Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Vincent Tano"'
Autor:
Wei Liang Gan, Xi Ren, Vanessa Hui En Ng, Larry Ng, Yangyang Song, Vincent Tano, Jian Han, Omer An, Jinghe Xie, Bryan Y.L. Ng, Daryl Jin Tai Tay, Sze Jing Tang, Haoqing Shen, Shruti Khare, Kelvin Han Chung Chong, Dan Yock Young, Bin Wu, Ramanuj DasGupta, Leilei Chen
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114400- (2024)
Summary: ADAR1-mediated RNA editing establishes immune tolerance to endogenous double-stranded RNA (dsRNA) by preventing its sensing, primarily by MDA5. Although deleting Ifih1 (encoding MDA5) rescues embryonic lethality in ADAR1-deficient mice, they
Externí odkaz:
https://doaj.org/article/c57a92f54d0c4f0eb2c899bfc4bbaec0
Autor:
Vincent Tano, Kagistia Hana Utami, Nur Amirah Binte Mohammad Yusof, Jocelyn Bégin, Willy Wei Li Tan, Mahmoud A. Pouladi, Sarah R. Langley
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104720- (2023)
Summary: Background: In Huntington's disease (HD), a CAG repeat expansion mutation in the Huntingtin (HTT) gene drives a gain-of-function toxicity that disrupts mRNA processing. Although dysregulation of gene splicing has been shown in human HD post-
Externí odkaz:
https://doaj.org/article/0f23e04ff244494bb2dc3c59e327de67
Autor:
Louis T. Dang, Markus Tondl, Man Ho H. Chiu, Jerico Revote, Benedict Paten, Vincent Tano, Alex Tokolyi, Florence Besse, Greg Quaife-Ryan, Helen Cumming, Mark J. Drvodelic, Michael P. Eichenlaub, Jeannette C. Hallab, Julian S. Stolper, Fernando J. Rossello, Marie A. Bogoyevitch, David A. Jans, Hieu T. Nim, Enzo R. Porrello, James E. Hudson, Mirana Ramialison
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background A strong focus of the post-genomic era is mining of the non-coding regulatory genome in order to unravel the function of regulatory elements that coordinate gene expression (Nat 489:57–74, 2012; Nat 507:462–70, 2014; Nat 507:4
Externí odkaz:
https://doaj.org/article/0f1f44ab434441b7b91c6e11217543db
Autor:
Jian Han, Yangyang Song, Jinghe Xie, Vincent Tano, Haoqing Shen, Wei Liang Gan, Ng, Larry, Bryan Yik Loong Ng, Hui En Ng, Vanessa, Xiaohui Sui, Sze Jing Tang, Leilei Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/1/2024, Vol. 121 Issue 40, p1-15, 33p
Autor:
Jian Ruan, Peng Zhao, Jianpeng Sheng, Tiannan Guo, Weijia Fang, Vincent Tano, Sarah Raye Langley, Wenguang Fu, Yixuan Guo, Wei Wu, Juan Lu, Bin Li, Yuzhi Jin, Lingling Huang, Chuan Liu, Rui Sun, Yongfeng Ding, Zheng Zhu, Ming Jiang, Fei Cheng, Xiaoxiang Rong, Xin Li, Yanfang Wang, Xiaomeng Dai, Chanqi Ye, Diyu Chen, Jinzhang Chen, Qiong Li, Xuanwen Bao
Supplementary Figure from Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing–Assisted Multiomics Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ecdb43d73276031b1ea3ddc51f0e6b
https://doi.org/10.1158/2326-6066.22544892.v1
https://doi.org/10.1158/2326-6066.22544892.v1
Autor:
Jian Ruan, Peng Zhao, Jianpeng Sheng, Tiannan Guo, Weijia Fang, Vincent Tano, Sarah Raye Langley, Wenguang Fu, Yixuan Guo, Wei Wu, Juan Lu, Bin Li, Yuzhi Jin, Lingling Huang, Chuan Liu, Rui Sun, Yongfeng Ding, Zheng Zhu, Ming Jiang, Fei Cheng, Xiaoxiang Rong, Xin Li, Yanfang Wang, Xiaomeng Dai, Chanqi Ye, Diyu Chen, Jinzhang Chen, Qiong Li, Xuanwen Bao
