Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Vinicius Canale"'
Autor:
Vinicius Canale, Marianne R. Spalinger, Rocio Alvarez, Anica Sayoc-Becerra, Golshid Sanati, Salomon Manz, Pritha Chatterjee, Alina N. Santos, Hillmin Lei, Sharon Jahng, Timothy Chu, Ali Shawki, Elaine Hanson, Lars Eckmann, André J. Ouellette, Declan F. McCole
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 1, Pp 39-62 (2023)
Background & Aims: Loss-of-function variants in the PTPN2 gene are associated with increased risk of inflammatory bowel disease. We recently showed that Ptpn2 is critical for intestinal epithelial cell (IEC) barrier maintenance, IEC–macrophage comm
Externí odkaz:
https://doaj.org/article/6312182efc1f47dca7056b2a59fb791d
Autor:
Marianne R. Spalinger, Vinicius Canale, Anica Becerra, Ali Shawki, Meli’sa Crawford, Alina N. Santos, Pritha Chatterjee, Jiang Li, Meera G. Nair, Declan F. McCole
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Macrophages intimately interact with intestinal epithelial cells, but the consequences of defective macrophage–epithelial cell interactions for protection against enteric pathogens are poorly understood. Here, we show that in mice with a deletion i
Externí odkaz:
https://doaj.org/article/4a7e0dcb82a94f50a7e8005e4bb6f94c
Autor:
Ali Shawki, Rocio Ramirez, Marianne R. Spalinger, Paul M. Ruegger, Anica Sayoc-Becerra, Alina N. Santos, Pritha Chatterjee, Vinicius Canale, Jonathan D. Mitchell, John C. Macbeth, Casey M. Gries, Michel L. Tremblay, Ansel Hsiao, James Borneman, Declan F. McCole
Publikováno v:
Gut Microbes, Vol 11, Iss 6, Pp 1547-1566 (2020)
Inflammatory bowel disease (IBD) pathogenesis involves significant contributions from genetic and environmental factors. Loss-of-function single-nucleotide polymorphisms (SNPs) in the protein tyrosine phosphatase non-receptor type 2 (PTPN2) gene incr
Externí odkaz:
https://doaj.org/article/20562da928e4413393bb29a2492d7c9e
Autor:
Pritha Chatterjee, Marianne Spalinger, Ali Shawki, Alina Santos, Anica Sayoc, Hillmin Lei, Saloman Manz, Meli'sa Crawford, Vinicius Canale, James Borneman, Declan McCole
Publikováno v:
Physiology. 38
Background: Alterations in epithelial tight junction proteins can compromise the ability of the intestinal mucosa to act as a barrier between luminal contents and underlying tissues. The resulting increase in intestinal permeability can give rise to
Autor:
Vinicius Canale, Declan McCole
Publikováno v:
Physiology. 38
Loss-of-function variants in the Protein Tyrosine Phosphatase non-receptor Type 2 ( PTPN2) gene are associated with increased risk of Inflammatory Bowel Disease (IBD). PTPN2 encodes T Cell Protein Tyrosine Phosphatase (TCPTP), a negative regulator of
Autor:
Hillmin Lei, Ali Shawki, Marianne Spalinger, Vinicius Canale, Alina Santos, Pritha Chatterjee, Meli’sa Crawford, Salomon Manz, Michael Scharl, Declan McCole
Publikováno v:
Physiology. 38
Background: Anemia is the most frequent extraintestinal manifestation of inflammatory bowel disease (IBD) and is associated with the risk of Crohn’s disease. Anemia significantly impairs quality of life, increases hospitalization rates, and increas
Autor:
Vinicius Canale, Declan McCole
Publikováno v:
Physiology. 38
Loss-of-function variants in the Protein Tyrosine Phosphatase non-receptor Type 2 ( PTPN2) gene are associated with increased risk of Inflammatory Bowel Disease (IBD). PTPN2 encodes T Cell Protein Tyrosine Phosphatase (TCPTP), a negative regulator of
Autor:
Hillmin Lei, Ali Shawki, Marianne R. Spalinger, Vinicius Canale, Alina N. Santos, Pritha Chatterjee, Meli’sa S. Crawford, Salomon Manz, Anica Becerra, Michael Scharl, Declan F. McCole
Publikováno v:
The FASEB Journal. 36
Autor:
James Borneman, Marianne R. Spalinger, Jonathan D. Mitchell, Declan F. McCole, Pritha Chatterjee, Ansel Hsiao, Vinicius Canale, John C. Macbeth, Alina N. Santos, Casey M. Gries, Anica Sayoc, Ali Shawki, Rocio Ramirez, Michel L. Tremblay, Paul M. Ruegger
Publikováno v:
Gut Microbes, Vol 11, Iss 6, Pp 1547-1566 (2020)
Gut microbes, vol 11, iss 6
Gut microbes, vol 11, iss 6
Inflammatory bowel disease (IBD) pathogenesis involves significant contributions from genetic and environmental factors. Loss-of-function single-nucleotide polymorphisms (SNPs) in the protein tyrosine phosphatase non-receptor type 2 (PTPN2) gene incr
Autor:
Ali Shawki, Anica Sayoc-Becerra, Michel L. Tremblay, Alina N. Santos, James Borneman, Declan F. McCole, Michael Scharl, Marianne R. Spalinger, Pritha Chatterjee, Vinicius Canale
Publikováno v:
Gut, vol 71, iss 1
Gut
Gut
ObjectivesAlterations in the intestinal microbiota are linked with a wide range of autoimmune and inflammatory conditions, including inflammatory bowel diseases (IBD), where pathobionts penetrate the intestinal barrier and promote inflammatory reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61430991c7322252dc2500e571c16e5b