Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Vinod Vijayakurup"'
2
Akademický článek
Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival
Autor: Vinod Vijayakurup, Kyungah Maeng, Hye Seung Lee, Benjamin Meyer, Sandra Burkett, Akbar Nawab, Michael W. Dougherty, Christian Jobin, Iqbal Mahmud, Timothy J. Garrett, Michael Feely, Kyoung Bun Lee, Frederic J. Kaye, Maria V. Guijarro, Maria Zajac-Kaye
Publikováno v: JCI Insight, Vol 7, Iss 19 (2022)
Clinical studies of cancer patients have shown that overexpression or amplification of thymidylate synthase (TS) correlates with a worse clinical outcome. We previously showed that elevated TS exhibits properties of an oncogene and promotes pancreati
Externí odkaz: https://doaj.org/article/c4d8ea92daf8429f8458305e8f8361ea
Zobrazit plný text záznamu
4
Akademický článek
Blockade of Uttroside B-Induced Autophagic Pro-Survival Signals Augments Its Chemotherapeutic Efficacy Against Hepatocellular Carcinoma
Autor: Lekshmi R. Nath, Mundanattu Swetha, Vinod Vijayakurup, Arun Kumar Thangarasu, Nair Hariprasad Haritha, Anwar Shabna, Sreekumar U. Aiswarya, Tennyson P. Rayginia, C. K. Keerthana, Kalishwaralal Kalimuthu, Sankar Sundaram, Ravi Shankar Lankalapalli, Sreekumar Pillai, Rheal Towner, Noah Isakov, Ruby John Anto
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
Our previous study has demonstrated that Uttroside B (Utt-B), a saponin isolated from the leaves of Solanum nigrum Linn induces apoptosis in hepatic cancer cells and exhibits a remarkable growth inhibition of Hepatocellular Carcinoma (HCC). Our innov
Externí odkaz: https://doaj.org/article/27412c60fb1542d8b30f7778ed53e63b
Zobrazit plný text záznamu
5
Akademický článek
Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy
Autor: Nair Hariprasad Haritha, Akbar Nawab, Vinod Vijayakurup, Nikhil Ponnoor Anto, Vijayasteltar B. Liju, Vijai V. Alex, Areekkara Nisthul Amrutha, Sreekumar U. Aiswarya, Mundanattu Swetha, Balachandran S. Vinod, Sankar Sundaram, Maria V. Guijarro, Thomas Herlevich, Archana Krishna, Nesteena K. Nestory, Smitha V. Bava, Chittalakkottu Sadasivan, Maria Zajac-Kaye, Ruby John Anto
Publikováno v: Frontiers in Oncology, Vol 11 (2021)
BackgroundThe ongoing treatment modalities for breast cancer (BC) primarily rely on the expression status of ER, PR and HER-2 receptors in BC tissues. Our strategy of chemosensitization provides new insights to counter chemoresistance, a major obstac
Externí odkaz: https://doaj.org/article/98aa0d851ca44ca187bf9bcc4a9ba983
Zobrazit plný text záznamu
9
High LC3/Beclin Expression Correlates with Poor Survival in Glioma: a Definitive Role for Autophagy as Evidenced by In Vitro Autophagic Flux
Autor: Srinivas Gopala, Easwer Hv, Padmakrishnan Cj, Girish Menon, Suresh Nair, Vinod Vijayakurup
Publikováno v: Pathology & Oncology Research. 25:137-148
Recent studies suggest the role of autophagy, an evolutionarily conserved catabolic process, in determining the response of gliomas to treatment either positively or negatively. The study attempts to characterize autophagy in low and high-grade gliom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79206cfbff56dc11f57abc469ba4d515
https://doi.org/10.1007/s12253-017-0310-7
Zobrazit plný text záznamu
10
Chitosan Encapsulation Enhances the Bioavailability and Tissue Retention of Curcumin and Improves its Efficacy in Preventing B[a]P-induced Lung Carcinogenesis
Autor: Mohan Shankar G, C. Devika Nandan, Archana P. Retnakumari, Vinod Vijayakurup, Jannet Somaraj, Balachandran S Vinod, Jayesh Antony, Arun Kumar T. Thulasidasan, Vijayasteltar Belsamma Liju, G. S. Vinod Kumar, Ruby John Anto, Sankar Sundaram, Vijai V. Alex
Publikováno v: Cancer prevention research (Philadelphia, Pa.). 12(4)
The rate of lung cancer incidence is alarmingly mounting, despite the decline of smoking and tobacco consumption. Recent reports indicate a very high correlation between the growing fast food culture and lung cancer incidence. Benzo[a]pyrene (B[a]P)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fcc9db4abf2212ee73d53e03d6d76e
https://pubmed.ncbi.nlm.nih.gov/30760502
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje