of the colon. Common treatments of colorectal cancer include surgery, chemotherapy, and radiation therapy; however, many colorectal cancer treatments oft
Externí odkaz:
https://doaj.org/article/66431c8e17534401aed4a237c03882fa
Autor:
Vinu Krishnan, Vimisha Dharamdasani, Shirin Bakre, Ved Dhole, Debra Wu, Bogdan Budnik, Samir Mitragotri
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 466 (2022)
Ratiometric delivery of combination chemotherapy can achieve therapeutic efficacy based on synergistic interactions between drugs. It is critical to design such combinations with drugs that complement each other and reduce cancer growth through multi
Externí odkaz:
https://doaj.org/article/5be87aba328b4b5fb1c169fac1623352
Publikováno v:
Bioengineering & Translational Medicine, Vol 4, Iss 2, Pp n/a-n/a (2019)
Abstract Combination chemotherapy is often employed to improve therapeutic efficacies of drugs. However, traditional combination regimens often utilize drugs at or near‐their maximum tolerated doses (MTDs), elevating the risk of dose‐related toxi
Externí odkaz:
https://doaj.org/article/178251b6f7c841b3a0e0e15ab73669df
Autor:
Debra Wu, Douglas Vogus, Vinu Krishnan, Marta Broto, Anusha Pusuluri, Zongmin Zhao, Neha Kapate, Samir Mitragotri
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 107 (2021)
Liposome-based drug delivery systems have allowed for better drug tolerability and longer circulation times but are often optimized for a single agent due to the inherent difficulty of co-encapsulating two drugs with differing chemical profiles. Here
Externí odkaz:
https://doaj.org/article/c896edbf7469468ead15d9c29c31f4d7
Autor:
Tao Sun, Vinu Krishnan, Daniel C. Pan, Sergey K. Filippov, Sagi Ravid, Apoorva Sarode, Jayoung Kim, Yongzhi Zhang, Chanikarn Power, Sezin Aday, Junling Guo, Jeffrey M. Karp, Nathan J. McDannold, Samir S. Mitragotri
Publikováno v:
Bioengineering & Translational Medicine. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8a8c7e85a5da71488e9127e3f82a218
https://doi.org/10.1002/btm2.10408
https://doi.org/10.1002/btm2.10408
Autor:
Yongsheng Gao, Samir Mitragotri, Vladimir R. Muzykantov, Daniel C. Pan, Zongmin Zhao, Alexandra Fehnel, Abhirup Mandal, Vinu Krishnan, Anvay Ukidve
Publikováno v:
Proc Natl Acad Sci U S A
Erythrocytes naturally capture certain bacterial pathogens in circulation, kill them through oxidative stress, and present them to the antigen-presenting cells (APCs) in the spleen. By leveraging this innate immune function of erythrocytes, we develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068315c0617b67387b843b9bb380b5f2
https://doi.org/10.1073/pnas.2002880117
https://doi.org/10.1073/pnas.2002880117
Autor:
Samir Mitragotri, Vinu Krishnan
Publikováno v:
Advanced Drug Delivery Reviews. 153:87-108
Nanoparticles offer new opportunities for the treatment of skin diseases. The barrier function of the skin poses a significant challenge for nanoparticles to permeate into the tissue, although the barrier is partially compromised in case of injury or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a80f56ff642b084a397cb9af2cd0f33
https://doi.org/10.1016/j.addr.2020.05.011
https://doi.org/10.1016/j.addr.2020.05.011
Autor:
Apoorva Sarode, Zongmin Zhao, Vinu Krishnan, Jayoung Kim, Yujie Shi, Yongsheng Gao, Anvay Ukidve, Douglas R. Vogus, Wei He, Samir Mitragotri
Publikováno v:
Bioengineering & Translational Medicine
Bioengineering & Translational Medicine, Vol 7, Iss 1, Pp n/a-n/a (2022)
Bioengineering & Translational Medicine, Vol 7, Iss 1, Pp n/a-n/a (2022)
Antiproliferative chemotherapeutic agents offer a potential effective treatment for inflammatory arthritis. However, their clinical application is limited by high systemic toxicity, low joint bioavailability as well as formulation challenges. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a767b5f62f8a1b28e9a9cf7c8db2569
http://europepmc.org/articles/PMC8780912
http://europepmc.org/articles/PMC8780912