Výsledky vyhledávání - "Vinicio T.S. Coelho"

Digitoxigenin presents an effective and selective antileishmanial action against Leishmania infantum and is a potential therapeutic agent for visceral leishmaniasis

Publikováno v: Parasitology Research

Treatment for visceral leishmaniasis (VL) is hampered mainly by drug toxicity, their high cost, and parasite resistance. Drug development is a long and pricey process, and therefore, drug repositioning may be an alternative worth pursuing. Cardenolid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0427928eb7a91299782d1e74eab081
https://doi.org/10.1007/s00436-020-06971-2

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Evaluation of the in vitro and in vivo antileishmanial activity of a chloroquinolin derivative against Leishmania species capable of causing tegumentary and visceral leishmaniasis

Autor: Elaine Soares Coimbra, Vinicio T.S. Coelho, Patrícia A.F. Ribeiro, Guilherme R. Pereira, Guilherme Firmo De Matos, Luísa Perin, Pedro Henrique De Almeida Simões Neves, Eduardo A.F. Coelho, Grasiele S.V. Tavares, Andreza Cristina Gomes Ferreira, Daniel Dias, Débora V.C. Mendonça, Fernanda Ludolf, Daniela P. Lage, Luciana M.R. Antinarelli, Tauane G. Soyer, Miguel A. Chávez-Fumagalli

Publikováno v: Experimental Parasitology. 199:30-37

The treatment against leishmaniasis presents problems, since the currently used drugs are toxic and/or have high costs. In addition, parasite resistance has increased. As a consequence, in this study, a chloroquinolin derivative, namely 7-chloro-N,N-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd00ae1668a2bd906ceb49f8607fde76
https://doi.org/10.1016/j.exppara.2019.02.019

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In silico Leishmania proteome mining applied to identify drug target potential to be used to treat against visceral and tegumentary leishmaniasis

Autor: Eduardo A.F. Coelho, Daniel Dias, Débora V.C. Mendonça, Lourena E. Costa, Daniela P. Lage, Miguel A. Chávez-Fumagalli, Vinicio T.S. Coelho, Grasiele S.V. Tavares, Patrícia A.F. Ribeiro, Fernanda Ludolf

Publikováno v: Journal of Molecular Graphics and Modelling. 87:89-97

New therapeutic strategies against leishmaniasis are desirable, since the treatment against disease presents problems, such as the toxicity, high cost and/or parasite resistance. As consequence, new antileishmanial compounds are necessary to be ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d18a185e70dae3e8a4d2b7eb1a8e51
https://doi.org/10.1016/j.jmgm.2018.11.014

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A chloroquinoline derivate presents effective in vitro and in vivo antileishmanial activity against Leishmania species that cause tegumentary and visceral leishmaniasis

Autor: Luciana M.R. Antinarelli, Luísa Perin, Grasiele S.V. Tavares, Daniela P. Lage, Elaine Soares Coimbra, João A. Oliveira-da-Silva, Denis F. Alvarenga, Patrícia A.F. Ribeiro, Geraldo Célio Brandão, Jessica K.T. Sousa, Fernanda Ludolf, Eduardo A.F. Coelho, Bianka A. Oliveira, Vinicio T.S. Coelho, Guilherme R. Pereira, Miguel A. Chávez-Fumagalli, Vandack Nobre, Daniel Dias, Débora V.C. Mendonça

Publikováno v: Parasitology international. 73

The identification of new therapeutics to treat leishmaniasis is desirable, since available drugs are toxic and present high cost and/or poor availability. Therefore, the discovery of safer, more effective and selective pharmaceutical options is of u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013d93b575235d887428c6db0b2dce50
https://pubmed.ncbi.nlm.nih.gov/31362122

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α-Galactosidases production by Debaryomyces hansenii UFV-1

Autor: Vinicio T.S. Coelho, Solimar Gonçalves Machado, Pollyanna Amaral Viana, Gabriela Picollo Maitan, Flávia M. L. Passos, Sebastião Tavares de Rezende, Valéria Monteze Guimarães

Publikováno v: LOCUS Repositório Institucional da UFV
Universidade Federal de Viçosa (UFV)
instacron:UFV

Extracellular and intracellular α-galactosidases were produced by yeast Debaryomyces hansenii UFV-1 grown on different media with several carbon sources. D. hansenii grown in YP-medium (1% yeast extract and 2% peptone) presented maximum cell mass (8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb2fb5227d2774e929e7381fce44609
https://doi.org/10.1007/s10068-011-0085-7

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Specific Serodiagnosis of Canine Visceral Leishmaniasis Using Leishmania Species Ribosomal Protein Extracts▿

Autor: Laura Ramírez, Vinicio T.S. Coelho, C.G. Nieto, Manuel Soto, Eduardo A.F. Coelho, Daniel R. Abánades, Pedro Bonay, Mariana Amalia Figueiredo Costa, Miguel A. Chávez-Fumagalli, Vívian T. Martins, Dulcilene Mayrink de Oliveira, Carlos Alonso, Carlos Alberto Pereira Tavares

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

In the present work, we have analyzed the antigenicity of Leishmania species ribosomal proteins (LRPs). To accomplish this, Leishmania infantum ribosomes were biochemically purified from promastigote cytosolic extracts, and their reactivities were an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae120541ffeefeab5f91ee5ab71679e2
https://europepmc.org/articles/PMC2786384/

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Identification of Proteins in Promastigote and Amastigote-like Leishmania Using an Immunoproteomic Approach

Autor: Paula S. Lage, Ana Paula Fernandes, Jamil S. Oliveira, Vinicio T.S. Coelho, Miguel A. Chávez-Fumagalli, Diogo G. Valadares, Manuel Soto, Eduardo A.F. Coelho, Mariana C. Duarte, Carlos Alberto Pereira Tavares, Marcelo M. Santoro

Publikováno v: PLoS Neglected Tropical Diseases, Vol 6, Iss 1, p e1430 (2012)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Neglected Tropical Diseases

Background: The present study aims to identify antigens in protein extracts of promastigote and amastigote-like Leishmania (Leishmania) chagasi syn. L. (L.) infantum recognized by antibodies present in the sera of dogs with asymptomatic and symptomat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45388c7e4f8a364b6bc927dd30a9190f
https://doi.org/10.1371/journal.pntd.0001430

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