Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Vinita Chauhan"'
Autor:
Christian Harry Allen, Duale Ahmed, Olivia Raiche-Tanner, Vinita Chauhan, Leila Mostaço-Guidolin, Edana Cassol, Sangeeta Murugkar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Mitochondria are the metabolic hub of the cell, playing a central role in regulating immune responses. Dysfunction of mitochondrial reprogramming can occur during bacterial and viral infections compromising hosts’ immune signaling. Compara
Externí odkaz:
https://doaj.org/article/69b38b62b31f43db85623dc9ed3fd838
Autor:
Shihori Tanabe, Jason O’Brien, Knut Erik Tollefsen, Youngjun Kim, Vinita Chauhan, Carole Yauk, Elizabeth Huliganga, Ruthann A. Rudel, Jennifer E. Kay, Jessica S. Helm, Danielle Beaton, Julija Filipovska, Iva Sovadinova, Natalia Garcia-Reyero, Angela Mally, Sarah Søs Poulsen, Nathalie Delrue, Ellen Fritsche, Karsta Luettich, Cinzia La Rocca, Hasmik Yepiskoposyan, Jördis Klose, Pernille Høgh Danielsen, Maranda Esterhuizen, Nicklas Raun Jacobsen, Ulla Vogel, Timothy W. Gant, Ian Choi, Rex FitzGerald
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are formed as a result of natural cellular processes, intracellular signaling, or as adverse responses associated with diseases or exposure to oxidizing chemical and non-chemical stres
Externí odkaz:
https://doaj.org/article/6e4603ffc4664fc2936ec3f4a2a4f907
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Adverse outcome pathways (AOPs) synthesize toxicological information to convey and weigh evidence in an accessible format. AOPs are constructed in modules that include key events (KEs) and key event relationships (KERs). This modular structure facili
Externí odkaz:
https://doaj.org/article/b569dd102627472a8059640af0095a84
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Botulinum neurotoxins (BoNTs) represent a family of bacterial toxins responsible for neuroparalytic disease ‘botulism’ in human and animals. Their potential use as biological weapon led to their classification in category ‘A’ biowarf
Externí odkaz:
https://doaj.org/article/a77fcbcca8e64d5d85a856dbbf4c6918
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 143, Iss , Pp 112134- (2021)
The efficacy of small molecule inhibitors (SMIs) against the enzymatic activity of Shiga toxin prompted the evaluation of their efficacy on related toxins viz. ricin and abrin. Ricin, like Shiga toxin, is listed as a category B bioweapon and belongs
Externí odkaz:
https://doaj.org/article/1193b5079d8743868fcd4259bf151202
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 7, Pp 1399-1405 (2006)
To obtain a panel of monoclonal antibodies (MAbs) to study the folding and conformation of the low density lipoprotein receptor (LDLr), we have generated hybridomas from LDLr-deficient mice that had been immunized with the extracellular domain of the
Externí odkaz:
https://doaj.org/article/7e144b8dcc4b4e2b86f77f0ee838df35
Autor:
Xingyu Wang, Vinita Chauhan, Anh T. Nguyen, Joshua Schultz, Jean Davignon, Stephen G. Young, Jan Borén, Thomas L. Innerarity, Hui Rutai, Ross W. Milne
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 3, Pp 547-553 (2003)
LDL from human apolipoprotein B-100 (apoB-100) transgenic (HuBTg+/+) mice contains more triglyceride than LDL from normolipidemic subjects. To obtain novel monoclonal antibody (MAb) probes of apoB conformation, we generated hybridomas from HuBTg+/+ t
Externí odkaz:
https://doaj.org/article/5d3f6d1a8e364d988d1024d5e93258e4
Autor:
Padma Singh, Manglesh Kumar Singh, Dilip Chaudhary, Vinita Chauhan, Pranay Bharadwaj, Apurva Pandey, Nisha Upadhyay, Ram Kumar Dhaked
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47110 (2012)
Botulinum neurotoxins (BoNTs), etiological agents of the life threatening neuroparalytic disease botulism, are the most toxic substances currently known. The potential for the use as bioweapon makes the development of small-molecule inhibitor against
Externí odkaz:
https://doaj.org/article/3aa7304962a043a48e0294dc4c1e006e
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
Alpha- (α-) particle radiation exposure has been linked to the development of lung cancer and has been identified as a radiation type likely to be employed in radiological dispersal devices. Currently, there exists a knowledge gap concerning cytokin
Externí odkaz:
https://doaj.org/article/0a68a412096445c1b5dccb085ffa50d8
Autor:
Vinita Chauhan, Matthew Howland
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
This study examined alpha (α-) particle radiation effects on global changes in gene expression in human leukemic monocytic cells (THP-1) for the purposes of mining for candidate biomarkers that could be used for the development of a biological asses
Externí odkaz:
https://doaj.org/article/235e9c034dea46c584248587a4b0bd97