Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vinod S. Ramgolam"'
Autor:
Nicholas S. Wilcox, Timur O. Yarovinsky, Prakruti Pandya, Vinod S. Ramgolam, Albertomaria Moro, Yinyu Wu, Stefania Nicoli, Karen K. Hirschi, Jeffrey R. Bender
Publikováno v:
iScience, Vol 26, Iss 12, Pp 107985- (2023)
Summary: Tissue resident macrophages are largely of embryonic (fetal liver) origin and long-lived, while bone marrow–derived macrophages (BMDM) are recruited following an acute perturbation, such as hypoxia in the setting of myocardial ischemia. Pr
Externí odkaz:
https://doaj.org/article/9e5e710e290d45e49a4b6036fefe5318
Autor:
Gautham K Rao, Albert Wong, Mark Collinge, Joseph Sarhan, Timur O Yarovinsky, Vinod S Ramgolam, Matthias Gaestel, Ruggero Pardi, Jeffrey R Bender
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201103 (2018)
Activation of the β2 integrin lymphocyte function-associated antigen-1 (LFA-1) in T cells induces stabilization of proinflammatory AU-rich element (ARE)-bearing mRNAs, by triggering the nuclear-to-cytoplasmic translocation of the mRNA-binding and -s
Externí odkaz:
https://doaj.org/article/ad94a9ab4fcd48998eec75084a4ab756
Autor:
Stefania Nicoli, Karen K. Hirschi, Timur O. Yarovinsky, Nicholas S. Wilcox, Prakruti Pandya, Jeffrey R. Bender, Vinod S. Ramgolam, Yinyu Wu, Albertomaria Moro
SummaryTissue homeostasis and repair are orchestrated by resident and newly recruited macrophages that alter their gene expression program in response to changes in tissue microenvironment. Embryonic macrophages, such as fetal liver derived macrophag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4118e3de96ca546fcc326fa635177809
https://doi.org/10.1101/2021.03.18.435732
https://doi.org/10.1101/2021.03.18.435732
Autor:
Vinod S Ramgolam, Scott D DeGregorio, Gautham K Rao, Mark Collinge, Sharmila S Subaran, Silva Markovic-Plese, Ruggero Pardi, Jeffrey R Bender
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14450 (2010)
Engagement of the β2 integrin, lymphocyte function-associated antigen-1 (LFA-1), results in stabilization of T cell mRNA transcripts containing AU-rich elements (AREs) by inducing rapid nuclear-to-cytosolic translocation of the RNA-stabilizing prote
Externí odkaz:
https://doaj.org/article/b1333a88b8084887a439447563f996ee
Publikováno v:
Journal of Signal Transduction
Multiple sclerosis (MS) is an inflammatory demyelinating, presumably autoimmune disease of the central nervous system (CNS). Among the available MS therapies, interferon (IFN)βand the recently introduced statins have been reported to exert their imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce8a3ceb58e65341897e4e22b16cbe8
https://doi.org/10.1155/2011/635721
https://doi.org/10.1155/2011/635721
Autor:
Matthias Gaestel, Ruggero Pardi, Joseph Sarhan, Jeffrey R. Bender, Vinod S. Ramgolam, Timur O. Yarovinsky, Mark Collinge, Albert J. Wong, Gautham K. Rao
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201103 (2018)
PLoS ONE
PLoS ONE
Activation of the β2 integrin lymphocyte function-associated antigen-1 (LFA-1) in T cells induces stabilization of proinflammatory AU-rich element (ARE)-bearing mRNAs, by triggering the nuclear-to-cytoplasmic translocation of the mRNA-binding and -s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5032ce8b2748c6ec3f5feb069062113d
https://doi.org/10.1371/journal.pone.0201103
https://doi.org/10.1371/journal.pone.0201103
Publikováno v:
The Journal of Immunology. 180:6988-6996
Statins, extensively used as cholesterol-lowering agents, have recently been identified as immunomodulatory agents. This study investigated the statins’ mechanisms that target the autoimmune response in humans, and evaluated their therapeutic poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77c6afa9eb2723440d6639309cbf612
https://doi.org/10.4049/jimmunol.180.10.6988
https://doi.org/10.4049/jimmunol.180.10.6988
Publikováno v:
Drug Discovery Today: Disease Mechanisms. 2:77-84
Mechanisms have been identified by which the vasculature modifies lipids into an atherogenic form, with those modified lipids in turn activating vascular and immune cells, initiating self-perpetuating cycles of inflammation and lipid alteration that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::813ebf6fabdae9a47582718adfd70f18
https://doi.org/10.1016/j.ddmec.2005.05.010
https://doi.org/10.1016/j.ddmec.2005.05.010
Autor:
Yonggang Sha, Manisha Chopra, Karen L. Marcus, Neelima Choudhary, Vinod S. Ramgolam, Luigi Troiani, Silva Markovic-Plese
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 186(7)
IFN-β-1b is a first-line immunomodulatory therapy for relapsing–remitting multiple sclerosis (RR MS). However, its effects on B cells have not been characterized. In vitro studies of B cells derived from RR MS patients revealed that IFN-β-1b decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52642f36c3982c7375fcc509c8dee294
https://pubmed.ncbi.nlm.nih.gov/21368231
https://pubmed.ncbi.nlm.nih.gov/21368231
Publikováno v:
Endocrine, metabolicimmune disorders drug targets. 10(2)
Interferon-beta (IFNbeta) has been used over the past 15 years as a first-line therapy for relapsing remitting multiple sclerosis (RR MS), however its mechanisms of action are still not completely elucidated. Recently discovered Th17 cells have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef1374bdd20438fa972c18b4da64fbb
https://pubmed.ncbi.nlm.nih.gov/20384573
https://pubmed.ncbi.nlm.nih.gov/20384573