Intrahepatic cholangiocarcinoma (ICC) is a relatively rare but highly aggressive tumor type that responds poorly to chemotherapy and immunotherapy. Comprehensive molecular characterization of ICC is essential for the development of novel therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e368ac46d60aebc29895fc92de7d2cd
https://doi.org/10.1158/2326-6066.c.6550770.v1
https://doi.org/10.1158/2326-6066.c.6550770.v1
Autor:
Xuanwen Bao, Qiong Li, Jinzhang Chen, Diyu Chen, Chanqi Ye, Xiaomeng Dai, Yanfang Wang, Xin Li, Xiaoxiang Rong, Fei Cheng, Ming Jiang, Zheng Zhu, Yongfeng Ding, Rui Sun, Chuan Liu, Lingling Huang, Yuzhi Jin, Bin Li, Juan Lu, Wei Wu, Yixuan Guo, Wenguang Fu, Sarah Raye Langley, Vincent Tano, Weijia Fang, Tiannan Guo, Jianpeng Sheng, Peng Zhao, Jian Ruan
Publikováno v:
Cancer Immunology Research. 10:811-828
Intrahepatic cholangiocarcinoma (ICC) is a relatively rare but highly aggressive tumor type that responds poorly to chemotherapy and immunotherapy. Comprehensive molecular characterization of ICC is essential for the development of novel therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e97869377451131bc0c40de124c3fa
https://doi.org/10.1158/2326-6066.cir-21-1101
https://doi.org/10.1158/2326-6066.cir-21-1101
Autor:
Vincent Tano, Kagistia Hana Utami, Nur Amirah Binte Mohammad Yusof, Mahmoud A Pouladi, Sarah R Langley
In Huntington’s disease (HD), a CAG repeat expansion mutation in theHTTgene drives a gain-of-function toxicity that disrupts mRNA processing. Although widespread dysregulation of gene splicing in the striatum has been shown in human HD post-mortem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6163d4daf69cc380060a132be416eab3
https://doi.org/10.1101/2022.11.30.518612
https://doi.org/10.1101/2022.11.30.518612
Autor:
Jianpeng Sheng, Junlei Zhang, Yaxing Zhao, Jinyuan Song, Jianghui Tang, Xun Wang, Yongtao Ji, Jiangchao Wu, Taohong Li, Hui Zhang, Vincent Tano, Sarah Raye Langley, Xueli Bai, Tingbo Liang
Biliary atresia (BA) is a life-threatening neonatal fibro-inflammatory disease characterized by hepatic fibrosis, cirrhosis, and end-stage liver failure. BA is also the most frequent indication of pediatric liver transplantation globally. Despite the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5d7781bf00ecbc36ed8c78599b92cd9
https://doi.org/10.1101/2022.03.11.483921
https://doi.org/10.1101/2022.03.11.483921
Autor:
Anna L. Leichter, Carmel M. O’Brien, David R. Powell, Hun S. Chy, Jahnvi Pflueger, Ziyi Huang, Guizhi Sun, Amander T. Clark, Joseph Chen, Jacob M. Paynter, Andrew L. Laslett, Xin Yi Choo, Sam Buckberry, Christian M. Nefzger, Haroon Naeem, Jaber Firas, Pratibha Tripathi, John F. Ouyang, Vincent Tano, Daniela S. Valdes, Jia Ping Tan, Susan K. Nilsson, Michael R. Larcombe, Daniel Poppe, Di Chen, Fernando J. Rossello, Jan Schröder, Xiaodong Liu, Alexandra Grubman, Anja S Knaupp, Owen J. L. Rackham, Jose M. Polo, Ryan Lister, Yu Bo Yang Sun, Luciano G. Martelotto, Laurent David, William A. Pastor, Kathryn C. Davidson, Partha Pratim Das
Publikováno v:
Nature. 586:101-107
The reprogramming of human somatic cells to primed or naive induced pluripotent stem cells recapitulates the stages of early embryonic development 1–6. The molecular mechanism that underpins these reprogramming processes remains largely unexplored,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566b994293c0280e6af5e95a5db265f0
https://doi.org/10.1038/s41586-020-2734-6
https://doi.org/10.1038/s41586-020-2734-6