Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Vincent-Philippe Lavallée"'
Autor:
Marie-Eve Bordeleau, Éric Audemard, Arnaud Métois, Louis Theret, Véronique Lisi, Azer Farah, Jean-François Spinella, Jalila Chagraoui, Ossama Moujaber, Léo Aubert, Banafsheh Khakipoor, Laure Mallinger, Isabel Boivin, Nadine Mayotte, Azadeh Hajmirza, Éric Bonneil, François Béliveau, Sybille Pfammatter, Albert Feghaly, Geneviève Boucher, Patrick Gendron, Pierre Thibault, Frédéric Barabé, Sébastien Lemieux, Guillaume Richard-Carpentier, Josée Hébert, Vincent-Philippe Lavallée, Philippe P. Roux, Guy Sauvageau
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114260- (2024)
Summary: Immunotherapy remains underexploited in acute myeloid leukemia (AML) compared to other hematological malignancies. Currently, gemtuzumab ozogamicin is the only therapeutic antibody approved for this disease. Here, to identify potential targe
Externí odkaz:
https://doaj.org/article/8cf475f1511748f0b536ab3c7b29e97a
Autor:
Leora Witkowski, Laura Palma, Evan Weber, Alexandre Rouette, Loubna Jouan, Andrea Liliam Gomez Corredor, Lara Reichman, Thai-Hoa Tran, Sonia Cellot, William Foulkes, Anne-Marie Laberge, Vincent-Philippe Lavallée, Catherine Goudie
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 100997- (2024)
Externí odkaz:
https://doaj.org/article/ebf1af968d5f4f378976fe7da83e82b5
Autor:
Shirin Lak, Valérie Janelle, Anissa Djedid, Gabrielle Boudreau, Ann Brasey, Véronique Lisi, Ali Smaani, Cédric Carli, Lambert Busque, Vincent-Philippe Lavallée, Jean-Sébastien Delisle
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 230-245 (2022)
Antigen-specific T cell expansion ex vivo followed by adoptive transfer enables targeting of a multitude of microbial and cancer antigens. However, clinical-scale T cell expansion from rare precursors requires repeated stimulation, which may lead to
Externí odkaz:
https://doaj.org/article/69663426dd644361ad6f2f2b985cbce2
Autor:
Yaozong Chen, Jérémie Prévost, Irfan Ullah, Hugo Romero, Veronique Lisi, William D. Tolbert, Jonathan R. Grover, Shilei Ding, Shang Yu Gong, Guillaume Beaudoin-Bussières, Romain Gasser, Mehdi Benlarbi, Dani Vézina, Sai Priya Anand, Debashree Chatterjee, Guillaume Goyette, Michael W. Grunst, Ziwei Yang, Yuxia Bo, Fei Zhou, Kathie Béland, Xiaoyun Bai, Allison R. Zeher, Rick K. Huang, Dung N. Nguyen, Rebekah Sherburn, Di Wu, Grzegorz Piszczek, Bastien Paré, Doreen Matthies, Di Xia, Jonathan Richard, Priti Kumar, Walther Mothes, Marceline Côté, Pradeep D. Uchil, Vincent-Philippe Lavallée, Martin A. Smith, Marzena Pazgier, Elie Haddad, Andrés Finzi
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105783- (2023)
Summary: Neutralizing antibodies (NAbs) hold great promise for clinical interventions against SARS-CoV-2 variants of concern (VOCs). Understanding NAb epitope-dependent antiviral mechanisms is crucial for developing vaccines and therapeutics against
Externí odkaz:
https://doaj.org/article/4347d7b5ecc4456ca4f762f55082f32d
Autor:
Laurence Blain, Christian Watier, Xiaoduan Weng, Andre Masse, Marie-Josée Bédard, Nazila Bettache, Florence Weber, Michele Mahone, Stéphanie Forté, Vincent-Philippe Lavallée, Pierre-Olivier Gaudreau, Michael J. Newmarch, Denis Soulières
Publikováno v:
Diagnostics, Vol 13, Iss 11, p 1873 (2023)
It is believed that fetal hemoglobin (HbF) expression in adults is largely genetically regulated. The increased expression of HbF in pregnancy has been reported in a small number of articles. Different mechanisms have been proposed, but the descripti
