Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Vineetha Koroth Edavana"'
Autor:
Rosalind B. Penney, Aiwei Yao-Borengasser, Martha L. Slattery, Roger K. Wolff, Vineetha Koroth Edavana, Ishwori Dhakal, Abbie Lundgreen, Suzanne Williams, Susan Kadlubar
Publikováno v:
Pharmacogenomics and Personalized Medicine
Rosalind B Penney,1 Abbie Lundgreen,2 Aiwei Yao-Borengasser,3 Vineetha K Edavana,3 Suzanne Williams,3 Ishwori Dhakal,4 Roger K Wolff,2 Susan Kadlubar,3 Martha L Slattery2 1Department of Environmental and Occupational Health, University of Arkansas fo
Autor:
Anna Radominska-Pandya, Aleksandra K. Greer, Ishwori Dhakal, Centdrika R. Dates, Vineetha Koroth Edavana, Athena Starlard-Davenport, Moshe Finel, Stacie M. Bratton, Susan Kadlubar
Publikováno v:
Drug Metabolism and Disposition. 42:1392-1400
Tamoxifen (Tam) is a selective estrogen receptor modulator used to inhibit breast tumor growth. Tam can be directly N-glucuronidated via the tertiary amine group or O-glucuronidated after cytochrome P450–mediated hydroxylation. In this study, the g
Autor:
Aiwei Yao-Borengasser, Vineetha Koroth Edavana, Ishwori Dhakal, Gunnar Boysen, Susan Kadlubar, Suzanne Williams, Rosalind B. Penney
Publikováno v:
Drug Metabolism and Disposition. 41:870-877
Anastrozole belongs to the nonsteroidal triazole-derivative group of aromatase inhibitors. Recently, clinical trials demonstrated improved antitumoral efficacy and a favorable toxicity with third-generation aromatase inhibitors, compared with tamoxif
Autor:
Vineetha Koroth Edavana, Ishwori Dhakal, Suzanne Williams, Marjorie L. Beggs, Baitang Ning, Xinfeng Yu, Xuemei Zhang, Fred F. Kadlubar, Nicholas P. Lang, Susan Kadlubar, Kelly E. Mercer
Publikováno v:
Toxicological Sciences. 118:391-403
Sulfotransferase isoform 1A1 (SULT1A1) is the most highly expressed hepatic sulfotransferase and is involved in the biotransformation of a wide variety of endo- and xenobiotics. A common single nucleotide polymorphism (SNP) in the coding region of SU
Autor:
Alan D. Elbein, J. D. Carroll, Naoki Asano, Vineetha Koroth Edavana, Y. T. Pan, Irena Pastuszak
Publikováno v:
FEBS Journal. 275:3408-3420
Trehalose (α,α-1,1-glucosyl-glucose) is essential for the growth of mycobacteria, and these organisms have three different pathways that can produce trehalose. One pathway involves the enzyme described in the present study, trehalose synthase (TreS
Publikováno v:
FEBS Journal. 274:1701-1714
Trehalose is a nonreducing disaccharide of glucose (α,α-1,1-glucosyl-glucose) that is essential for growth and survival of mycobacteria. These organisms have three different biosynthetic pathways to produce trehalose, and mutants devoid of all thre
Autor:
Athena Starlard-Davenport, Aiwei Yao-Borengasser, Susan Kadlubar, Rosalind B. Penney, Vineetha Koroth Edavana, Ishwori Dhakal
Publikováno v:
International Journal of Cancer Research and Molecular Mechanisms ( ISSN 2381-3318 ). 1
Anastrozole is an aromatase inhibitor (AI) used as adjuvant therapy for breast cancer. Anastrozole is subject to direct glucuronidation catalyzed by UDP-glucuronosyltransferase1A4 (UGT1A4). Interindividual variability in anastrozole glucuronidation m
Autor:
Yuan T. Pan, J. David Carroll, Alan D. Elbein, William J. Jourdian, Irena Pastuszak, Vineetha Koroth Edavana, Rick Edmondson
Publikováno v:
European Journal of Biochemistry. 271:4259-4269
Trehalose synthase (TreS) catalyzes the reversible interconversion of trehalose (glucosyl-alpha,alpha-1,1-glucose) and maltose (glucosyl-alpha1-4-glucose). TreS was purified from the cytosol of Mycobacterium smegmatis to give a single protein band on
Autor:
Vineetha Koroth Edavana, Alan D. Elbein, Prajitha Thampi, Edathera C. Abraham, Irena Pastuszak, J. D. Carroll
Publikováno v:
Archives of Biochemistry and Biophysics. 426:250-257
Two open reading frames in the Mycobacterium tuberculosis genome, Rv3372 and Rv2006 , have about 25% sequence identity at the amino acid level to the trehalose-phosphate phosphatase (TPP) purified from Mycobacterium smegmatis. However, the protein pr
Autor:
Stacie M. Bratton, Susan Kadlubar, Anna Radominska-Pandya, Centdrika R. Dates, Vineetha Koroth Edavana, Aleksandra K. Greer
Publikováno v:
The FASEB Journal. 28
Tamoxifen (Tam) is a selective estrogen receptor (ER) modulator used to inhibit breast tumor growth. Tam can be directly N-glucuronidated via the tertiary amine group or O-glucuronidated after cytochrome P450 mediated hydroxylation. In this study, th