Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Vincenzina Nicolia"'
Autor:
Noemi Monti, Rosaria A. Cavallaro, Andrea Stoccoro, Vincenzina Nicolia, Sigfrido Scarpa, Gabor G. Kovacs, Maria Teresa Fiorenza, Marco Lucarelli, Eleonora Aronica, Isidre Ferrer, Fabio Coppedè, Aron M. Troen, Andrea Fuso
Publikováno v:
Epigenetics, Vol 15, Iss 8, Pp 781-799 (2020)
The Presenilin1 (PSEN1) gene encodes the catalytic peptide of the γ-secretase complex, a key enzyme that cleaves the amyloid-β protein precursor (AβPP), to generate the amyloid-β (Aβ) peptides, involved in Alzheimer’s Disease (AD). Other subst
Externí odkaz:
https://doaj.org/article/c0fb2fc80ff8444b929a6cd06863b2c1
Autor:
Rosaria A. Cavallaro, Vincenzina Nicolia, Maria Teresa Fiorenza, Sigfrido Scarpa, Andrea Fuso
Publikováno v:
Antioxidants, Vol 6, Iss 4, p 76 (2017)
Recent evidence emphasizes the role of dysregulated one-carbon metabolism in Alzheimer’s Disease (AD). Exploiting a nutritional B-vitamin deficiency paradigm, we have previously shown that PSEN1 and BACE1 activity is modulated by one-carbon metabol
Externí odkaz:
https://doaj.org/article/b8bcadd6493b4fd1a91ecb4f45df5123
Autor:
Gabor G. Kovacs, Vincenzina Nicolia, Fabio Coppedè, Eleonora Aronica, Rosaria A. Cavallaro, Sigfrido Scarpa, Maria Teresa Fiorenza, Marco Lucarelli, Andrea Stoccoro, Noemi Monti, Andrea Fuso, Aron M. Troen, Isidre Ferrer
Publikováno v:
Epigenetics
EPIGENETICS, 15(8), 781-799. Landes Bioscience
EPIGENETICS, 15(8), 781-799. Landes Bioscience
The Presenilin1 (PSEN1) gene encodes the catalytic peptide of the γ-secretase complex, a key enzyme that cleaves the amyloid-β protein precursor (AβPP), to generate the amyloid-β (Aβ) peptides, involved in Alzheimer’s Disease (AD). Other subst
Autor:
Jacopo Gervasoni, Sigfrido Scarpa, Claudia Desiderio, Bruno Giardina, Silvia Persichilli, Rosaria A. Cavallaro, Vincenzina Nicolia, Alessandra Di Napoli, Andrea Fuso
Publikováno v:
Journal of Alzheimer's disease 44 (2015): 1323–1331. doi:10.3233/JAD-142391
info:cnr-pdr/source/autori:Persichilli, Silvia; Gervasoni, Jacopo; Di Napoli, Alessandra; Fuso, Andrea; Nicolia, Vincenzina; Giardina, Bruno; Scarpa, Sigfrido; Desiderio, Claudia; Cavallaro, Rosaria A./titolo:Plasma Thiols Levels in Alzheimer's Disease Mice under Diet-Induced Hyperhomocysteinemia: Effect of S-Adenosylmethionine and Superoxide-Dismutase Supplementation/doi:10.3233%2FJAD-142391/rivista:Journal of Alzheimer's disease/anno:2015/pagina_da:1323/pagina_a:1331/intervallo_pagine:1323–1331/volume:44
info:cnr-pdr/source/autori:Persichilli, Silvia; Gervasoni, Jacopo; Di Napoli, Alessandra; Fuso, Andrea; Nicolia, Vincenzina; Giardina, Bruno; Scarpa, Sigfrido; Desiderio, Claudia; Cavallaro, Rosaria A./titolo:Plasma Thiols Levels in Alzheimer's Disease Mice under Diet-Induced Hyperhomocysteinemia: Effect of S-Adenosylmethionine and Superoxide-Dismutase Supplementation/doi:10.3233%2FJAD-142391/rivista:Journal of Alzheimer's disease/anno:2015/pagina_da:1323/pagina_a:1331/intervallo_pagine:1323–1331/volume:44
Widely confirmed reports were published on association between hyperhomocysteinemia, B vitamin deficiency, oxidative stress, and amyloid-beta in Alzheimer's disease (AD). Homocysteine, cysteine, cysteinylglycine and glutathione are metabolically inte
