Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Vini John"'
Autor:
Ellen Merrick Schill, Elisabeth L. Joyce, Alexandria N. Floyd, Sreeram Udayan, Brigida Rusconi, Shreya Gaddipati, Bibiana E. Barrios, Vini John, Mitchell E. Kaye, Devesha H. Kulkarni, Jocelyn T. Pauta, Keely G. McDonald, Rodney D. Newberry
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Vancomycin is a broad-spectrum antibiotic widely used in cases of suspected sepsis in premature neonates. While appropriate and potentially lifesaving in this setting, early-life antibiotic exposure alters the developing microbiome and is associated
Externí odkaz:
https://doaj.org/article/bccd6db9f3e6464fbc0f906da2b01059
Autor:
Leigh A. Kotzé, Carly Young, Vinzeigh N. Leukes, Vini John, Zhuo Fang, Gerhard Walzl, Manfred B. Lutz, Nelita du Plessis
Publikováno v:
EBioMedicine, Vol 53, Iss , Pp - (2020)
Mycobacterium tuberculosis (M.tb) is likely the most successful human pathogen, capable of evading protective host immune responses and driving metabolic changes to support its own survival and growth. Ineffective innate and adaptive immune responses
Externí odkaz:
https://doaj.org/article/1a0e3d9e8311438990e96e6f9a8af54f
Autor:
Vini John, Leigh A. Kotze, Eliana Ribechini, Gerhard Walzl, Nelita Du Plessis, Manfred B. Lutz
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Monocytic myeloid-derived suppressor cells (M-MDSCs) and granulocytic MDSCs (G-MDSCs) have been found to be massively induced in TB patients as well in murine Mtb infection models. However, the interaction of mycobacteria with MDSCs and its role in T
Externí odkaz:
https://doaj.org/article/8f58f45c06bf42298ba25fe69fdd05f6
Publikováno v:
Biology Open, Vol 7, Iss 6 (2018)
BCG (Bacillus Calmette-Guérin) is the only available vaccine against TB and is also used for the treatment of superficial bladder cancer. BCG-mediated protection against TB and bladder cancer has been shown to rely on its ability to induce superior
Externí odkaz:
https://doaj.org/article/3ca31194706a4ad8ab089633a397988a
Autor:
Cinthia Silva-Vilches, Katrien Pletinckx, Miriam Lohnert, Vladimir Pavlovic, Diyaaeldin Ashour, Vini John, Emilia Vendelova, Susanne Kneitz, Jie Zhou, Rena Chen, Thomas Reinheckel, Thomas D Mueller, Jochen Bodem, Manfred B Lutz
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0178114 (2017)
Immature or semi-mature dendritic cells (DCs) represent tolerogenic maturation stages that can convert naive T cells into Foxp3+ induced regulatory T cells (iTreg). Here we found that murine bone marrow-derived DCs (BM-DCs) treated with cholera toxin
Externí odkaz:
https://doaj.org/article/0f72e8f87d374b4dafd39a13e4ca21fe
Autor:
Vini John, Bibiana Barrios, Sreeram Udayan, Alexandria Floyd, Ellen M Schill, Keely G McDonald, Richard S Blumberg, Rodney D Newberry
Publikováno v:
The Journal of Immunology. 208:115.06-115.06
Invariant natural killer T (iNKT) cells are innate-like T cells that secrete a wide array of cytokines and immune mediators. These cells recognize self or microbial ligands presented by cells expressing CD1d, and can contribute to host protection or/
Autor:
Keely G. McDonald, Misty Good, Jenny K. Gustafsson, Brigida Rusconi, Simon P. Hogan, Paige E. Coughlin, Charles O. Elson, I. Malick Ndao, Devesha H. Kulkarni, Chyi Song Hsieh, Vini John, Barbara B. Warner, Phillip I. Tarr, Rodney D. Newberry, Avraham Beigelman, Kathryn A. Knoop
Publikováno v:
JCI Insight
Allergic disorders, characterized by Th2 immune responses to environmental substances, are increasingly common in children in Western societies. Multiple studies indicate that breastfeeding, early complementary introduction of food allergens, and ant
Autor:
Gerhard Walzl, Manfred B. Lutz, Vinzeigh N. Leukes, Leigh A. Kotze, Vini John, Zhuo Fang, Carly Young, Nelita du Plessis
Publikováno v:
EBioMedicine
EBioMedicine, Vol 53, Iss, Pp-(2020)
EBioMedicine, Vol 53, Iss, Pp-(2020)
Mycobacterium tuberculosis (M.tb) is likely the most successful human pathogen, capable of evading protective host immune responses and driving metabolic changes to support its own survival and growth. Ineffective innate and adaptive immune responses
Publikováno v:
Biology Open, Vol 7, Iss 6 (2018)
Biology Open
Biology Open
BCG (Bacillus Calmette-Guérin) is the only available vaccine against TB and is also used for the treatment of superficial bladder cancer. BCG-mediated protection against TB and bladder cancer has been shown to rely on its ability to induce superior
Publikováno v:
Journal of Leukocyte Biology. 97:511-520
MIP is a nonpathogenic, soil-borne predecessor of Mycobacterium avium. It has been reported previously that MIP possesses strong immunomodulatory properties and confers protection against experimental TB and tumor. DCs, by virtue of their unmatched a