Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Vinita, Takiar"'
Autor:
Maulee Sheth, Manju Sharma, Maria Lehn, HasanAl Reza, Takanori Takebe, Vinita Takiar, Trisha Wise-Draper, Leyla Esfandiari
Publikováno v:
APL Bioengineering, Vol 8, Iss 3, Pp 036106-036106-13 (2024)
Extracellular biophysical cues such as matrix stiffness are key stimuli tuning cell fate and affecting tumor progression in vivo. However, it remains unclear how cancer spheroids in a 3D microenvironment perceive matrix mechanical stiffness stimuli a
Externí odkaz:
https://doaj.org/article/6437b49be11f4c28824d29df5db0a4ae
Autor:
Abdallah S.R. Mohamed, Geoffrey V. Martin, Sweet Ping Ng, Vinita Takiar, Beth M. Beadle, Mark Zafereo, Adam S. Garden, Steven J. Frank, C. David Fuller, G. Brandon Gunn, William H. Morrison, David I. Rosenthal, Jay Reddy, Amy Moreno, Anna Lee, Jack Phan
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 44, Iss , Pp 100700- (2024)
Purpose/Objectives: The purpose of this study was to evaluate patterns of locoregional recurrence (LRR) after surgical salvage and adjuvant reirradiation with IMRT for recurrent head and neck squamous cell cancer (HNSCC). Materials/Methods: Patterns
Externí odkaz:
https://doaj.org/article/970eecad6bb64101b3040a2e83f493a3
Autor:
Joseph R. Peterson, John A. Cole, John R. Pfeiffer, Gregory H. Norris, Yuhan Zhang, Dorys Lopez-Ramos, Tushar Pandey, Matthew Biancalana, Hope R. Esslinger, Anuja K. Antony, Vinita Takiar
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Generalizable population-based studies are unable to account for individual tumor heterogeneity that contributes to variability in a patient’s response to physician-chosen therapy. Although molecular characterization of tumors h
Externí odkaz:
https://doaj.org/article/12eef036e02a49309bc1c05dd6fdb0b4
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionIodine-125 loaded Collaborative Ocular Melanoma Study plaques can achieve excellent tumor control for patients diagnosed with uveal melanomas. Our ocular cancer team hypothesized that use of novel, partially loaded COMS plaques could ease
Externí odkaz:
https://doaj.org/article/485c2c87811f4c25a9fdd63c89f45bcc
A phase I/II trial of concurrent immunotherapy with chemoradiation in locally advanced larynx cancer
Autor:
Andrew J. Frankart, Nooshin Hashemi Sadraei, Brad Huth, Kevin P. Redmond, William L. Barrett, Nicky Kurtzweil, Muhammad K. Riaz, Trisha Wise‐Draper, Cristina P. Rodriguez, David J. Adelstein, Vinita Takiar
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 2, Pp 437-443 (2022)
Abstract Objectives Cisplatin‐based chemoradiation is an established organ‐preserving strategy for locally advanced laryngeal cancer, but long‐term survival remains suboptimal. Immunotherapy has been studied in the metastatic and unresectable r
Externí odkaz:
https://doaj.org/article/d8499775fe624b01ae88778a9faaa52a
Autor:
John A. Bouranis, Carmen P. Wong, Laura M. Beaver, Sandra L. Uesugi, Ethan M. Papenhausen, Jaewoo Choi, Edward W. Davis, Adilson Nunes Da Silva, Newton Kalengamaliro, Rekha Chaudhary, Jordan Kharofa, Vinita Takiar, Thomas J. Herzog, William Barrett, Emily Ho
Publikováno v:
Foods, Vol 12, Iss 20, p 3784 (2023)
Cruciferous vegetable consumption is associated with numerous health benefits attributed to the phytochemical sulforaphane (SFN) that exerts antioxidant and chemopreventive properties, among other bioactive compounds. Broccoli sprouts, rich in SFN pr
Externí odkaz:
https://doaj.org/article/4c301fb6a56b4196ac2494c2b8112e29
Autor:
Maria A Lehn, Trisha M Wise-Draper, Shuchi Gulati, Vinita Takiar, Sarah Palackdharry, Mario Medvedovic, Timothy Stone, Joseph Curry, Vidhya Karivedu, McKenzie Crist, Benyamin Yaniv, Michael Borchers, Bethany Fuhrman, Audrey Crago, Ubaldo Martinez-Outschoorn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 11 (2022)
Background Metformin slows tumor growth and progression in vitro, and in combination with chemoradiotherapy, resulted in high overall survival in patients with head and neck cancer squamous cell carcinoma (HNSCC) in our phase 1 clinical trial (NCT023
Externí odkaz:
https://doaj.org/article/d5e39b30e67c484baead80341faf7c76
Autor:
Adam Luginbuhl, Alyssa Calder, David Kutler, Chad Zender, Trisha Wise-Draper, Jena Patel, Michael Cheng, Vidhya Karivedu, Tingting Zhan, Bhupesh Parashar, Shuchi Gulati, Min Yao, Pierre Lavertu, Vinita Takiar, Alice Tang, Jennifer Johnson, William Keane, Joseph Curry, David Cognetti, Voichita Bar-Ad
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
IntroductionSurgery is the primary treatment for resectable, non-metastatic recurrent head and neck squamous cell carcinoma (HNSCC). We explore the safety and oncologic benefit of intraoperative Cesium-131 (Cs-131) brachytherapy combined with salvage
Externí odkaz:
https://doaj.org/article/ba29a7da59e44f3bb050998caaaec7d4
Autor:
Amy C. Moreno, Christopher Wilke, He Wang, Shi-Ming Samuel Tung, Courtney Pollard, III, Adam S. Garden, William H. Morrison, David I. Rosenthal, Clifton D. Fuller, Gary B. Gunn, Jay P. Reddy, Shalin J. Shah, Steven J. Frank, Vinita Takiar, Jack Phan
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 10, Iss , Pp 29-34 (2019)
Background and purpose: Minimizing radiation dose exposure to nearby organs is key to limiting clinical toxicities associated with radiotherapy. Several treatment modalities such as split- or whole-field intensity-modulated radiotherapy (SF-IMRT, WF-
Externí odkaz:
https://doaj.org/article/6cd89a88e0b74532a113606f0e9c2c79
Autor:
Shuchi Gulati, McKenzie Crist, Muhammed Kashif Riaz, Vinita Takiar, Maria Lehn, Ilaina Monroe, Sarah Palackdharry, Nicky Kurtzweil, Roman Jandarov, Nusrat Harun, Trisha M. Wise-Draper
Publikováno v:
Clinical Cancer Research. 29:1906-1915
Purpose: The efficacy of cetuximab is poor in metastatic head and neck squamous cell carcinoma (HNSCC). Cetuximab initiates natural killer (NK) cell–mediated antibody-dependent cellular cytotoxicity, with resultant recruitment of immune cells and s