Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vinicia Assunta Polito"'
Autor:
Marika Guercio, Simona Manni, Iolanda Boffa, Simona Caruso, Stefano Di Cecca, Matilde Sinibaldi, Zeinab Abbaszadeh, Antonio Camera, Roselia Ciccone, Vinicia Assunta Polito, Francesca Ferrandino, Sofia Reddel, Maria Luigia Catanoso, Emilia Bocceri, Francesca Del Bufalo, Mattia Algeri, Biagio De Angelis, Concetta Quintarelli, Franco Locatelli
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T cells engineered with chimeric antigen receptor (CAR-T cells) are an effective treatment in patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia or B-cell non-Hodgkin lymphoma. Despite the reported exciting clinical resul
Externí odkaz:
https://doaj.org/article/22257a3336434483b101ea658433576b
Autor:
Malcolm K Brenner, Valentina Hoyos, Ignazio Caruana, Gerrit Weber, Claudia Manuela Arnone, Vinicia Assunta Polito, Angela Mastronuzzi, Andrea Carai, Francesca Camassei Diomedi, Laura Antonucci, Maria Vinci, Francesco Ferrari, Elisa Salviato, Marco Scarsella, Cristiano De Stefanis, Lucia Lisa Petrilli
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Pediatric high-grade gliomas (pHGGs) are among the most common and incurable malignant neoplasms of childhood. Despite aggressive, multimodal treatment, the outcome of children with high-grade gliomas has not significantly improved over th
Externí odkaz:
https://doaj.org/article/92dca105104a4c0ab4b5ec8234f913f1
Autor:
Concetta Quintarelli, Domenico Orlando, Iolanda Boffa, Marika Guercio, Vinicia Assunta Polito, Andrea Petretto, Chiara Lavarello, Matilde Sinibaldi, Gerrit Weber, Francesca Del Bufalo, Ezio Giorda, Marco Scarsella, Stefania Petrini, Daria Pagliara, Franco Locatelli, Biagio De Angelis, Ignazio Caruana
Publikováno v:
OncoImmunology, Vol 7, Iss 6 (2018)
Chimeric antigen receptor (CAR) T-cell therapy has been shown to be dramatically effective in the treatment of B-cell malignancies. However, there are still substantial obstacles to overcome, before similar responses can be achieved in patients with
Externí odkaz:
https://doaj.org/article/fabff666ba614e11a49e9498c35f82a8
Autor:
Claudia Manuela Arnone, Stephen Gottschalk, Vinicia Assunta Polito, Lucia Lisa Petrilli, Francesco Ferrari, Maria Vinci, Concetta Quintarelli, Biagio De Angelis, Laura Antonucci, Francesca Camassei Diomedi, Elisa Salviato, Gerrit Weber, Valentina Hoyos, Franco Locatelli, Angela Mastronuzzi, Ignazio Caruana, Marco Scarsella, Francesca Del Bufalo, Andrea Carai, Malcolm K. Brenner, Cristiano De Stefanis
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
BackgroundPediatric high-grade gliomas (pHGGs) are among the most common and incurable malignant neoplasms of childhood. Despite aggressive, multimodal treatment, the outcome of children with high-grade gliomas has not significantly improved over the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c9f05090651a45a461ea3ba836bf15
https://hdl.handle.net/10807/228541
https://hdl.handle.net/10807/228541
Autor:
Angela Pitisci, Rosaria Cristantielli, Andrea Petretto, Franco Locatelli, Ignazio Caruana, Tamascia Belardinilli, Francesca Del Bufalo, Claudia Manuela Arnone, Vinicia Assunta Polito, Nicola Tumino, Ezio Giorda, Concetta Quintarelli, Biagio De Angelis, Laura Antonucci, Gerrit Weber
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
In the last years, important progresses have been registered in the treatment of patients suffering from oncological/haematological malignancies, but more still needs to be done to reduce toxicity and side effects, improve outcome and offer new strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1974c1fa59c4190a326dcbb03af664f7
https://www.frontiersin.org/article/10.3389/fimmu.2019.02717/full
https://www.frontiersin.org/article/10.3389/fimmu.2019.02717/full
Autor:
Antonella Cacchione, Tamascia Belardinilli, Evelina Miele, Franco Locatelli, Biagio De Angelis, Claudia Manuela Arnone, Francesca Diomedi Camassei, Andrea Carai, Angela Mastronuzzi, Ignazio Caruana, Concetta Quintarelli, Francesca Del Bufalo, Giulia Ceglie, Cristiano De Stefanis, Vinicia Assunta Polito
Solid tumours are characterized by a high structural complexity that is difficult to reproduce with common bidimensional (2D) systems. We developed an innovative fibrin-based hydrogel 3D model and tested it as platform to establish primary LGG cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fd7bb7bc9c02f5ab062faf9f878614
https://europepmc.org/articles/PMC6477242/
https://europepmc.org/articles/PMC6477242/
Autor:
Luciana Vinti, Domenico Orlando, S. De Cecca, Maria Giuseppina Cefalo, Matilde Sinibaldi, Francesco Locatelli, Vinicia Assunta Polito, Marika Guercio, Rosaria Cristantielli, Iolanda Boffa, Pietro Merli, F. Del Bufalo, Ignazio Caruana, Concetta Quintarelli, Mattia Algeri, B. De Angelis, Zeinab Abbaszadeh, G Li Pira, Valentina Bertaina
Publikováno v:
HemaSphere. 3:755
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db7ef1012403aa3ee28e942b918c4874
https://doi.org/10.1097/01.hs9.0000564788.37982.52
https://doi.org/10.1097/01.hs9.0000564788.37982.52
Autor:
Rosaria Salvia, Vinicia Assunta Polito, Edoardo Nusco, Roman S. Polishchuk, Serena Abbondante, Maria Pia Cosma
Publikováno v:
Human Molecular Genetics
Mucopolysaccharidosis type II (MPSII), or Hunter syndrome, is a devastating disorder associated with a shortened life expectancy. Patients affected by MPSII have a variety of symptoms that affect all organs of the body and may include progressive cog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fa59a1b1f6e026551886f76c3f9be2
https://doi.org/10.1093/hmg/ddq420
https://doi.org/10.1093/hmg/ddq420
Autor:
Silvia Galardi, Vinicia Assunta Polito, Franco Locatelli, Shahar Alon, Eli Eisenberg, Susanna Raho, Carlo Presutti, Angela Gallo, Federica Galeano, Sara Vincenti, Sara Tomaselli
Publikováno v:
Genome Biology
Background ADAR enzymes convert adenosines to inosines within double-stranded RNAs, including microRNA (miRNA) precursors, with important consequences on miRNA retargeting and expression. ADAR2 activity is impaired in glioblastoma and its rescue has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5dafcb1d8c8a07d664a4769ac57b6f6
https://hdl.handle.net/10807/229987
https://hdl.handle.net/10807/229987
Autor:
Andrea Ballabio, Vinicia Assunta Polito, Linda Mann, Alberto Auricchio, Stefano Pepe, Alessandra d'Azzo, Maria Pia Cosma, Monica Cardone
Publikováno v:
Human Molecular Genetics. 15:1225-1236
Mucopolysaccharidosis type II (MPSII; Hunter syndrome) is a lysosomal storage disorder caused by a deficiency in the enzyme iduronate 2-sulfatase (IDS). At present, the therapeutic approaches for MPSII are enzyme replacement therapy and bone marrow t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7affdd1d67743b41a245102519f94f80
https://doi.org/10.1093/hmg/ddl038
https://doi.org/10.1093/hmg/ddl038