Externí odkaz:
https://doaj.org/article/0cb420617487414cb8cf81d1c3a3a9e9
Autor:
Edouard Charlebois, Carine Fillebeen, John Presley, Gael Cagnone, Véronique Lisi, Vincent-Philippe Lavallée, Jean-Sébastien Joyal, Kostas Pantopoulos
Publikováno v:
Blood. 141:271-284
Homeostatic adaptation to systemic iron overload involves transcriptional induction of bone morphogenetic protein 6 (BMP6) in liver sinusoidal endothelial cells (LSECs). BMP6 is then secreted to activate signaling of the iron hormone hepcidin (HAMP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0b884aca24e206dfffb07ce1b742db
https://doi.org/10.1182/blood.2022016987
https://doi.org/10.1182/blood.2022016987
Autor:
Véronique Lisi, Ève Blanchard, Michael Vladovsky, Éric Audemard, Albert Ferghaly, Sébastien Lemieux, Josée Hébert, Guy Sauvageau, Vincent-Philippe Lavallée
Publikováno v:
Blood Advances. 6:5160-5164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902bdab8794ae5fa6eb6892aadec7711
https://doi.org/10.1182/bloodadvances.2022007300
https://doi.org/10.1182/bloodadvances.2022007300
Autor:
Alex Kentsis, Scott A. Armstrong, Jarrod A Marto, Ross Levine, Gayle Pouliot, Guy Sauvageau, Anthony Letai, Martin S. Tallman, Elisabeth M. Paietta, Ari Melnick, Andrei V. Krivtsov, Josée Hébert, Vincent-Philippe Lavallée, Crystal Stutzke, Barbara Spitzer, Conor O'Donnell, Patrick Bhola, Venkatraman Seshan, Mithat Gonen, Elisa de Stanchina, Craig McCarthy, Willie Mark, Peter Romanienko, Scott B. Ficarro, Shehana Gunasekera, Casie Reed, Paolo Cifani, Sumiko Takao, Christina Y. Yim, Richard P. Koche, Eric Still, Fiona C. Brown
Extended methods, supplementary figures and supplementary tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665b2c7724bfc1ebf56cbdf4d423cc22
https://doi.org/10.1158/2159-8290.22532377.v1
https://doi.org/10.1158/2159-8290.22532377.v1
Data S2 from MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia
Autor:
Alex Kentsis, Scott A. Armstrong, Jarrod A Marto, Ross Levine, Gayle Pouliot, Guy Sauvageau, Anthony Letai, Martin S. Tallman, Elisabeth M. Paietta, Ari Melnick, Andrei V. Krivtsov, Josée Hébert, Vincent-Philippe Lavallée, Crystal Stutzke, Barbara Spitzer, Conor O'Donnell, Patrick Bhola, Venkatraman Seshan, Mithat Gonen, Elisa de Stanchina, Craig McCarthy, Willie Mark, Peter Romanienko, Scott B. Ficarro, Shehana Gunasekera, Casie Reed, Paolo Cifani, Sumiko Takao, Christina Y. Yim, Richard P. Koche, Eric Still, Fiona C. Brown
Processed data for S222A+ and S222A- cells by RNA and ATAC sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a290ee3befe02ecdc4208f73225e39
https://doi.org/10.1158/2159-8290.22532386
https://doi.org/10.1158/2159-8290.22532386
Autor:
Guy Sauvageau, Josée Hébert, Anne Marinier, Sébastien Lemieux, Yves Chantigny, Réjean Ruel, Tara MacRae, Jalila Chagraoui, Bernhard Lehnertz, Geneviève Boucher, Irène Baccelli, Jana Krosl, Marie-Eve Bordeleau, Vincent-Philippe Lavallée, Laura Simon
RUNX1 mutations identified in the Leucegene cohort. Position of mutations are indicated using NM_001754 and NM_001001890, coding for RUNX1 proteins of 480 and 453 AA respectively. VAF: variant allele frequency.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43151fe0405ba8e6b952ac63b70a7c58
https://doi.org/10.1158/1078-0432.22462088.v1
https://doi.org/10.1158/1078-0432.22462088.v1