Autor:
Rosaria A. Cavallaro, Mauro Maccarrone, Sigfrido Scarpa, Vincenzina Nicolia, Andrea Fuso, Isidre Ferrer, Irene López-González
By means of functional genomics analysis, we recently described the mRNA expression profiles of various genes involved in the neuroinflammatory response in the brains of subjects with late-onset Alzheimer Disease (LOAD). Some of these genes, namely i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1366f271d392e00ee4ff98b8fb795ff
http://hdl.handle.net/11573/1283638
http://hdl.handle.net/11573/1283638
Autor:
Maria Teresa Fiorenza, Gabor G. Kovacs, Viviana Ciraci, Sonia Canterini, Vincenzina Nicolia, Sigfrido Scarpa, Giampiero Palladino, Franco Mangia, Andrea Fuso
Recent evidence highlights the protective role of reelin against amyloid β (Aβ)-induced synaptic dysfunction and cognitive impairment in Alzheimer disease (AD). In this study, exploiting TgCRND8 mice that overexpress a mutant form of amyloid β pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba74c2cff6ba1a327518c13905e44fd
http://hdl.handle.net/11573/908476
http://hdl.handle.net/11573/908476
Autor:
Sigfrido Scarpa, Viviana Ciraci, Andrea Fuso, Rosaria A. Cavallaro, Isidre Ferrer, Vincenzina Nicolia
Publikováno v:
Current Alzheimer research. 14(7)
Background: The GSK3β has been associated to pathological functions in neurodegenerative diseases. This kinase is involved in hyperphosphorylation of microtubule-associated tau protein, leading to aggregation andformation of NFTs. It has clearly bee
Publikováno v:
Behavioural Brain Research. 237:223-229
Small GTPases of the Rho family, including Rho, Rac and CDC42 subfamilies, play key role in neural connectivity and cognition. The pharmacological modulation of these regulatory proteins is associated with enhancement of learning and memory. We sough
Autor:
Laura Ricceri, Sigfrido Scarpa, Fabrizio D'Anselmi, Pierpaolo Coluccia, Vincenzina Nicolia, Andrea Fuso, Gemma Calamandrei, Rosaria A. Cavallaro
Publikováno v:
Molecular and Cellular Neuroscience. 37:731-746
Etiological and molecular studies on the sporadic form of Alzheimer's disease have yet to determine the underlying mechanisms of neurodegeneration. Hyperhomocysteinemia is associated with Alzheimer's disease, and has been hypothesized to promote neur
Publikováno v:
Experimental Gerontology
Experimental Gerontology, Elsevier, 2015, 68, pp.8-12. ⟨10.1016/j.exger.2014.10.006⟩
Experimental Gerontology, 2015, 68, pp.8-12. ⟨10.1016/j.exger.2014.10.006⟩
Experimental Gerontology, Elsevier, 2015, 68, pp.8-12. ⟨10.1016/j.exger.2014.10.006⟩
Experimental Gerontology, 2015, 68, pp.8-12. ⟨10.1016/j.exger.2014.10.006⟩
International audience; Many different environmental factors (nutrients, pollutants, chemicals, physical activity, lifestyle, physical and mental stress) can modulate epigenetic markers in the developing and adult organism. Epigenetics, in turn, can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a360873afc309a0fd48802287c4a2275
https://hal-riip.archives-ouvertes.fr/pasteur-01182432
https://hal-riip.archives-ouvertes.fr/pasteur-01182432