Repositioning of Tamoxifen in Surface-Modified Nanocapsules as a Promising Oral Treatment for Visceral Leishmaniasis

Autor: Débora Faria Silva, Levi Eduardo Soares Reis, Marina Guimarães Carvalho Machado, Douglas Daniel Dophine, Vinicius Roberto de Andrade, Wanderson Geraldo de Lima, Margareth Spangler Andrade, José Mário Carneiro Vilela, Alexandre Barbosa Reis, Gwenaelle Pound-Lana, Simone Aparecida Rezende, Vanessa Carla Furtado Mosqueira

Publikováno v: Pharmaceutics, Vol 13, Iss 7, p 1061 (2021)

Standards of care for human visceral leishmaniasis (VL) are based on drugs used parenterally, and oral treatment options are urgently needed. In the present study, a repurposing strategy was used associating tamoxifen (TMX) with polyethylene glycol-b

Externí odkaz: https://doaj.org/article/8436429fa60d49b3a83568ba377feda3

Repositioning of Tamoxifen in Surface-Modified Nanocapsules as a Promising Oral Treatment for Visceral Leishmaniasis.

Autor: Silva, Débora Faria^1,2 (AUTHOR) debora.faria@ufop.edu.br, Reis, Levi Eduardo Soares³ (AUTHOR) levieduardo@yahoo.com.br, Machado, Marina Guimarães Carvalho² (AUTHOR) gwenicioui@gmail.com, Dophine, Douglas Daniel¹ (AUTHOR) douglasdophine@gmail.com, de Andrade, Vinicius Roberto¹ (AUTHOR) vinicius.roberto@aluno.ufop.edu.br, de Lima, Wanderson Geraldo⁴ (AUTHOR) wanderson@ufop.edu.br, Andrade, Margareth Spangler⁵ (AUTHOR) margarethcasa@gmail.com, Vilela, José Mário Carneiro⁵ (AUTHOR) jvilela@fiemg.com.br, Reis, Alexandre Barbosa³ (AUTHOR) alexreis@ufop.edu.br, Pound-Lana, Gwenaelle² (AUTHOR), Rezende, Simone Aparecida¹ (AUTHOR) rezende@ufop.edu.br, Mosqueira, Vanessa Carla Furtado² (AUTHOR) mosqueira@ufop.edu.br

Publikováno v: Pharmaceutics. Jul2021, Vol. 13 Issue 7, p1061-1061. 1p.