Heme- and iron-activated macrophages in sickle cell disease: an updated perspective.

Autor: Navaneethabalakrishnan S; Iron Research Laboratory, Lindsley Kimball Research Institute, New York Blood Center., An X; Laboratory of Membrane Biology, Lindsley Kimball Research Institute, New York Blood Center., Vinchi F; Iron Research Laboratory, Lindsley Kimball Research Institute, New York Blood Center.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA.

Publikováno v: Current opinion in hematology [Curr Opin Hematol] 2024 Nov 01; Vol. 31 (6), pp. 275-284. Date of Electronic Publication: 2024 Jul 16.

Iron biology.

Autor: Del Vecchio L; Department of Nephrology and Dialysis, Sant'Anna Hospital, ASST Lariana, Como 22100, Italy., Girelli D; Department of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy., Vinchi F; Iron Research Laboratory, Lindsley Kimball Research Institute, New York Blood Center, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Cozzolino M; Renal Division, Department of Health Sciences, ASST Santi Paolo e Carlo, University of Milan, Milan, Italy., Elliott S; Elliott Consulting, Thousand Oaks, CA, USA., Mark PB; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK., Valenti L; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.; Precision Medicine, Biological Resource Center Unit, Department of Transfusion Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Qian C; School of Biomedical Sciences and Gerald Choa Neuroscience Centre, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong., Guo Q; School of Medicine, Shanghai University, Shanghai, China., Qian ZM; Institute of Translational & Precision Medicine, Nantong University, Nantong, JS, China.; Laboratory of Neuropharmacology, Fudan University School of Pharmacy, Shanghai; and National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China., Ciceri P; Renal Division, Department of Health Sciences, ASST Santi Paolo e Carlo, University of Milan, Milan, Italy., Locatelli F; Department of Nephrology and Dialysis, (Past Director) Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy.

Publikováno v: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2024 Aug 30; Vol. 39 (9), pp. 1404-1415.

News on sickle cell disease: Heme-driven disordered erythropoiesis.

Autor: Vinchi F; Iron Research Laboratory, Lindsley Kimball Research Institute New York Blood Center New York New York USA.; Department of Pathology and Laboratory Medicine Weill Cornell Medicine New York New York USA.

Publikováno v: HemaSphere [Hemasphere] 2024 May 17; Vol. 8 (5), pp. e75. Date of Electronic Publication: 2024 May 17 (Print Publication: 2024).

Hemolysis-driven IFNα production impairs erythropoiesis by negatively regulating EPO signaling in sickle cell disease.

Autor: Han Y; Laboratory of Membrane Biology, New York Blood Center, New York, NY., Gao C; Laboratory of Membrane Biology, New York Blood Center, New York, NY., Liu Y; Laboratory of Complement Biology, New York Blood Center, New York, NY., Zhang H; Laboratory of Membrane Biology, New York Blood Center, New York, NY., Wang S; Laboratory of Membrane Biology, New York Blood Center, New York, NY., Zhao H; Laboratory of Membrane Biology, New York Blood Center, New York, NY., Bao W; Laboratory of Complement Biology, New York Blood Center, New York, NY., Guo X; Laboratory of Membrane Biology, New York Blood Center, New York, NY., Vinchi F; Laboratory of Iron Research, New York Blood Center, New York, NY., Lobo C; Laboratory of Blood Borne Parasites, New York Blood Center, New York, NY., Shi P; Sickle Cell Clinical Research Program, New York Blood Center, New York, NY., Mendelson A; Laboratory of Stem Cell Biology and Engineering Research, New York Blood Center, New York, NY., Luchsinger L; Laboratory of Stem Cell Regenerative Research, New York Blood Center, New York, NY., Zhong H; Laboratory of Immune Regulation, New York Blood Center, New York, NY., Yazdanbakhsh K; Laboratory of Complement Biology, New York Blood Center, New York, NY., An X; Laboratory of Membrane Biology, New York Blood Center, New York, NY.

Publikováno v: Blood [Blood] 2024 Mar 14; Vol. 143 (11), pp. 1018-1031.

Author Correction: Consensus Statement on the definition and classification of metabolic hyperferritinaemia.

