Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vineshkumar Thidil Puliyappadamba"'
Autor:
Vineshkumar Thidil Puliyappadamba, Sharmistha Chakraborty, Sandili S. Chauncey, Li Li, Kimmo J. Hatanpaa, Bruce Mickey, Shayan Noorani, Hui-Kuo G. Shu, Sandeep Burma, David A. Boothman, Amyn A. Habib
Publikováno v:
Cell Reports, Vol 4, Iss 4, Pp 764-775 (2013)
RIP1 is a central mediator of cell death in response to cell stress but can also mediate cell survival by activating NF-κB. Here, we show that RIP1 acts as a switch in EGFR signaling. EGFRvIII is an oncogenic mutant that does not bind ligand and is
Externí odkaz:
https://doaj.org/article/1e0740c4346e492cb3607f550ed086ab
Autor:
Sharmistha Chakraborty, Li Li, Hao Tang, Yang Xie, Vineshkumar Thidil Puliyappadamba, Jack Raisanen, Sandeep Burma, David A Boothman, Brent Cochran, Julian Wu, Amyn A Habib
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 8, Pp 888-897 (2013)
Tumor necrosis factor receptor 1 (TNFR1)-associated death domain protein (TRADD) is an important adaptor in TNFR1 signaling and has an essential role in nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) activation and survival s
Externí odkaz:
https://doaj.org/article/15629bd9197a4959bdd149f8be39d34e
Autor:
Bruce E. Mickey, Jann N. Sarkaria, Dawen Zhao, Nishah Panchani, Edward Pan, Sandeep Burma, Amyn A. Habib, Toral R. Patel, Ke Gong, Sabrina Bharia, Gao Guo, Kimmo J. Hatanpaa, Bipasha Mukherjee, Ziba Damanwalla, Vineshkumar Thidil Puliyappadamba, David E. Gerber
Publikováno v:
Neuro Oncol
Background Glioblastoma (GBM) is the most common primary malignant adult brain tumor. Temozolomide (TMZ) is the standard of care and is most effective in GBMs that lack the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT). Moreover, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2d3ed85aeec967980d214f3d495281
https://pubmed.ncbi.nlm.nih.gov/31628474
https://pubmed.ncbi.nlm.nih.gov/31628474
Autor:
Vineshkumar Thidil Puliyappadamba, Sankar Sundaram, Ruby John Anto, Shabna Anwar, Vinod Vijayakurup, Arun Kumar T. Thulasidasan, Smitha V. Bava, Jayesh Antony
Publikováno v:
BioFactors. 41:431-442
Benzo[a]pyrene is a procarcinogen present in environment and cigarette smoke, which could be bio-transformed in vivo to B[a]PDE, a potent carcinogen known to form DNA adducts and induce mutations. We observed that curcumin, a known chemopreventive, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::193806c76e454a2bbf7a9ad7d7957515
https://doi.org/10.1002/biof.1244
https://doi.org/10.1002/biof.1244
Autor:
Sandeep Burma, Daisha J. Cipher, Jack M Raisanen, Ameena J. Jiwani, Amyn A. Habib, Kimmo J. Hatanpaa, Sharmistha Chakraborty, Zhixiang Wang, Alizeh Rehman, Chin-Rang Yang, Bruce E. Mickey, David A. Boothman, Debabrata Saha, Li Li, Sandeep C. Pingle, Vineshkumar Thidil Puliyappadamba, Santosh Kesari, Christopher J. Madden
Publikováno v:
Oncogene. 33:4253-4264
EGFRvIII is a key oncogene in glioblastoma (GBM). EGFRvIII results from an in-frame deletion in the extracellular domain of EGFR, does not bind ligand and is thought to be constitutively active. Although EGFRvIII dimerization is known to activate EGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1061809580edd73711e2d39455b61cf
https://doi.org/10.1038/onc.2013.400
https://doi.org/10.1038/onc.2013.400
Autor:
Edi Levi, Robert Kilkuskie, Fred R. Miller, Liyue Zhang, Scott D. Larsen, Arun K. Rishi, Anil Wali, Wenjuan Wu, Debra J. Bevis, Lisa Polin, Vineshkumar Thidil Puliyappadamba, Russell L. Finley
Publikováno v:
Journal of Biological Chemistry. 286:38000-38017
CARP-1/CCAR1, a perinuclear phosphoprotein, is a regulator of cell growth and apoptosis signaling. Although CARP-1 is a regulator of chemotherapy-dependent apoptosis, it is also a part of the NF-κB proteome and a co-activator of steroid/thyroid nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0019edb06d59be9a43e68f17010679
https://doi.org/10.1074/jbc.m111.222398
https://doi.org/10.1074/jbc.m111.222398
Autor:
Santhosh D. Ravichandran, Nikhil Ponnoor Anto, Arun Kumar T. Thulasidasan, Smitha V. Bava, Vino T. Cheriyan, Ruby John Anto, Chanickal N. Sreekanth, Sajna G. Menon, Vineshkumar Thidil Puliyappadamba
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 43:331-341
Paclitaxel is the most promising chemotherapeutic agent of plant origin despite its high cost and dose-limiting toxicity. Our earlier report has shown that cervical cancer cells can be sensitized by curcumin to paclitaxel-induced apoptosis through do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aeb8b31dad60b2b3ce1ab3853d4bc88
https://doi.org/10.1016/j.biocel.2010.09.011
https://doi.org/10.1016/j.biocel.2010.09.011
Autor:
Bipasha Mukherjee, Varun Sadaphal, Eliot Fletcher, Monica Lou, Vineshkumar Thidil Puliyappadamba, Ram Shankar Mani, Sandeep Burma, Xiang Li
Publikováno v:
Neuro-Oncology. 20:vi224-vi224
Glioblastomas (GBM) are lethal brain tumors for which surgical resection, treatment with ionizing radiation (IR) and concurrent administration of Temozolomide (TMZ) is the mainstay of therapy. These tumors are extremely radioresistant, and resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f337a7fde24e92fd476023748d3bac
https://doi.org/10.1093/neuonc/noy148.927
https://doi.org/10.1093/neuonc/noy148.927
Autor:
Sunita Sharma, Q. Ping Dou, Adi L. Tarca, John C. Ruckdeschel, Huanjie Yang, Ying Wang, Arun K. Rishi, Fulvio Lonardo, Vineshkumar Thidil Puliyappadamba, Anil Wali, Harvey I. Pass
Publikováno v:
Cancer Chemotherapy and Pharmacology. 66:455-466
Thoracic malignancies and human breast cancer (HBC) continue to be aggressive solid tumors that are poor responders to the existing conventional standard chemotherapeutic approaches. Malignant pleural mesothelioma (MPM) is an asbestos-related tumor o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc21bdab2d08194f790a14a3a5ce7426
https://doi.org/10.1007/s00280-009-1181-8
https://doi.org/10.1007/s00280-009-1181-8
Publikováno v:
Molecular & Cellular Oncology
Activation of NF-κB affects multiple aspects of cancer biology including cell survival and resistance to treatment. Glioblastoma (GBM) is the most common primary malignant tumor of the brain in adults and is resistant to treatment. Recent studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f375341da3983f1433ac4d35d6bf081
http://europepmc.org/articles/PMC4905061
http://europepmc.org/articles/PMC4905061