Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Vinod Yadav Yadav"'
Autor:
Natalia Reszka-Blanco, Megan Krumpoch, Michaela Mentzer, Vinod Yadav Yadav, Brianna Bannister, Dan Cui, Elizabeth Konopka, Dooyoung Lee, Fu-Yang Lin, Terence Moy, Eugene Nebelitsky, Qi Qiao, Inese Smutske, Charlotte Root, Patrick Allison, Sarah Krueger, Dawn Troast, Blaise Lippa, Bruce Rogers, Adrian Ray
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/812828d9a448449798137bb0777953c2
Autor:
Dooyoung Lee, Terence Moy, Natalia J. Reszka-Blanco, Patrick Allison, Lippa Blaise S, Dan Cui, Sarah Krueger, Adrian S. Ray, Brianna Bannister, Rogers Bruce N, Michaela Mentzer, Megan Krumpoch, Qi Qiao, Eugene Nebelitsky, Fu-Yang Lin, Troast Dawn M, Charlotte Root, Elizabeth Konopka, Inese Smutske, Vinod Yadav Yadav
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundIntegrin αvβ8 activates TGFβ in immune cells. αvβ8 inhibitors have been shown to potentiate immune checkpoint blockade (ICB) in preclinical models [1]. Radioimmunotherapy (RIT) induces immunogenic cell death and antigen presentation, h
Autor:
Adrian S. Ray, Troast Dawn M, James E. Dowling, Vinod Yadav Yadav, Eugene Nebelitsky, Lippa Blaise S, Andrew K. Sullivan, Fu-Yang Lin, Dan Cui, Dooyoung Lee, Lia Luus, Megan Krumpoch, Laura Cappellucci, Terence Moy, Bryce Alden Harrison, Rogers Bruce N, Natalia J. Reszka-Blanco, Meghan Monroy, Qi Qiao, Elizabeth Gwara
Publikováno v:
Cancer Research. 81:1559-1559
Introduction We explored whether integrin αvβ8 inhibition potentiates immune checkpoint blockade (ICB) in syngeneic orthotopic models of breast cancer. Integrin αvβ8 mediates cell type specific and tissue localized activation of TGFβ1/3 to regul