Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Vincenzo Flati"'
Autor:
Irene Fasciani, Francesco Petragnano, Ziming Wang, Ruairidh Edwards, Narasimha Telugu, Ilaria Pietrantoni, Ulrike Zabel, Henrik Zauber, Marlies Grieben, Maria E Terzenidou, Jacopo Di Gregorio, Cristina Pellegrini, Silvano Santini, Anna R Taddei, Bärbel Pohl, Stefano Aringhieri, Marco Carli, Gabriella Aloisi, Francesco Marampon, Eve Charlesworth, Alexandra Roman, Sebastian Diecke, Vincenzo Flati, Franco Giorgi, Fernanda Amicarelli, Andrew B Tobin, Marco Scarselli, Kostas Tokatlidis, Mario Rossi, Martin J Lohse, Paolo Annibale, Roberto Maggio
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002582 (2024)
Muscarinic acetylcholine receptors are prototypical G protein-coupled receptors (GPCRs), members of a large family of 7 transmembrane receptors mediating a wide variety of extracellular signals. We show here, in cultured cells and in a murine model,
Externí odkaz:
https://doaj.org/article/55337ca4f8c84555b649a08804c2bd5c
Autor:
Jacopo Di Gregorio, Laura Di Giuseppe, Sara Terreri, Michela Rossi, Giulia Battafarano, Olivia Pagliarosi, Vincenzo Flati, Andrea Del Fattore
Publikováno v:
Cells, Vol 13, Iss 6, p 537 (2024)
The identification of new therapeutic targets and the development of innovative therapeutic approaches are the most important challenges for osteosarcoma treatment. In fact, despite being relatively rare, recurrence and metastatic potential, particul
Externí odkaz:
https://doaj.org/article/5580a65d10ff4f8bb494924e1d203093
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151225- (2022)
Metabolic alterations have been observed in many cancer types. The deregulated metabolism has thus become an emerging hallmark of the disease, where the metabolism is frequently rewired to aerobic glycolysis. This has led to the concept of “metabol
Externí odkaz:
https://doaj.org/article/5bbde54b4ecb4e6a8bc4af0d594f1282
Autor:
Ivana Cacciatore, Sonia Spalletta, Annalisa Di Rienzo, Vincenzo Flati, Erika Fornasari, Laura Pierdomenico, Piero Del Boccio, Silvia Valentinuzzi, Erica Costantini, Elena Toniato, Stefano Martinotti, Carmela Conte, Antonio Di Stefano, Iole Robuffo
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 340 (2023)
(1) Background: Obesity, a complex metabolic disease resulting from an imbalance between food consumption and energy expenditure, leads to an increase in adipocytes and chronic inflammatory conditions. The aim of this paper was to synthesize a small
Externí odkaz:
https://doaj.org/article/cf678bff4bc14b73ac2165405fd2fc1c
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2935 (2022)
The mammalian target of rapamycin (mTOR) signaling plays a critical role in cell homeostasis, growth and survival. Here, we investigated the localization of the main mTOR signaling proteins in the organ of Corti of normal-hearing and deafened guinea
Externí odkaz:
https://doaj.org/article/4b7515fb4af9464c80f26ce0ca590b81
Autor:
Annamaria Tisi, Fanny Pulcini, Giulia Carozza, Vincenzo Mattei, Vincenzo Flati, Maurizio Passacantando, Cinzia Antognelli, Rita Maccarone, Simona Delle Monache
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1133 (2022)
In this study, we investigated whether cerium oxide nanoparticles (CeO2-NPs), a promising antioxidant nanomaterial, may contrast retinal vascular alterations induced by oxidative damage in vitro and in vivo. For the in vivo experiments, the light dam
Externí odkaz:
https://doaj.org/article/13119376de6946f1a10f4367d679561a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/2578efb8871b4edc96ad1ea45361fd0f
Autor:
Jacopo Di Gregorio, Iole Robuffo, Sonia Spalletta, Giulia Giambuzzi, Vincenzo De Iuliis, Elena Toniato, Stefano Martinotti, Pio Conti, Vincenzo Flati
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Fibrosis is a chronic and progressive disorder characterized by excessive deposition of extracellular matrix, which leads to scarring and loss of function of the affected organ or tissue. Indeed, the fibrotic process affects a variety of organs and t
Externí odkaz:
https://doaj.org/article/2d0cfd462ae745d29e81c95336fbae44
Autor:
Annamaria Tisi, Vincenzo Flati, Simona Delle Monache, Luca Lozzi, Maurizio Passacantando, Rita Maccarone
Publikováno v:
Cells, Vol 9, Iss 7, p 1617 (2020)
Retinal pigment epithelium (RPE) dysfunction and degeneration underlie the development of age-related macular degeneration (AMD), which is the leading cause of blindness worldwide. In this study, we investigated whether cerium oxide nanoparticles (Ce
Externí odkaz:
https://doaj.org/article/f65c4424211c4b82a18a9b5d442352e8
Autor:
Giovanni Corsetti, Evasio Pasini, Claudia Romano, Riccardo Calvani, Anna Picca, Emanuele Marzetti, Vincenzo Flati, Francesco S. Dioguardi
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Objective: Inadequate protein intake can impair protein balance thus leading to skeletal muscle atrophy, impaired body growth, and functional decline. Foods provide both non-essential (NEAAs) and essential amino acids (EAAs) that may convey different
Externí odkaz:
https://doaj.org/article/ae29573021fc4961ba549d726824bcf3