Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vincent S. Hau"'
Publikováno v:
Ophthalmology and Therapy
Advanced or end-stage age-related macular degeneration (AMD) results in significant visual impairment and a substantially reduced quality of life for patients. Therapeutic options for people with bilateral moderate or profound vision loss caused by e
Autor:
David R. Archer, Mingshen Wang, Vincent S. Hau, Brian J. Ciliax, Harish C. Joshi, Erwin G. Van Meir, Bruce H. Wainer, Jaren W. Landen, Thomas P. Davis, Johnathan D. Glass
Publikováno v:
Clinical Cancer Research. 10:5187-5201
The opium alkaloid noscapine is a commonly used antitussive agent available in Europe, Asia, and South America. Although the mechanism by which it suppresses coughing is currently unknown, it is presumed to involve the central nervous system. In addi
Publikováno v:
Brain Research. 1018:257-264
This study investigated the potential clinical implications of lambda-carrageenan-induced inflammatory pain on brain uptake of a commonly used analgesic, codeine, in relation to the fundamental properties of the blood-brain barrier (BBB) correlated t
Autor:
Chris R. Campos, Richard D. Egleton, Jason D. Huber, Thomas P. Davis, Lindsay K. Borg, Vincent S. Hau
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 283(4)
In this study, we examined the effect of λ-carrageenan-induced inflammatory pain on the functional and structural properties of the rat blood-brain barrier (BBB) over a 72-h time period. Systemic inflammation was induced by an intraplantar injection
Autor:
Christopher R. Campos, Vincent S. Hau, Andrzej W. Lipkowski, Thomas P. Davis, Jason D. Huber, Aleksandra Misicka
Publikováno v:
Journal of pharmaceutical sciences. 91(10)
Endomorphin II (ENDII), an endogenous ligand for the mu-opioid receptor, was investigated as a possible analgesic with fewer side effects than morphine. To improve CNS entry of END II, structural modification was also examined to determine whether Pr
Autor:
Jason D. Huber, Thomas P. Davis, Karen S. Mark, Chris R. Campos, Vincent S. Hau, Rachel C. Brown
Publikováno v:
European journal of pharmacology. 450(3)
We investigated three inflammatory agents to establish if these substances elicit a direct effect on the functional and structural integrity of the blood-brain barrier. Cellular cytotoxicity and paracellular permeability were assessed in vitro using
Publikováno v:
Biological psychology. 49(3)
Jamner, L.D., Schwartz, G.E., 1986, Psychosom. Med. 48, 211–223, have proposed that repressive and defensive coping are associated with greater central endogenous opioid activity. They reasoned that high-defensive (HD) participants’ attenuated di
Elevation of plasma beta-endorphin levels of shy elderly in response to novel laboratory experiences
Publikováno v:
Behavioral medicine (Washington, D.C.). 22(4)
Heightened psychophysiological reactivity to the novel or unfamiliar is a leading characteristic of sky or behaviorally inhibited individuals. To assess one aspect of the physiological stress response in shyness, the authors compared the morning plas
Autor:
Cheryl Ritenbaugh, Vincent S. Hau, Gary E. Schwartz, Thomas P. Davis, Richard R. Bootzin, Kathleen A. Johnson, Iris R. Bell
Publikováno v:
Biological psychiatry. 40(2)
This study examined plasma beta-endorphin as a marker of the physiological stress response in community elderly who were either high ( n = 15) or low ( n = 15) in self-rated frequency of illness from environmental chemical odors. Individuals who repo