Zobrazeno 1 - 10 of 132 pro vyhledávání: '"Vincenzo Zappia"'
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Akademický článek
Protein isoaspartate methyltransferase prevents apoptosis induced by oxidative stress in endothelial cells: role of Bcl-Xl deamidation and methylation.
Autor: Amelia Cimmino, Rosanna Capasso, Fabbri Muller, Irene Sambri, Lucia Masella, Marianna Raimo, Maria Luigia De Bonis, Stefania D'Angelo, Vincenzo Zappia, Patrizia Galletti, Diego Ingrosso
Publikováno v: PLoS ONE, Vol 3, Iss 9, p e3258 (2008)
BACKGROUND:Natural proteins undergo in vivo spontaneous post-biosynthetic deamidation of specific asparagine residues with isoaspartyl formation. Deamidated-isomerized molecules are both structurally and functionally altered. The enzyme isoaspartyl p
Externí odkaz: https://doaj.org/article/fb687f48569f4a148a1aee47bab3fc1a
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2
Data from Retinoic Acid Induces p27Kip1 Nuclear Accumulation by Modulating Its Phosphorylation
Autor: Fulvio Della Ragione, Vincenzo Zappia, Achille Iolascon, Debora Bencivenga, Alfonso Giovane, Adriana Oliva, Stefania Indaco, Maria Criscuolo, Valeria Cucciolla, Adriana Borriello
All-trans-retinoic acid (ATRA), the most biologically active metabolite of vitamin A, controls cell proliferation, apoptosis, and differentiation depending on the cellular context. These activities point to ATRA as a candidate for cancer therapy. A p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541b0173cca16e6530c1f9a3d810ddc8
https://doi.org/10.1158/0008-5472.c.6494957
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5
The Role of Iron Toxicity in Oxidative Stress-induced Cellular Degeneration in Down Syndrome: Protective Effects of Phenolic Antioxidants
Autor: Generoso Andria, Iris Scala, Barbara Granese, Vincenzo Zappia, Caterina Manna, Lidia Tagliafierro
Publikováno v: Current Nutrition & Food Science. 8:206-212
A chronic oxidative stress is a typical feature of Down Syndrome (DS, trisomy 21), the major cause of mental disability in humans. In this paper we report the first experimental evidence that iron toxicity may contribute to build up the pro-oxidative
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152d38b4a85ddda0ad4b8bdebddfc841
https://doi.org/10.2174/157340112802651176
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6
Protective Effect of Polyphenols from Glycyrrhiza glabra Against Oxidative Stress in Caco-2 Cells
Autor: Vincenzo Zappia, Alessandra Morana, Patrizia Galletti, Anna Salvatore, Stefania D'Angelo
Publikováno v: Journal of medicinal food 12 (2009): 1326–1333. doi:10.1089/jmf.2008.0285
info:cnr-pdr/source/autori:D'Angelo S.; Morana A.; Salvatore A.; Zappia V.; Galletti P./titolo:Protective effect of polyphenols from %2FGlycyrrhiza glabra%2F against oxidative stress in Caco-2 cells/doi:10.1089%2Fjmf.2008.0285/rivista:Journal of medicinal food/anno:2009/pagina_da:1326/pagina_a:1333/intervallo_pagine:1326–1333/volume:12
In the present article, we have investigated the antioxidant properties of methanolic liquorice polyphenol extracts (LPE(s)). Polyphenol extraction was performed with 60% and 100% methanol. Analysis of LPE(s) by thin-layer chromatography revealed tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7b282371627e292b8d9df233d595fc
https://doi.org/10.1089/jmf.2008.0285
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7
Elektronická kniha
Advances in Nutrition and Cancer
Autor: Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione
This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed “nutrition and cancer” from different perspectives and on the
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8
Histone deacetylase inhibitors upregulate p57Kip2 level by enhancing its expression through Sp1 transcription factor
Autor: Anna Chiara Scudieri, Valeria Cucciolla, Annunziata Tramontano, Vincenzo Zappia, Debora Bencivenga, Adriana Oliva, Adriana Borriello, Maria Criscuolo, Fulvio Della Ragione, Antonio Agostino Sinisi
Publikováno v: Carcinogenesis. 29:560-567
Histone deacetylase inhibitors (HDACIs) represent a new class of targeted anticancer agents. Here, we evaluate the effects of butyrate (BuA) and other HDACIs on p57(Kip2), a cyclin-dependent kinase inhibitor (cki). We observed that inhibitors of clas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99219b9c37e6dc971405e54395c6285
https://doi.org/10.1093/carcin/bgn010
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9
Accumulation of altered aspartyl residues in erythrocyte proteins from patients with Down's syndrome
Autor: Marianna Raimo, Alvara Sorrentino, Generoso Andria, Patrizia Galletti, Iris Scala, Diego Ingrosso, Antimo D'Aniello, Stefania D'Angelo, Vincenzo Zappia, Maria Luigia De Bonis
Publikováno v: FEBS Journal. 274:5263-5277
Spontaneous protein deamidation of labile Asn residues, generating L-isoaspartates and D-aspartates, is associated with cell aging and is enhanced by an oxidative microenvironment; to minimize the damage, the isoaspartate residues can be 'repaired' b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bba2f0740f3fac63d8b1f00bcd8dfa28
https://doi.org/10.1111/j.1742-4658.2007.06048.x
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10
Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus
Autor: Vincenzo Zappia, Rosa Anna Siciliano, Giovanna Cacciapuoti, Sabrina Gorassini, Marina Porcelli, Virginia Carbone, Maria Fiorella Mazzeo
Publikováno v: FEBS Journal. 274:2482-2495
We report here the characterization of the first mammalian-like purine nucleoside phosphorylase from the hyperthermophilic archaeon Pyrococcus furiosus (PfPNP). The gene PF0853 encoding PfPNP was cloned and expressed in Escherichia coli and the recom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f95e9b9eddf0e0c9f0aaf0a1223a8e93
https://doi.org/10.1111/j.1742-4658.2007.05784.x
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