Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Vincenzo, Carginale"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2092-2098 (2022)
Carbonic anhydrases, catalysing the reversible CO2 hydration reaction, contribute in all living organisms to the maintenance of stable metabolic functions depending on intracellular concentrations of carbon dioxide, bicarbonate, and protons. Recent s
Externí odkaz:
https://doaj.org/article/c24a82beb06d4e3fbdd07d88c98bb8a8
Autor:
Viviana De Luca, Andrea Angeli, Alessio Nocentini, Paola Gratteri, Silvia Pratesi, Damiano Tanini, Vincenzo Carginale, Antonella Capperucci, Claudiu T. Supuran, Clemente Capasso
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 971 (2024)
The implementation of innovative approaches is crucial in an ongoing endeavor to mitigate the impact of COVID-19 pandemic. The present study examines the strategic application of the SARS-CoV-2 Main Protease (Mpro) as a prospective instrument in the
Externí odkaz:
https://doaj.org/article/b3acc9c8f6664737adbe3c121f289e9c
Autor:
Viviana De Luca, Andrea Angeli, Valeria Mazzone, Claudia Adelfio, Vincenzo Carginale, Andrea Scaloni, Fabrizio Carta, Silvia Selleri, Claudiu T. Supuran, Clemente Capasso
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 62-68 (2022)
Warm-blooded animals may have Malassezia pachydermatis on healthy skin, but changes in the skin microenvironment or host defences induce this opportunistic commensal to become pathogenic. Malassezia infections in humans and animals are commonly treat
Externí odkaz:
https://doaj.org/article/5aced237767d4c40b6a1967628837f35
Autor:
Viviana De Luca, Andrea Petreni, Vincenzo Carginale, Andrea Scaloni, Claudiu T. Supuran, Clemente Capasso
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1000-1006 (2021)
We here report a study on the activation of the ι-class bacterial CA from Burkholderia territorii (BteCAι). This protein was recently characterised as a zinc-dependent enzyme that shows a significant catalytic activity (kcat 3.0 × 105 s−1) for t
Externí odkaz:
https://doaj.org/article/c1a66d0c992d4706b6b573900b778c4e
Autor:
Giovanna Salbitani, Sonia Del Prete, Francesco Bolinesi, Olga Mangoni, Viviana De Luca, Vincenzo Carginale, William A. Donald, Claudiu T. Supuran, Simona Carfagna, Clemente Capasso
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 913-920 (2020)
There is significant interest in increasing the microalgal efficiency for producing high-quality products that are commonly used as food additives in nutraceuticals. Some natural substances that can be extracted from algae include lipids, carbohydrat
Externí odkaz:
https://doaj.org/article/4d6798ed6c0b463a89fe3c67941411f7
Autor:
Maurizio Ronci, Sonia Del Prete, Valentina Puca, Simone Carradori, Vincenzo Carginale, Raffaella Muraro, Gabriella Mincione, Antonio Aceto, Francesca Sisto, Claudiu T. Supuran, Rossella Grande, Clemente Capasso
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 189-195 (2019)
The genome of Helicobacter pylori encodes for carbonic anhydrases (CAs, EC 4.2.1.1) belonging to the α- and β-CA classes, which together with urease, have a pivotal role in the acid acclimation of the microorganism within the human stomach. Recentl
Externí odkaz:
https://doaj.org/article/8ace7ed4bfe8464f83459cf0f05b1772
Autor:
Sonia Del Prete, Rosa Merlo, Anna Valenti, Rosanna Mattossovich, Mosè Rossi, Vincenzo Carginale, Claudiu T. Supuran, Giuseppe Perugino, Clemente Capasso
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 946-954 (2019)
Carbonic anhydrases (CAs, EC 4.2.1.1) are a superfamily of ubiquitous metalloenzymes present in all living organisms on the planet. They are classified into seven genetically distinct families and catalyse the hydration reaction of carbon dioxide to
Externí odkaz:
https://doaj.org/article/65113c1a6f1b4516b7abd372a652a5f3
Autor:
Rosa Merlo, Sonia Del Prete, Anna Valenti, Rosanna Mattossovich, Vincenzo Carginale, Claudiu T. Supuran, Clemente Capasso, Giuseppe Perugino
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 490-499 (2019)
The use of natural systems, such as outer membrane protein A (OmpA), phosphoporin E (PhoE), ice nucleation protein (INP), etc., has been proved very useful for the surface exposure of proteins on the outer membrane of Gram-negative bacteria. These st
Externí odkaz:
https://doaj.org/article/eaab4d0483a6489e946d1ec30d79fffa
Autor:
Alessandra Rogato, Sonia Del Prete, Alessio Nocentini, Vincenzo Carginale, Claudiu T. Supuran, Clemente Capasso
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 510-518 (2019)
Carbonic anhydrases (CAs) are ubiquitous metalloenzymes, which started to be investigated in detail in pathogenic, as well as non-pathogenic species since their pivotal role is to accelerate the physiological CO2 hydration/dehydration reaction signif
Externí odkaz:
https://doaj.org/article/20cec3a1c55c4bfe9648e5bc3c265d57
Autor:
Cristina Campestre, Viviana De Luca, Simone Carradori, Rossella Grande, Vincenzo Carginale, Andrea Scaloni, Claudiu T. Supuran, Clemente Capasso
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Our understanding of the function of bacterial carbonic anhydrases (CAs, EC 4.2.1.1) has increased significantly in the last years. CAs are metalloenzymes able to modulate CO2, HCO3– and H+ concentration through their crucial role in catalysis of r
Externí odkaz:
https://doaj.org/article/5a33f61bdfe44e799d0a22827aa9d1c9