Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Vinodkumar B. Pillai"'
Publikováno v:
JCSM Rapid Communications, Vol 4, Iss 1, Pp 40-56 (2021)
Abstract Background During cancer cachexia, cytokines released from tumour cells can alter body's metabolism, which can lead to onset of this disease process. Biological basis of cachexia is multifactorial; hence, it is important to identify and modu
Externí odkaz:
https://doaj.org/article/076f565bb6b84cf8acb966a6bb27a6b6
Publikováno v:
Aging (Albany NY)
Sirtuins have been shown to regulate the aging process. We have previously demonstrated that Sirt6 blocks the pressure overload-induced cardiac hypertrophy in mice. Here, we show that Sirt6 can also mitigate aging-induced cardiomyocyte senescence and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08fc2306c5f6aacd1e724e4f7db6a522
https://doi.org/10.18632/aging.203027
https://doi.org/10.18632/aging.203027
Autor:
Mahesh P. Gupta, Vinodkumar B. Pillai
Publikováno v:
Am J Physiol Endocrinol Metab
The ability to ward off pathogens with minimal damage to the host determines the immune system's robustness. Multiple factors, including pathogen processing, identification, secretion of mediator and effector molecules, and immune cell proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332457ec509d16b18ef238809b51f2be
https://doi.org/10.1152/ajpendo.00483.2020
https://doi.org/10.1152/ajpendo.00483.2020
Publikováno v:
Jcsm Rapid Communications
JCSM Rapid Communications, Vol 4, Iss 1, Pp 40-56 (2021)
JCSM Rapid Communications, Vol 4, Iss 1, Pp 40-56 (2021)
Background During cancer cachexia, cytokines released from tumour cells can alter body's metabolism, which can lead to onset of this disease process. Biological basis of cachexia is multifactorial; hence, it is important to identify and modulate mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56895eb47c68db2d0e83218622805ba9
http://europepmc.org/articles/PMC8237231
http://europepmc.org/articles/PMC8237231
Autor:
Willard W. Sharp, Sadhana Samant, Abhinav Kanwal, Jack L. Arbiser, Vinodkumar B. Pillai, Mahesh P. Gupta, Yong Hu Fang
Publikováno v:
Oncotarget
// Vinodkumar B. Pillai 1 , Abhinav Kanwal 1 , Yong Hu Fang 2 , Willard W. Sharp 2 , Sadhana Samant 1 , Jack Arbiser 3 and Mahesh P. Gupta 1 1 Department of Surgery, Pritzker School of Medicine, University of Chicago, Chicago, IL, USA 2 Department of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7bb63eba9972a625f658d4c16faa62
http://europepmc.org/articles/PMC5470953
http://europepmc.org/articles/PMC5470953
Publikováno v:
FASEB J
Sirtuins (Sirts) are implicated in regulating a myriad of biologic functions ranging from cell growth and metabolism to longevity. Here, we show that nuclear Sirt, Sirt6, and mitochondrial Sirt, Sirt3, regulate each other’s activity and protect the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5695073c80575520797e17894dc436ba
https://pubmed.ncbi.nlm.nih.gov/33373167
https://pubmed.ncbi.nlm.nih.gov/33373167
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d05718340a655d611398882ae417f5d3
https://doi.org/10.1096/fasebj.2019.33.1_supplement.700.11
https://doi.org/10.1096/fasebj.2019.33.1_supplement.700.11
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::773f251d6afe807d24f0e28aeb3e31a4
https://doi.org/10.1096/fasebj.2019.33.1_supplement.693.7
https://doi.org/10.1096/fasebj.2019.33.1_supplement.693.7
Publikováno v:
Trends in Endocrinology & Metabolism. 27:563-573
Cardiovascular diseases (CVDs) are expanding at an alarming rate and people's propensity to develop them increases with age. Growing evidence indicates that sirtuins play a pivotal role in regulating a multitude of age-related diseases. Sirtuins are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b6b1a371c1cfb9b1206cc244b4ddd29
https://doi.org/10.1016/j.tem.2016.04.015
https://doi.org/10.1016/j.tem.2016.04.015
Autor:
Jing-Yi Huang, Raghu S. Nagalingam, Madhu Gupta, Sadhana Samant, Donald Wolfgeher, Samik Bindu, Mahesh P. Gupta, Eric Verdin, Nagalingam R. Sundaresan, Yong Pan, Vinodkumar B. Pillai
Publikováno v:
Molecular and Cellular Biology. 36:678-692
Tissue fibrosis is a major cause of organ dysfunction during chronic diseases and aging. A critical step in this process is transforming growth factor β1 (TGF-β1)-mediated transformation of fibroblasts into myofibroblasts, cells capable of synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf69c4408e773e865085ae1c7bc1e82
https://doi.org/10.1128/mcb.00586-15
https://doi.org/10.1128/mcb.00586-15