Zobrazeno 1 - 10 of 436 pro vyhledávání: '"Vinod, Subramaniam"'
1
Akademický článek
How important is the N-terminal acetylation of alpha-synuclein for its function and aggregation into amyloids?
Autor: Aditya Iyer, Arshdeep Sidhu, Vinod Subramaniam
Publikováno v: Frontiers in Neuroscience, Vol 16 (2022)
N-α-acetylation is a frequently occurring post-translational modification in eukaryotic proteins. It has manifold physiological consequences on the regulation and function of several proteins, with emerging studies suggesting that it is a global reg
Externí odkaz: https://doaj.org/article/1ddb08617bef4ca19d9588ca67d9fd98
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2
Akademický článek
Non-uniform self-assembly: On the anisotropic architecture of α-synuclein supra-fibrillar aggregates
Autor: Slav A. Semerdzhiev, Volodymyr V. Shvadchak, Vinod Subramaniam, Mireille M. A. E. Claessens
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Although the function of biopolymer hydrogels in nature depends on structural anisotropy at mesoscopic length scales, the self-assembly of such anisotropic structures in vitro is challenging. Here we show that fibrils of the protein α-synuc
Externí odkaz: https://doaj.org/article/1596bfc132534431bae186e64f01ebf2
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3
Akademický článek
Supporting data of spatiotemporal proliferation of human stromal cells adjusts to nutrient availability and leads to stanniocalcin-1 expression in vitro and in vivo
Autor: Gustavo A. Higuera, Hugo Fernandes, Tim W.G.M. Spitters, Jeroen van de Peppel, Nils Aufferman, Roman Truckenmueller, Maryana Escalante, Reinout Stoop, Johannes P van Leeuwen, Jan de Boer, Vinod Subramaniam, Marcel Karperien, Clemens van Blitterswijk, Anton van Boxtel, Lorenzo Moroni
Publikováno v: Data in Brief, Vol 5, Iss C, Pp 84-94 (2015)
This data article contains seven figures and two tables supporting the research article entitled: spatiotemporal proliferation of human stromal cells adjusts to nutrient availability and leads to stanniocalcin-1 expression in vitro and in vivo [1]. T
Externí odkaz: https://doaj.org/article/4ebcdc6a2f7e428abdf4344794dfe859
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4
Akademický článek
Direct Observation of α-Synuclein Amyloid Aggregates in Endocytic Vesicles of Neuroblastoma Cells.
Autor: Mihaela M Apetri, Rolf Harkes, Vinod Subramaniam, Gerard W Canters, Thomas Schmidt, Thijs J Aartsma
Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0153020 (2016)
Aggregation of α-synuclein has been linked to both familial and sporadic Parkinson's disease. Recent studies suggest that α-synuclein aggregates may spread from cell to cell and raise questions about the propagation of neurodegeneration. While cont
Externí odkaz: https://doaj.org/article/1a54ddfcb0ec41d7888d3f41e5d88474
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5
Akademický článek
p53 Specifically Binds Triplex DNA In Vitro and in Cells.
