Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Vinod K. Ahirrao"'
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Akademický článek
Time-dependent selected reaction monitoring-based GC-MS/MS method for estimation of genotoxic impurities in new antibacterial agent: alalevonadifloxacin mesylate
Autor: Vinod K. Ahirrao, Rajiv A. Jadhav, Vipul P. Rane, Harshal R. Bhamare, Ravindra D. Yeole
Publikováno v: Journal of Analytical Science and Technology, Vol 11, Iss 1, Pp 1-9 (2020)
Abstract Alalevonadifloxacin mesylate (ALA), pro-drug of levonadifloxacin is a new antibiotic approved in India to treat infections caused by Gram-positive bacteria. Alkyl mesylates (AMs) are known genotoxic impurities (GTI’s) formed in drug substa
Externí odkaz: https://doaj.org/article/3eb5d9728342463e962ab0b796486c24
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4
Impurity Profiling of Novel Oxazolidinone Antibacterial Agent: WCK 4086
Autor: Vinod K. Ahirrao, Rushikesh H. Patil, Vipul P. Rane, Kiran R. Patil, Ravindra D. Yeole, Amin R. Pathan
Publikováno v: Chromatographia. 84:1121-1130
WCK 4086 is new antibacterial drug being developed to treat infections caused by Gram positive bacteria. This study describes development of mass spectrometry (MS) compatible reversed phase liquid chromatographic method for separation, identification
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::949f6e62fabddf0c3fb3864f46be159d
https://doi.org/10.1007/s10337-021-04095-y
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5
Impurity Profiling of a Novel Anti-MRSA Antibacterial Drug: Alalevonadifloxacin
Autor: Vipul P. Rane, Ravindra D. Yeole, Kiran R. Patil, Vinod K. Ahirrao
Publikováno v: Journal of Chromatographic Science. 58:951-960
Alalevonadifloxacin (ALA, formerly described as WCK 2349) is a novel antibacterial drug developed to treat infections caused by Gram-positive bacteria. The current study was aimed to identify and quantify impurities in ALA. Mass spectrometry (MS) com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af6d893f8679c8781d0d34bd127b277
https://doi.org/10.1093/chromsci/bmaa068
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6
An Efficient HPLC–MS Method for Impurity Profile of Ertapenem
Autor: Vipul P. Rane, Rajiv A. Jadhav, Amin R. Pathan, Ravindra D. Yeole, Kiran R. Patil, Vinod K. Ahirrao
Publikováno v: Chromatographia. 83:1095-1105
A mass spectrometer compatible, reverse-phase high-performance liquid chromatography method capable to resolve twenty-six impurities and degradation products (DPs) in Ertapenem (ERT) has been developed. Eight dimer impurities (m/z 951) and two dehydr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ac76a3e39cd2bd849fa3f895981aaf3
https://doi.org/10.1007/s10337-020-03928-6
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7
Time-dependent selected reaction monitoring-based GC-MS/MS method for estimation of genotoxic impurities in new antibacterial agent: alalevonadifloxacin mesylate
Autor: Harshal R. Bhamare, Vinod K. Ahirrao, Vipul P. Rane, Ravindra D. Yeole, Rajiv A. Jadhav
Publikováno v: Journal of Analytical Science and Technology, Vol 11, Iss 1, Pp 1-9 (2020)
Alalevonadifloxacin mesylate (ALA), pro-drug of levonadifloxacin is a new antibiotic approved in India to treat infections caused by Gram-positive bacteria. Alkyl mesylates (AMs) are known genotoxic impurities (GTI’s) formed in drug substances isol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6dcbb32baf8a7772b8ceca0ee79219b
http://link.springer.com/article/10.1186/s40543-020-00214-w
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8
Impurity Profiling of a Novel β-Lactam Enhancer: Zidebactam
Autor: Vinod K. Ahirrao, Vipul P. Rane, Kiran R. Patil, Rajiv A. Jadhav, Ravindra D. Yeole
Publikováno v: Chromatographia. 83:423-437
Zidebactam (ZID) is a novel drug in clinical development; it potentiates the antibacterial activity of β-lactam antibiotics. Two reversed phase liquid chromatographic (RP-LC) methods were developed for ZID; a mass spectrometer (MS) compatible method
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb76838fc80d1d54ac4e0393832b1333
https://doi.org/10.1007/s10337-019-03845-3
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9
Identification of Monomethyl Sulfate and Sulfate Impurities in Zidebactam Using LC–MS and Application of Mixed-Mode Liquid Chromatography with Charged Aerosol Detection and Ion Chromatography for Quantification
Autor: Kiran R. Patil, Vipul P. Rane, Vijay S. Bhamare, Vinod K. Ahirrao, Ravindra D. Yeole, Rajiv A. Jadhav, Dharamvir S. Yadav
Publikováno v: Chromatographia. 83:219-228
Zidebactam (ZID), a novel β-lactam enhancer drug being developed to treat infections caused by Gram-negative bacteria, currently is in phase III clinical development. Two ionic impurities observed in liquid chromatography with charged aerosol detect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3973595e4d487f1c98434df98ff4b4ff
https://doi.org/10.1007/s10337-019-03836-4
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10
Liquid Chromatographic Separation and Thermodynamic Investigation of Ethyl Nipecotate Enantiomers on Immobilized Amylose-Based Chiral Stationary Phase
Autor: Arjun B Jadhav, Vipul P. Rane, Ravindra D. Yeole, Kiran R. Patil, Vinod K. Ahirrao, Kiran B More
Publikováno v: Journal of Chromatographic Science. 57:815-820
Ethyl nipecotate enantiomers are widely used as chiral building blocks in the synthesis of drug substances. An efficient and economic chiral high-performance liquid chromatographic method for determination of enantiomeric purity of ethyl nipecotate i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4934db4143ab7ba7e945b31b72043a66
https://doi.org/10.1093/chromsci/bmz065
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