Výsledky vyhledávání - "Vincenzo Conte"

Akademický článek

Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy

Autor: Giorgia Moschetti, Giada Amodeo, Daniela Maftei, Roberta Lattanzi, Patrizia Procacci, Patrizia Sartori, Gianfranco Balboni, Valentina Onnis, Vincenzo Conte, Alberto Panerai, Paola Sacerdote, Silvia Franchi

Publikováno v: Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-16 (2019)

Abstract Background Neuropathy is a dose-limiting side effect of many chemotherapeutics, including bortezomib. The mechanisms underlying this condition are not fully elucidated even if a contribution of neuroinflammation was suggested. Here, we inves

Externí odkaz: https://doaj.org/article/73ca182d66fa46babfb26064d160bd30

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Akademický článek

Activity of Experimental Mouthwashes and Gels Containing DNA-RNA and Bioactive Molecules against the Oxidative Stress of Oral Soft Tissues: The Importance of Formulations. A Bioreactor-Based Reconstituted Human Oral Epithelium Model

Autor: Andrei C. Ionescu, Elena Vezzoli, Vincenzo Conte, Patrizia Sartori, Patrizia Procacci, Eugenio Brambilla

Publikováno v: Molecules, Vol 26, Iss 10, p 2976 (2021)

Background: DNA-RNA compounds have shown promising protection against cell oxidative stress. This study aimed to assess the cytotoxicity, protective, or preventive effect of different experimental formulations on oral epithelia’s oxidative stress i

Externí odkaz: https://doaj.org/article/0d3a7f42adc34c84bb2290e86e208b1f

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Akademický článek

Acid Sphingomyelinase Downregulation Enhances Mitochondrial Fusion and Promotes Oxidative Metabolism in a Mouse Model of Melanoma

Autor: Marco Coazzoli, Alessandra Napoli, Paulina Roux-Biejat, Clara De Palma, Claudia Moscheni, Elisabetta Catalani, Silvia Zecchini, Vincenzo Conte, Matteo Giovarelli, Sonia Caccia, Patrizia Procacci, Davide Cervia, Emilio Clementi, Cristiana Perrotta

Publikováno v: Cells, Vol 9, Iss 4, p 848 (2020)

Melanoma is the most severe type of skin cancer. Its unique and heterogeneous metabolism, relying on both glycolysis and oxidative phosphorylation, allows it to adapt to disparate conditions. Mitochondrial function is strictly interconnected with mit

Externí odkaz: https://doaj.org/article/016cb17a6f684d1893736ce387b738e6

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The Antagonism of the Prokineticin System Counteracts Bortezomib Induced Side Effects: Focus on Mood Alterations

Autor: Silvia Franchi, Benedetta Verduci, Vincenzo Conte, Patrizia Sartori, Paola Sacerdote, Gianfranco Balboni, Giada Amodeo, Patrizia Procacci

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10256, p 10256 (2021)

The development of neuropathy and of mood alterations is frequent after chemotherapy. These complications, independent from the antitumoral mechanism, are interconnected due to an overlapping in their processing pathways and a common neuroinflammator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e3cb795007b552f46015cdd0d8c745

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Autor: Eugenio Brambilla, Patrizia Procacci, Patrizia Sartori, Andrei C. Ionescu, Elena Vezzoli, Vincenzo Conte

Publikováno v: Molecules
Volume 26
Issue 10
Molecules, Vol 26, Iss 2976, p 2976 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62010fd7e681df7476dd2d127168c4e4

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Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy

Autor: Patrizia Procacci, Gianfranco Balboni, Vincenzo Conte, Giada Amodeo, Roberta Lattanzi, Valentina Onnis, Daniela Maftei, Paola Sacerdote, Silvia Franchi, Alberto E. Panerai, Giorgia Moschetti, Patrizia Sartori

Publikováno v: Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-16 (2019)
Journal of Neuroinflammation

Background Neuropathy is a dose-limiting side effect of many chemotherapeutics, including bortezomib. The mechanisms underlying this condition are not fully elucidated even if a contribution of neuroinflammation was suggested. Here, we investigated t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c31d834438a7af8c4850e9d402102b7
https://doi.org/10.1186/s12974-019-1461-0

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Long term effects of lipopolysaccharide on satellite glial cells in mouse dorsal root ganglia

Autor: Menachem Hanani, Patrizia Procacci, Patrizia Sartori, E. Blum, Vincenzo Conte

Publikováno v: Experimental Cell Research. 350:236-241

Lipopolysaccharide (LPS) has been used extensively to study neuroinflammation, but usually its effects were examined acutely (24h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb8cefe490251b5171bcd4f6eb6db5d
https://doi.org/10.1016/j.yexcr.2016.11.026

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3D-spheroids: What can they tell us about pancreatic ductal adenocarcinoma cell phenotype?

Autor: Vincenzo Conte, Chiarella Sforza, Patrizia Procacci, Nicoletta Gagliano, Alessandra Menon, Michele Sommariva, Patrizia Sartori

Publikováno v: Experimental cell research. 357(2)

We aimed at analyzing the effect of the 3D-arrangement on the expression of some genes and proteins which play a key role in pancreatic adenocarcinoma (PDAC) progression in HPAF-II, HPAC and PL45 PDAC cells cultured in either 2D-monolayers or 3D-sphe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c8e6cf3bf8f170152c4e013b563540
https://pubmed.ncbi.nlm.nih.gov/28571915

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