Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Vinodh Saravanakumar"'
Autor:
Pragya Gupta, Sangam Giri Goswami, Geeta Kumari, Vinodh Saravanakumar, Nupur Bhargava, Akhila Balakrishna Rai, Praveen Singh, Rahul C. Bhoyar, V. R. Arvinden, Padma Gunda, Suman Jain, Vanya Kadla Narayana, Sayali C. Deolankar, T. S. Keshava Prasad, Vivek T. Natarajan, Vinod Scaria, Shailja Singh, Sivaprakash Ramalingam
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Ex vivo cellular system that accurately replicates sickle cell disease and β-thalassemia characteristics is a highly sought-after goal in the field of erythroid biology. In this study, we present the generation of erythroid progenitor lines
Externí odkaz:
https://doaj.org/article/057cee76498e45b68c0e7b95f3a332c8
Autor:
Pragya Gupta, V. R. Arvinden, Priya Thakur, Rahul C. Bhoyar, Vinodh Saravanakumar, Narendra Varma Gottumukkala, Sangam Giri Goswami, Mehwish Nafiz, Aditya Ramdas Iyer, Harie Vignesh, Rajat Soni, Nupur Bhargava, Padma Gunda, Suman Jain, Vivek Gupta, Sridhar Sivasubbu, Vinod Scaria, Sivaprakash Ramalingam
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
β-hemoglobinopathies such as β-thalassemia (BT) and Sickle cell disease (SCD) are inherited monogenic blood disorders with significant global burden. Hence, early and affordable diagnosis can alleviate morbidity and reduce mortality given the lack
Externí odkaz:
https://doaj.org/article/a6cb5d12882b4757acc144143da96ca8
Autor:
Priya Thakur, Pragya Gupta, Nupur Bhargava, Rajat Soni, Narendra Varma Gottumukkala, Sangam Giri Goswami, Gaurav Kharya, Vinodh Saravanakumar, Padma Gunda, Suman Jain, Jasmita Dass, Mukul Aggarwal, Sivaprakash Ramalingam
Publikováno v:
Diagnostics, Vol 12, Iss 7, p 1765 (2022)
Sickle cell disease (SCD) is the most prevalent life-threatening blood monogenic disorder. Currently, there is no cure available, apart from bone marrow transplantation. Early and efficient diagnosis of SCD is key to disease management, which would m
Externí odkaz:
https://doaj.org/article/53809a58ee74487d832c6189943ff76d
Autor:
Nupur Bhargava, Priya Thakur, Thulasi Priyadharshini Muruganandam, Shashank Jaitly, Pragya Gupta, Neelam Lohani, Sangam Giri Goswami, Vinodh Saravanakumar, Saurabh Kumar Bhattacharya, Suman Jain, Sivaprakash Ramalingam
Publikováno v:
Molecular Biology Reports. 49:7887-7898
Disease-specific human induced pluripotent stem cells (hiPSCs) can be generated directly from individuals with known disease characteristics or alternatively be modified using genome editing approaches to introduce disease causing genetic mutations t
Autor:
Priya Thakur, Pragya Gupta, Nupur Bhargava, Rajat Soni, Narendra Verma, Sangam Giri Goswami, Gaurav Kharya, Vinodh Saravanakumar, Padma G, Suman Jain, Jasmita Dass, Mukul Aggarwal, Sivaprakash Ramalingam
Sickle cell disease (SCD) is the most prevalent life threatening blood monogenic disorder. Currently, there is no cure available, apart from bone marrow transplantation. Early and efficient diagnosis of SCD is key to disease management which would ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4251e159536cbd95594d000428f5db78
https://doi.org/10.1101/2022.06.14.22276141
https://doi.org/10.1101/2022.06.14.22276141