Výsledky vyhledávání - "Vinicius S. Londero"

Antitrypanosomal Lactones from Nectandra barbellata

Autor: Fernanda F. Camilo, Andre G. Tempone, Andrea N. L. Batista, João Henrique G. Lago, Larissa V.F. Oliveira, Vinicius S. Londero, João M. Batista, João Batista Baitello, Guilherme Medeiros Antar, Thais A. Costa-Silva

Publikováno v: Journal of Natural Products. 84:1489-1497

Twigs of Nectandra barbellata were extracted using a solution of the ionic liquid 1-butyl-3-methylimidazolium bromide (BMImBr) in H2O, assisted by microwave (MAE). After successive chromatographic steps, one sesquiterpene, costic acid, and three new

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37c35fd2c1151afac0004d612ca45be7
https://doi.org/10.1021/acs.jnatprod.0c01303

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Molecular dereplication of volatile oils from Saururus cernuus L. and evaluation of anti-Trypanosoma cruzi activity

Autor: João L. Baldim, Andre G. Tempone, Juliana Ferreira de Brito, Edgard A. Ferreira, Vinicius S. Londero, Thais A. Costa-Silva, João Henrique G. Lago

Publikováno v: Química Nova v.45 n.2 2022
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Volume: 45, Issue: 2, Pages: 159-164, Published: 22 APR 2022

The present study reports the molecular dereplication and the evaluation of anti-Trypanosoma cruzi activity of volatile oils from inflorescences, leaves, branches, and roots of Saururus cernuus L. (Saururaceae). Chemically, the oils showed the predom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b12ad8f815a69d199820be64041b50e
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000200159

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Acetylenic fatty acids from Porcelia macrocarpa (Annonaceae) against trypomastigotes of Trypanosoma cruzi: Effect of octadec-9-ynoic acid in plasma membrane electric potential

Autor: Juliana T. Mesquita, Andre G. Tempone, Kaio S. Gomes, João Henrique G. Lago, Gerold Jerz, Thais A. Costa-Silva, Maria Claudia Marx Young, Daiane D. Ferreira, Vinicius S. Londero

Publikováno v: Bioorganic Chemistry. 78:307-311

Porcelia macrocarpa (Warm.) R. E. Fries (Annonaceae) is an endemic plant in Brazil where its tasty pulp has been eaten fresh. The hexane extract from its flowers was subjected to chromatographic procedures to afford four acetylene derivatives identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9673ca22d5a1f8d74f3a830603ef1c
https://doi.org/10.1016/j.bioorg.2018.03.025

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Anti-Trypanosoma cruzi activity of costic acid isolated from Nectandra barbellata (Lauraceae) is associated with alterations in plasma membrane electric and mitochondrial membrane potentials

Autor: Andre G. Tempone, Thais A. Costa-Silva, Guilherme Medeiros Antar, Fernanda Thevenard, João Batista Baitello, Vinicius S. Londero, João Henrique G. Lago, Gislene Mitsue Namiyama

Publikováno v: Bioorganic Chemistry. 95:103510

As part of our continuous studies on prospecting metabolites from Brazilian plant species with pharmacologic activity against Trypanosoma cruzi, the n-hexane extract from twigs of Nectandra barbellata (Lauraceae) was subjected to a bioactivity-guided

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cce85e689aa06758075d49185c2506b
https://doi.org/10.1016/j.bioorg.2019.103510

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Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages

Autor: Gerold Jerz, Fernanda S. de Sousa, Vinicius S. Londero, João Henrique G. Lago, Marta L. Lima, Mariana K. Galuppo, Simone S. Grecco, Carolina Horta Andrade, Thais A. Costa-Silva, Bruno J. Neves, Andre G. Tempone

Publikováno v: Chemico-biological interactions. 277

Chagas disease is a neglected tropical disease, caused by the protozoan parasite Trypanosoma cruzi, which affects more than eight million people in Tropical and Subtropical countries especially in Latin America. Current treatment is limited to nifurt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dba249750c07b403582b47d24d905be
https://pubmed.ncbi.nlm.nih.gov/28864277

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Circadian variation and in vitro cytotoxic activity evaluation of volatile compounds from leaves of Piper regnellii (Miq) C. DC. var. regnellii (C. DC.) Yunck (Piperaceae)

Autor: Carlos R. Figueiredo, Vinicius S. Londero, Natalia Girola, Roseli R. Anderson, João Henrique G. Lago

Aiming detection of circadian variation in the chemical composition of volatiles from Piper regnellii, the leaves were collected during four different periods (8, 12, 16 and 20 h) in the same day. After extraction by hydrodistillation and GC/MS analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72050e523ee1d1b2de477bc886b8a61f

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