Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Vincenza D'Angelo"'
Autor:
Emanuela Paldino, Vincenza D’Angelo, Daunia Laurenti, Cecilia Angeloni, Giuseppe Sancesario, Francesca R. Fusco
Publikováno v:
Cells, Vol 9, Iss 10, p 2286 (2020)
Pyroptosis is a type of cell death that is caspase-1 (Casp-1) dependent, which leads to a rapid cell lysis, and it is linked to the inflammasome. We recently showed that pyroptotic cell death occurs in Huntington’s disease (HD). Moreover, we previo
Externí odkaz:
https://doaj.org/article/72afddd4a01943bf848e68cce3a760f3
Autor:
Emanuela Paldino, Antonella Cardinale, Vincenza D’Angelo, Ilaria Sauve, Carmela Giampà, Francesca R. Fusco
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2017)
Poly (ADP-ribose) polymerases (PARPs) are enzymes that catalyze ADP-ribose units transfer from NAD to their substrate proteins. It has been observed that PARP-1 is able to increase both post-ischemic and excitotoxic neuronal death. In fact, we have p
Externí odkaz:
https://doaj.org/article/4f0ea69e429840a1b35391d1040d49a4
Autor:
Enrica Olivola, Mariangela Pierantozzi, Paola Imbriani, Claudio Liguori, Mario Stampanoni Bassi, Marco Conti, Vincenza D'Angelo, Nicola Biagio Mercuri, Alessandro Stefani
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101763 (2014)
In Parkinson's disease (PD), several studies have detected an impaired serotonin (5-HT) pathway, likely affecting both motor and non-motor domains. However, the precise impact of 5-HT impairment is far from established. Here, we have used a HPLC chro
Externí odkaz:
https://doaj.org/article/608df136ea0d490da3923d64045e6737
Autor:
Ada Ledonne, Mariangela Massaro Cenere, Emanuela Paldino, Vincenza D'Angelo, Sebastian Luca D'Addario, Nicolas Casadei, Annalisa Nobili, Nicola Berretta, Francesca R. Fusco, Rossella Ventura, Giuseppe Sancesario, Ezia Guatteo, Nicola Biagio Mercuri
Publikováno v:
Movement disorders : official journal of the Movement Disorder SocietyReferences.
The accumulation of α-synuclein (α-syn) fibrils in intraneuronal inclusions called Lewy bodies and Lewy neurites is a pathological signature of Parkinson's disease (PD). Although several aspects linked to α-syn-dependent pathology (concerning its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59c7acfbed4377d4c74861bd97ba216
https://pubmed.ncbi.nlm.nih.gov/36350188
https://pubmed.ncbi.nlm.nih.gov/36350188
Publikováno v:
Cell Death Discovery, Vol 6, Iss 1, Pp 1-12 (2020)
Cell Death Discovery
Cell Death Discovery
Mechanisms of tissue damage in Huntington’s disease involve excitotoxicity, mitochondrial damage, and neuroinflammation, including microglia activation. In the present study, we investigate the role of pyroptosis process in the striatal neurons of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e916f57e98c9a3a5d1886c8d856795
http://link.springer.com/article/10.1038/s41420-020-00293-z
http://link.springer.com/article/10.1038/s41420-020-00293-z
Autor:
Paola Platania, Paola Bonsi, Ilham El Atiallah, Tommaso Schirinzi, Paola Imbriani, Giulia Di Lazzaro, Vincenza D'Angelo, Antonio Pisani, Vito Luigi Colona, Giuseppina Martella, Chiara Salimei, Simona Scalise, Nicola Biagio Mercuri
Publikováno v:
Parkinsonism & Related Disorders. 74:57-63
Introduction:Increasing evidence demonstrates the relevant association between Parkinson's disease (PD) and vascular diseases/risk factors, as well as a worse clinico-pathological progression in those patients with vascular comorbidity. The mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb39708ccf4245ee9b5c7da99e4b3ca4
https://doi.org/10.1016/j.parkreldis.2020.04.004
https://doi.org/10.1016/j.parkreldis.2020.04.004
Autor:
Carmela Giampà, Claudia Balducci, Vincenza D'Angelo, Luisa Artioli, Vladimiro Artuso, Emanuela Paldino, Pietro La Vitola, Gianluigi Forloni, Francesca Fusco
Publikováno v:
Molecular Neurobiology
Mechanisms of tissue damage in Huntington’s disease involve excitotoxicity, mitochondrial damage, and inflammation, including microglia activation. Immunomodulatory and anti-protein aggregation properties of tetracyclines were demonstrated in sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de590871e5430f8a93287355f67602e7
https://doi.org/10.1007/s12035-019-01847-8
https://doi.org/10.1007/s12035-019-01847-8
Autor:
Emanuela Paldino, Vincenza D’angelo, Mariangela Massaro Cenere, Ezia Guatteo, Simone Barattucci, Giorgia Migliorato, Nicola Berretta, Olaf Riess, Giuseppe Sancesario, Nicola Biagio Mercuri, Francesca Romana Fusco
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 10126
Parkinson’s disease (PD) is a neurodegenerative disease characterized by the accumulation of alpha-synuclein, encoded by the SNCA gene. The main neuropathological hallmark of PD is the degeneration of dopaminergic neurons leading to striatal dopami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be20780519b5e6c8577d64bf26c3a86d
https://doi.org/10.3390/ijms231710126
https://doi.org/10.3390/ijms231710126
Autor:
Mariangela Pierantozzi, Vincenza D'Angelo, Alessandro Stefani, Matteo Spanetta, Salvatore Galati, Laura Clara Grandi, Rocco Cerroni
The history of deep brain stimulation for Parkinson's disease (PD) represented a paradigmatic cross-talk between mammalian disease models and clinical evidence in humans. Fascinating were the results achieved by high frequency stimulation (HFS) into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7444db0f94a16846605df47fb1e8e27e
http://hdl.handle.net/2108/274925
http://hdl.handle.net/2108/274925
Autor:
Vincenza D'Angelo, Giuseppe Sancesario, Francesca Fusco, Mauro Giorgi, I. Saverioni, Stefano Biagioni, Roberto Sorge, Silvia Cardarelli, Antonio Pisani, Nicola Biagio Mercuri, Giuseppina Martella, Emanuela Paldino
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2691, p 2691 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 5
International Journal of Molecular Sciences
Volume 22
Issue 5
We aimed to investigate A2A receptors in the basal ganglia of a DYT1 mouse model of dystonia. A2A was studied in control Tor1a+/+ and Tor1a+/− knock-out mice. A2A expression was assessed by anti-A2A antibody immunofluorescence and Western blotting.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603d7a59da25f1fb36d58987a69762e4
http://hdl.handle.net/2108/287340
http://hdl.handle.net/2108/287340