Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vincenzo Pierotti"'
Autor:
Jere P. Segrest, Martin K. Jones, Vinod K. Mishra, Vincenzo Pierotti, Stephen H. Young, Jan Borén, Thomas L. Innerarity, Nassrin Dashti
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 1, Pp 85-102 (1998)
Development of a computer program called LOCATE allowed us to show that human apolipoprotein B-100 is composed of five domains, NH2-α1-β1-α2-β2-α3-COOH, enriched, alternately, in amphipathic α helixes and amphipathic β strands. Using updated v
Externí odkaz:
https://doaj.org/article/2d73ccb81d8e47a884448c506e3f1de6
Autor:
Alain Thuret, Olivier Muntaner, Mark G.H. Scott, Vincenzo Pierotti, Julie A. Pitcher, Stephano Marullo, Hélène Storez, Catherine Labbé-Jullié, Erika Lindberg
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2006, 26, pp.3432-45. 〈10.1128/MCB.26.9.3432-3445.2006〉
Molecular and Cellular Biology, American Society for Microbiology, 2006, 26, pp.3432-45. 〈10.1128/MCB.26.9.3432-3445.2006〉
14 pages; beta-Arrestins (betaarr) are multifunctional adaptor proteins that can act as scaffolds for G protein-coupled receptor activation of mitogen-activated protein kinases (MAPK). Here, we identify the actin-binding and scaffolding protein filam
Autor:
Stefano Marullo, Erwann Le Rouzic, Mark G.H. Scott, Axel Périanin, Vincenzo Pierotti, Alexandre Benmerah, Serge Benichou, Hervé Enslen
Publikováno v:
Journal of Biological Chemistry. 277:37693-37701
β-arrestins (βarrs) are two highly homologous proteins that uncouple G protein-coupled receptors from their cognate G proteins, serve as adaptor molecules linking G protein-coupled receptors to clathrin-coat components (AP-2 complex and clathrin),
Autor:
Rosemary L. Walzem, Constance H. Zlot, Murielle M. Véniant, David A. Dichek, Vincenzo Pierotti, Joachim Herz, Stephen G. Young, Robert M. Driscoll
Publikováno v:
Journal of Clinical Investigation. 102:1559-1568
The role of the low density lipoprotein receptor (LDLR) in the clearance of apo-B48-containing lipoproteins and the role of the LDLR-related protein (LRP) in the removal of apo-B100-containing lipoproteins have not been clearly defined. To address th
Autor:
Jan Borén, Martin K. Jones, Thomas L. Innerarity, Stephen H. Young, Vinod K. Mishra, Nassrin Dashti, Jere P. Segrest, Vincenzo Pierotti
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 1, Pp 85-102 (1998)
Development of a computer program called LOCATE allowed us to show that human apolipoprotein B-100 is composed of five domains, NH2-α1-β1-α2-β2-α3-COOH, enriched, alternately, in amphipathic α helixes and amphipathic β strands. Using updated v
Autor:
Stephen G. Young, Sally P.A. McCormick, Lars Bo Nielsen, Carmen Tam, Vincenzo Pierotti, Hiroaki Shizuya, Michael D. Gunn
Publikováno v:
Journal of Biological Chemistry. 272:29752-29758
We reported previously that ~80-kilobase pair (kb) P1 bacteriophage clones spanning either the human or mouse apoB gene (clones p158 and p649, respectively) confer apoB expression in the liver of transgenic mice, but not in the intestine. We hypothes
Autor:
Renee Stokowski, Stephen G. Young, Robert V. Farese, Dennis Huszar, Laura M. Flynn, Candace M. Cham, Maret G. Traber, Jeanne F. Loring, Vincenzo Pierotti, Sandra L. Ruland, Murielle M. Véniant
Publikováno v:
Proceedings of the National Academy of Sciences. 93:6393-6398
Apolipoprotein (apo)-B is found in two forms in mammals: apo-B100, which is made in the liver and the yolk sac, and apo-B48, a truncated protein made in the intestine. To provide models for understanding the physiologic purpose for the two forms of a
Autor:
David S. Grass, Vincenzo Pierotti, Sally P.A. McCormick, Stephen G. Young, Andrew J. Connolly, Jan Borén, Laura M. Flynn, Murielle M. Véniant, Jennifer K. Ng
Publikováno v:
Journal of Biological Chemistry. 271:11963-11970
An 87-kilobase (kb) P1 bacteriophage clone (p649) spanning the mouse apolipoprotein (apo) B gene was used to generate transgenic mice that express high levels of mouse apoB. Plasma levels of apoB, low density lipoprotein cholesterol, and low density
Publikováno v:
Proceedings of the National Academy of Sciences. 89:11431-11435
We examined a mutant human apolipoprotein B (apoB) allele that causes hypobetalipoproteinemia and has a single cytosine deletion in exon 26. This frameshift mutation was associated with the synthesis of a truncated apoB protein of the predicted size;
Autor:
Murielle M. Véniant, David A. Sanan, Stephen G. Young, Candace M. Cham, Vincenzo Pierotti, Dale L. Newland, Rosemary L. Walzem
Publikováno v:
The Journal of clinical investigation. 100(1)
All classes of lipoproteins considered to be atherogenic contain apo-B100 or apo-B48. However, there is a distinct paucity of data regarding whether lipoproteins containing apo-B48 or apo-B100 differ in their intrinsic ability to promote the developm