Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vinothini Subramaniam"'
Autor:
Geik Yong Ang, Choo Yee Yu, Vinothini Subramaniam, Mohd Ikhmal Hanif Abdul Khalid, Tuan Azlin Tuan Abdu Aziz, Richard Johari James, Aminuddin Ahmad, Thuhairah Abdul Rahman, Fadzilah Mohd Nor, Adzrool Idzwan Ismail, Kamarudzaman Md Isa, Hood Salleh, Lay Kek Teh, Mohd Zaki Salleh
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164169 (2016)
The human cytochrome P450 (CYP) is a superfamily of enzymes that have been a focus in research for decades due to their prominent role in drug metabolism. CYP2C is one of the major subfamilies which metabolize more than 10% of all clinically used dru
Externí odkaz:
https://doaj.org/article/48173ba43d3f44ce8ba4565af7cd0318
Autor:
Lay Kek Teh, Aminuddin Ahmad, Vinothini Subramaniam, Thuhairah Hasrah Abdul Rahman, S. Shaari, Choo Yee Yu, Fadzilah Mohd Nor, Mohd Zaki Salleh, Richard Johari James, Geik Yong Ang
Publikováno v:
Genetic Testing and Molecular Biomarkers. 21:409-415
CYP2D6 is one of the major enzymes in the cytochrome P450 monooxygenase system. It metabolizes ∼25% of prescribed drugs and hence, the genetic diversity of a CYP2D6 gene has continued to be of great interest to the medical and pharmaceutical indust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a1793997f99ff761e7702b7d72e5e4
https://doi.org/10.1089/gtmb.2016.0235
https://doi.org/10.1089/gtmb.2016.0235
Autor:
Lay Kek Teh, Vinothini Subramaniam, Tuan Azlin Tuan Abdu Aziz, Lian Shien Lee, Mohamed Izwan Ismail, Choo Yee Yu, Geik Yong Ang, Richard James Johari, Rose Iszati Ismet, Noor Saadah Sahak, Aminuddin Ahmad, Thuhairah Abdul Rahman, Fadzilah Mohd Nor @ Ghazali, SyahrulAzlin Shaari, Mustaffa Omar, Adzrool Idzwan Ismail, Kamarudzaman Md. Isa, Hood Salleh, Mohd Zaki Salleh
Publikováno v:
Drug Metabolism and Pharmacokinetics. 31:304-313
We conducted a systematic characterization of CYP2C9 variants in 61 Orang Asli and 96 Singaporean Malays using the whole genome sequences data and compared the variants with the other 11 HapMap populations. The frequency of rs1057910 (CYP2C9*3) is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281723107751614e00a7b08b8b1c375e
https://doi.org/10.1016/j.dmpk.2016.04.004
https://doi.org/10.1016/j.dmpk.2016.04.004
Autor:
Hood Salleh, Aminuddin Ahmad, Vinothini Subramaniam, Mohd Zaki Salleh, Adzrool Idzwan Ismail, Thuhairah Hasrah Abdul Rahman, Lay Kek Teh, Fadzilah Mohd Nor, Tuan Azlin Tuan Abdu Aziz, Mohd Ikhmal Hanif Abdul Khalid, Richard Johari James, Choo Yee Yu, Geik Yong Ang, Kamarudzaman Md Isa
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164169 (2016)
PLoS ONE
PLoS ONE
The human cytochrome P450 (CYP) is a superfamily of enzymes that have been a focus in research for decades due to their prominent role in drug metabolism. CYP2C is one of the major subfamilies which metabolize more than 10% of all clinically used dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55678dfe6263f5b72777b8ad48ad8a55
https://doi.org/10.1371/journal.pone.0164169
https://doi.org/10.1371/journal.pone.0164169