Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vincent R. Torti"'
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 106:511-522
4-[3-(2-Nitro-1-imidazolyl)-propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a 2-nitroimidazole-based hypoxia-selective cytotoxin has been shown to target hypoxic regions of solid tumours. The present study is one of several pre-clinical toxico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87c3d8365a8000cdcf88027295d4fa15
https://doi.org/10.1111/j.1742-7843.2009.00532.x
https://doi.org/10.1111/j.1742-7843.2009.00532.x
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 106:497-504
In pre-clinical studies, 4-[3-(2-nitro-1-imidazolyl)-propylamino]-7-chloroquinoline hydrochloride (NLCQ-1, NSC 709257) is a weak DNA-intercalating, hypoxia-selective cytotoxin with a promising profile as an adjuvant to radio/chemotherapy and it is ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f873205e3dfa3d439f7c04645c4a5bf6
https://doi.org/10.1111/j.1742-7843.2009.00530.x
https://doi.org/10.1111/j.1742-7843.2009.00530.x
Autor:
Vincent R. Torti, Clifford A. Rinehart
Publikováno v:
Molecular Carcinogenesis. 18:187-192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea97d1960ba03775345ce46989210746
https://doi.org/10.1002/(sici)1098-2744(199704)18:4<187::aid-mc1>3.0.co
https://doi.org/10.1002/(sici)1098-2744(199704)18:4<187::aid-mc1>3.0.co
Publikováno v:
Basicclinical pharmacologytoxicology. 106(6)
4-[3-(2-Nitro-1-imidazolyl)-propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a 2-nitroimidazole-based hypoxia-selective cytotoxin has been shown to target hypoxic regions of solid tumours. The present study is one of several pre-clinical toxico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::847287b06252484907a311ac78a02bef
https://pubmed.ncbi.nlm.nih.gov/20074266
https://pubmed.ncbi.nlm.nih.gov/20074266
Publikováno v:
Basicclinical pharmacologytoxicology. 106(6)
In pre-clinical studies, 4-[3-(2-nitro-1-imidazolyl)-propylamino]-7-chloroquinoline hydrochloride (NLCQ-1, NSC 709257) is a weak DNA-intercalating, hypoxia-selective cytotoxin with a promising profile as an adjuvant to radio/chemotherapy and it is ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::545c2eed0fdb4c5a3023020b89c65213
https://pubmed.ncbi.nlm.nih.gov/20074267
https://pubmed.ncbi.nlm.nih.gov/20074267
Publikováno v:
Mutation research. 520(1-2)
Bromodichloromethane (BDCM) is commonly present in trace amounts in drinking water as a disinfection by-product. BDCM has been shown to be carcinogenic in mice and rats when given by gavage at relatively high doses. Genotoxic activity as well as indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c22952d9d5872e41625dd4b7f22207
https://pubmed.ncbi.nlm.nih.gov/12297157
https://pubmed.ncbi.nlm.nih.gov/12297157
Autor:
Marianne W. Marshall, Byron E. Butterworth, Vincent R. Torti, Alison J. Cobb, Jeffrey I. Everitt, Gary A. Boorman
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 64(2)
Bromodichloromethane (BDCM) is a common municipal drinking water disinfection by-product, resulting in widespread trace human exposure via ingestion and inhalation. The present studies were designed to define organ-specific, BDCM-induced toxicity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90093b2f6f96c562be4b81725f363af1
https://pubmed.ncbi.nlm.nih.gov/11719710
https://pubmed.ncbi.nlm.nih.gov/11719710
Publikováno v:
Experimental cell research. 248(2)
The causes of the age-related increase in cancer rates are poorly understood. One cause could be age-related changes in the stromal/epithelial cell interactions that facilitate tumorigenesis. We tested the hypothesis that aging of human endometrial s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5440e494769c0cbe46eeba6af4dd7fa5
https://pubmed.ncbi.nlm.nih.gov/10222152
https://pubmed.ncbi.nlm.nih.gov/10222152