Autor: Valenti L; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy. luca.valenti@unimi.it.; Biological Resource Center and Precision Medicine Lab, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Milan, Italy. luca.valenti@unimi.it.; Department of Transfusion Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Milan, Italy. luca.valenti@unimi.it., Corradini E; Department of Medical and Surgical Sciences, Università degli Studi di Modena e Reggio Emilia, Modena, Italy. elena.corradini75@unimore.it.; Internal Medicine and Centre for Hemochromatosis and Hereditary Liver Diseases, Azienda Ospedaliero-Universitaria di Modena-Policlinico, Modena, Italy. elena.corradini75@unimore.it., Adams LA; Medical School, University of Western Australia, Perth, Australia., Aigner E; First Department of Medicine, University Clinic Salzburg, Paracelsus Medical University Salzburg, Salzburg, Austria., Alqahtani S; Royal Clinics and Gastroenterology and Hepatology, King Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.; Division of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA., Arrese M; Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Bardou-Jacquet E; University of Rennes, UMR1241, CHU Rennes, National Reference Center for Hemochromatosis and iron metabolism disorder, INSERM CIC1414, Rennes, France., Bugianesi E; Department of Medical Sciences, Division of Gastroenterology, University of Turin, Turin, Italy., Fernandez-Real JM; Department of Diabetes, Endocrinology and Nutrition, Dr Josep Trueta University Hospital, Girona, Spain.; Department of Medical Sciences, Faculty of Medicine, Girona University, Girona, Spain.; Nutrition, Eumetabolism and Health Group, Girona Biomedical Research Institute (IdibGi), Girona, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain., Girelli D; Section of Internal Medicine, Department of Medicine, University of Verona, Policlinico Giambattista Rossi, Verona, Italy., Hagström H; Division of Hepatology, Department of Upper GI Diseases, Karolinska University Hospital, Stockholm, Sweden., Henninger B; Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria., Kowdley K; Liver Institute Northwest, Seattle, WA, USA.; Elson S. Floyd College of Medicine, Washington State University, Seattle, WA, USA., Ligabue G; Department of Medical and Surgical Sciences, Università degli Studi di Modena e Reggio Emilia, Modena, Italy.; Division of Radiology, Ospedale di Sassuolo S.p.A, Sassuolo, Modena, Italy., McClain D; Wake Forest School of Medicine, Winston Salem, NC, USA.; Department of Veterans Affairs, Salisbury, NC, USA., Lainé F; INSERM CIC1414, Liver Unit, CHU Rennes, Rennes, France., Miyanishi K; Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Japan., Muckenthaler MU; Department of Paediatric Hematology, Oncology and Immunology, University of Heidelberg, Heidelberg, Germany.; Center for Molecular Translational Iron Research, Molecular Medicine Partnership Unit, European Molecular Biology Laboratory, Heidelberg, Germany.; German Centre for Cardiovascular Research, Partner Site Heidelberg, Heidelberg, Germany., Pagani A; Regulation of Iron Metabolism Unit, Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, Milan, Italy., Pedrotti P; Laboratorio di RM Cardiaca Cardiologia 4, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Pietrangelo A; Department of Medical and Surgical Sciences, Università degli Studi di Modena e Reggio Emilia, Modena, Italy.; Internal Medicine and Centre for Hemochromatosis and Hereditary Liver Diseases, Azienda Ospedaliero-Universitaria di Modena-Policlinico, Modena, Italy., Prati D; Department of Transfusion Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Milan, Italy., Ryan JD; Hepatology Unit, Beaumont Hospital, RCSI University of Medicine and Health Sciences, Dublin, Ireland., Silvestri L; Regulation of Iron Metabolism Unit, Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, Milan, Italy., Spearman CW; Division of Hepatology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Stål P; Division of Hepatology, Department of Upper GI Diseases, Karolinska University Hospital, Stockholm, Sweden., Tsochatzis EA; UCL Institute for Liver and Digestive Health, Royal Free Hospital and UCL, London, UK., Vinchi F; Iron Research Laboratory, Lindsley F.Kimball Research Institute, New York Blood Center, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Zheng MH; NAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China., Zoller H; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria.; Doppler Laboratory on Iron and Phosphate Biology, Innsbruck, Austria.

Publikováno v: Nature reviews. Endocrinology [Nat Rev Endocrinol] 2024 Mar; Vol. 20 (3), pp. 185.