Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vinoth Sundar Rajan"'
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98034 (2014)
Cancer metastasis is a complex process involving cell-cell interactions mediated by cell adhesive molecules. In this study we determine the adhesion strength between an endothelial cell monolayer and tumor cells of different metastatic potentials usi
Externí odkaz:
https://doaj.org/article/f14fbf37482c4bf9bdc0a13e554a1aad
Autor:
L. Marcus Wilhelmsson, Yii-Lih Lin, Felix Ritort, Uttama Dutta, Fredrik Westerlund, Xavier Viader-Godoy, Vinoth Sundar Rajan
Publikováno v:
Physical Chemistry Chemical Physics
We use mechanical unfolding of single DNA hairpins with modified bases to accurately assess intra- and intermolecular forces in nucleic acids. As expected, the modification stabilizes the hybridized hairpin, but we also observe intriguing stacking in
Autor:
Pauline Pfeiffer, Tom Brown, Jesper R. Nilsson, Anders Dahlén, Mattias Bood, Anders Foller Füchtbauer, Marcus Wilhelmsson, Afaf H. El-Sagheer, Anna Wiktoria Wypijewska Del Nogal, Vinoth Sundar Rajan, Sangamesh Sarangamath, Morten Grøtli, Moa Sandberg Wranne
Publikováno v:
Nucleic Acids Research
With the central role of nucleic acids there is a need for development of fluorophores that facilitate the visualization of processes involving nucleic acids without perturbing their natural properties and behaviour. Here, we incorporate a new analog
Autor:
Vinoth Sundar Rajan, Anna Wiktoria Wypijewska Del Nogal, Marcus Wilhelmsson, Fredrik Westerlund
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 9008, p 9008 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 9008, p 9008 (2021)
Pre-miRNA-377 is a hairpin-shaped regulatory RNA associated with heart failure. Here, we use single-molecule optical tweezers to unzip pre-miRNA-377 and study its stability and dynamics. We show that magnesium ions have a strong stabilizing effect, a
Autor:
Elvira Infante, Yongjian Wang, Catherine M. Shanahan, Stephanie Board, Andrew Stannard, Samuel A. Gulaidi Breen, Ainhoa Lezamiz, Palma Rico-Lastres, Fani Panagaki, Vinoth Sundar Rajan, Elena Rostkova, Pere Roca-Cusachs, Sergi Garcia-Manyes, Amy E. M. Beedle
Publikováno v:
Infante, E, Stannard, A, Board, S J, Rico-Lastres, P, Rostkova, E, Beedle, A E M, Lezamiz, A, Wang, Y J, Gulaidi Breen, S, Panagaki, F, Sundar Rajan, V, Shanahan, C, Roca-Cusachs, P & Garcia-Manyes, S 2019, ' The mechanical stability of proteins regulates their translocation rate into the cell nucleus ', Nature Physics, vol. 15, no. 9, pp. 973-981 . https://doi.org/10.1038/s41567-019-0551-3
Publons
Nature Physics
Publons
Nature Physics
A cell’s ability to react to mechanical stimuli is known to be affected by the transport of transcription factors, the proteins responsible for regulating transcription of DNA into RNA, across the membrane enveloping its nucleus. Yet the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c515c138bed1ed5dac5723562d2c70
https://kclpure.kcl.ac.uk/ws/files/113466324/The_mechanical_stability_of_INFANTE_Published_1_July_2019_GREEEN_AAM.pdf
https://kclpure.kcl.ac.uk/ws/files/113466324/The_mechanical_stability_of_INFANTE_Published_1_July_2019_GREEEN_AAM.pdf
Publikováno v:
Biophysical Journal
Biophysical Journal, Biophysical Society, 2017, 112 (6), pp.1246-1257. ⟨10.1016/j.bpj.2017.01.033⟩
Biophysical Journal, 2017, 112 (6), pp.1246-1257. ⟨10.1016/j.bpj.2017.01.033⟩
Biophysical Journal, Biophysical Society, 2017, 112 (6), pp.1246-1257. ⟨10.1016/j.bpj.2017.01.033⟩
Biophysical Journal, 2017, 112 (6), pp.1246-1257. ⟨10.1016/j.bpj.2017.01.033⟩
International audience; Adhesion of cancer cells to endothelial cells is a key step in cancer metastasis; therefore, identifying the key molecules involved during this process promises to aid in efforts to block the metastatic cascade. We have previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4893f5a7dbd09fd4a83e178378fef013
https://www.hal.inserm.fr/inserm-01498619/file/Manuscript_BiophysJ_V-Sundar_2017.pdf
https://www.hal.inserm.fr/inserm-01498619/file/Manuscript_BiophysJ_V-Sundar_2017.pdf
Publikováno v:
PLoS ONE
PLoS ONE, 2014, 9 (5), pp.e98034
PLoS ONE, Public Library of Science, 2014, 9 (5), pp.e98034
PLoS ONE, Vol 9, Iss 5, p e98034 (2014)
PLoS ONE, 2014, 9 (5), pp.e98034
PLoS ONE, Public Library of Science, 2014, 9 (5), pp.e98034
PLoS ONE, Vol 9, Iss 5, p e98034 (2014)
International audience; Cancer metastasis is a complex process involving cell-cell interactions mediated by cell adhesive molecules. In this study we determine the adhesion strength between an endothelial cell monolayer and tumor cells of different m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef7e3c747789c37da56b8035a5a0e5a
https://hal.science/hal-00993484
https://hal.science/hal-00993484
Publikováno v:
Biomedical Optics Express
3D STORM is one of the leading methods for super-resolution imaging, with resolution down to 10 nm in the lateral direction, and 30–50 nm in the axial direction. However, there is one important requirement to perform this type of imaging: making dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ee38bb1579e9b1663d51d366a8870c
https://infoscience.epfl.ch/record/187186
https://infoscience.epfl.ch/record/187186