Výsledky vyhledávání - "Vincent Sahi"

Akademický článek

2549 Characterizing the expression kinetics of HIV-1 envelope protein

Autor: Djin-Ye Oh, Lihong Liu, Benjamin Trinité, En-Wei Hu-Van Wright, Vincent Sahi, Yaoxing Huang, David N. Levy, David D. Ho

Publikováno v: Journal of Clinical and Translational Science, Vol 2, Pp 7-7 (2018)

OBJECTIVES/SPECIFIC AIMS: Characterize the expression kinetics of HIV-1 Envelope and their relationship to virus production at the cellular level. METHODS/STUDY POPULATION: In vitro and ex vivo laboratory analyses. RESULTS/ANTICIPATED RESULTS: Initia

Externí odkaz: https://doaj.org/article/3cbf241f8b244781aba5d36e5579b660

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CRISPR-based gene knockout screens reveal deubiquitinases involved in HIV-1 latency in two Jurkat cell models

Autor: Pengfei Wang, Manxue Jia, David D. Ho, Anurag Rathore, Sho Iketani, Vincent Sahi

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports

The major barrier to a HIV-1 cure is the persistence of latent genomes despite treatment with antiretrovirals. To investigate host factors which promote HIV-1 latency, we conducted a genome-wide functional knockout screen using CRISPR-Cas9 in a HIV-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b0a5f1590cba4c9de82e843ced7aee
http://link.springer.com/article/10.1038/s41598-020-62375-3

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Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria

Autor: Elizabeth Nardin, Min Zhang, Victor Nussenzweig, Ramses Ayala, Vincent Sahi, Gabriel M. Gutierrez, Robert Mitchell, Xiangming Li, Amy R. Noe, Tiffany Tsao, Raquel Tayar Nogueira, Moriya Tsuji, Ruth S. Nussenzweig, Jordana Grazziela Coelho-dos-Reis, Jing Huang, James M. Wilson

Publikováno v: Journal of Immunological Methods. 427:42-50

In this study, we developed human immune system (HIS) mice that possess functional human CD4+ T cells and B cells, named HIS-CD4/B mice. HIS-CD4/B mice were generated by first introducing HLA class II genes, including DR1 and DR4, along with genes en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa93b67b6794589101836ab166d96301
https://doi.org/10.1016/j.jim.2015.09.005

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Human IgG repertoire of malaria antigen-immunized human immune system (HIS) mice

Autor: Raquel Tayar Nogueira, Vincent Sahi, Jing Huang, Moriya Tsuji

Publikováno v: Immunology letters. 188

Humanized mouse models present an important tool for preclinical evaluation of new vaccines and therapeutics. Here we show the human variable repertoire of antibody sequences cloned from a previously described human immune system (HIS) mouse model th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fb233af0a500135d1e76e93e2ada72
https://pubmed.ncbi.nlm.nih.gov/28610800

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2549 Characterizing the expression kinetics of HIV-1 envelope protein

Autor: En-Wei Hu-Van Wright, Lihong Liu, Benjamin Trinité, Djin-Ye Oh, David D. Ho, Yaoxing Huang, Vincent Sahi, David N. Levy

Publikováno v: Journal of Clinical and Translational Science

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f66a2bfc342886581f1f9c1747e83e
https://doi.org/10.1017/cts.2018.54

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A randomized open-label study of 3- versus 5-drug combination antiretroviral therapy in newly HIV-1-infected individuals

Autor: Kristina Rodriguez, Teresa H. Evering, Nicole Prada, Hiroshi Mohri, Vincent Sahi, Sarah Palmer, Martin Markowitz, Marina Caskey, Donald Garmon, Melissa La Mar

Publikováno v: Journal of acquired immune deficiency syndromes (1999). 66(2)

BACKGROUND To understand whether combination antiretroviral therapy (cART) has been optimized, we asked whether 3-drug protease inhibitor (PI)-based cART intensified with raltegravir and maraviroc and initiated during early infection would improve ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20145fc6bc9a744baebf97b7778d404
https://pubmed.ncbi.nlm.nih.gov/24457632

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Epidermal browning of saguaro cacti (Carnegiea gigantea): Relative health and rates of surficial injuries of a population

Autor: Sonja Ghersini, Lance S. Evans, Vincent Sahi

Publikováno v: Environmental and Experimental Botany. 35:557-562

Epidermal browning appears to be occurring on virtually all medium and older-aged saguaros [ Carnegiea gigantea (Engelm.) Britt. and Rose] throughout the Sonoran Desert. The purpose of this research was to determine if a population of 253 saguaros co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a82dd6bbb5b02a39865b45353ea165c7
https://doi.org/10.1016/0098-8472(95)00020-8

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Targeted co-delivery of tumor antigen and alpha-galactosylceramide to CD141(+) dendritic cells induces a potent tumor antigen-specific human CD8(+) T cell response in human immune system mice

Autor: François Trottein, Reem Ghinnagow, Sho Iketani, Daphnée Soulard, Jing Huang, Sean Mackay, Jing Zhou, Yukiko Tsuji, Moriya Tsuji, Patrick Paczkowski, Luis J. Cruz, Toshiyuki Seki

Publikováno v: Frontiers in Immunology, 11. FRONTIERS MEDIA SA
Frontiers in Immunology
Frontiers in Immunology, 2020, 11, pp.2043. ⟨10.3389/fimmu.2020.02043⟩
Frontiers in Immunology, Frontiers, 2020, 11, pp.2043. ⟨10.3389/fimmu.2020.02043⟩
Frontiers in Immunology, Vol 11 (2020)

Active co-delivery of tumor antigens (Ag) and alpha-galactosylceramide (alpha-GalCer), a potent agonist for invariant Natural Killer T (iNKT) cells, to cross-priming CD8 alpha(+) dendritic cells (DCs) was previously shown to promote strong anti-tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da61d6a3cbe282ae349622d7862a40ce
http://hdl.handle.net/1887/3184215

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