Autor: Marie Brázdová, Vlastimil Tichý, Robert Helma, Pavla Bažantová, Alena Polášková, Aneta Krejčí, Marek Petr, Lucie Navrátilová, Olga Tichá, Karel Nejedlý, Martin L Bennink, Vinod Subramaniam, Zuzana Bábková, Tomáš Martínek, Matej Lexa, Matej Adámik
Publikováno v: PLoS ONE, Vol 11, Iss 12, p e0167439 (2016)
Triplex DNA is implicated in a wide range of biological activities, including regulation of gene expression and genomic instability leading to cancer. The tumor suppressor p53 is a central regulator of cell fate in response to different type of insul
Externí odkaz: https://doaj.org/article/b3f101886c88485e8b58765be1c7d627
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6
Quantitative Determination of Dark Chromophore Population Explains the Apparent Low Quantum Yield of Red Fluorescent Proteins
Autor: Laura van Weeren, Christian Blum, Jente Stouthamer, Daphne S. Bindels, Vinod Subramaniam, Theodorus W. J. Gadella, Jord C. Prangsma, Robert Molenaar, Lindsay Haarbosch, Willem L. Vos
Publikováno v: The journal of Physical Chemistry. B, 124(8), 1383-1391. American Chemical Society
The Journal of physical chemistry B, 124(8), 1383-1391. American Chemical Society
The Journal of Physical Chemistry. B
The fluorescence quantum yield of four representative red fluorescent proteins mCherry, mKate2, mRuby2, and the recently introduced mScarlet was investigated. The excited state lifetimes were measured as a function of the distance to a gold mirror in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad0e66dc22d8c7cbe52819b9650c8bc
https://doi.org/10.1021/acs.jpcb.9b10396
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7
Akademický článek
Room temperature excitation spectroscopy of single quantum dots
Autor: Christian Blum, Frank Schleifenbaum, Martijn Stopel, Sébastien Peter, Marcus Sackrow, Vinod Subramaniam, Alfred J. Meixner
Publikováno v: Beilstein Journal of Nanotechnology, Vol 2, Iss 1, Pp 516-524 (2011)
We report a single molecule detection scheme to investigate excitation spectra of single emitters at room temperature. We demonstrate the potential of single emitter photoluminescence excitation spectroscopy by recording excitation spectra of single
Externí odkaz: https://doaj.org/article/198dae9cf9834a5383a5eef71a29a102
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9
Akademický článek
Parkinson's Protein α-Synuclein Binds Efficiently and with a Novel Conformation to Two Natural Membrane Mimics.
Autor: Pravin Kumar, Ine M J Segers-Nolten, Nathalie Schilderink, Vinod Subramaniam, Martina Huber
Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0142795 (2015)
Binding of human α-Synuclein, a protein associated with Parkinson's disease, to natural membranes is thought to be crucial in relation to its pathological and physiological function. Here the binding of αS to small unilamellar vesicles mimicking th
Externí odkaz: https://doaj.org/article/a8e74bee0e96432ead13645673c60bd4
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10
Lipid-Conjugated Rigidochromic Probe Discloses Membrane Alteration in Model Cells of Krabbe Disease
Autor: Giovanni Signore, Costanza Montis, Marco Cecchini, Martin Stöckl, Gerardo Abbandonato, Ilaria Tonazzini, Ranieri Bizzarri, Vinod Subramaniam, Riccardo Nifosì, Barbara Storti
Publikováno v: Biophysical journal, 116(3), 477-486. Biophysical Society
Biophysical journal (Online) 116 (2019): 477–486. doi:10.1016/j.bpj.2018.11.3141
info:cnr-pdr/source/autori:Abbandonato G.; Storti B.; Tonazzini I.; Stockl M.; Subramaniam V.; Montis C.; Nifosi R.; Cecchini M.; Signore G.; Bizzarri R./titolo:Lipid-Conjugated Rigidochromic Probe Discloses Membrane Alteration in Model Cells of Krabbe Disease/doi:10.1016%2Fj.bpj.2018.11.3141/rivista:Biophysical journal (Online)/anno:2019/pagina_da:477/pagina_a:486/intervallo_pagine:477–486/volume:116
Biophysical Journal, 116(3), 477-486. Biophysical Society
Abbandonato, G, Storti, B, Tonazzini, I, Stöckl, M, Subramaniam, V, Montis, C, Nifosì, R, Cecchini, M, Signore, G & Bizzarri, R 2019, ' Lipid-Conjugated Rigidochromic Probe Discloses Membrane Alteration in Model Cells of Krabbe Disease ', Biophysical Journal, vol. 116, no. 3, pp. 477-486 . https://doi.org/10.1016/j.bpj.2018.11.3141
The plasma membrane of cells has a complex architecture based on the bidimensional liquid-crystalline bilayer arrangement of phospho- and sphingolipids, which in turn embeds several proteins and is connected to the cytoskeleton. Several studies highl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84cf622ba94e8dec60b982226ce9d3c
https://doi.org/10.1016/j.bpj.2018.11.3141
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