Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vincent R. Graziano"'
Publikováno v:
Viruses, Vol 11, Iss 6, p 495 (2019)
Human norovirus is a major human pathogen causing the majority of cases of viral gastroenteritis globally. Viral entry is the first step of the viral life cycle and is a significant determinant of cell tropism, host range, immune interactions, and pa
Externí odkaz:
https://doaj.org/article/b22324fbe64e4b338fb9195f7a32c485
Autor:
Jin Wei, Mia Madel Alfajaro, Wesley L Cai, Vincent R Graziano, Madison S Strine, Renata B Filler, Scott B Biering, Sylvia A Sarnik, Sonam Patel, Bridget L Menasche, Susan R Compton, Silvana Konermann, Patrick D Hsu, Robert C Orchard, Qin Yan, Craig B Wilen
Publikováno v:
PLoS Pathogens, Vol 19, Iss 7, p e1011351 (2023)
Identification of host determinants of coronavirus infection informs mechanisms of pathogenesis and may provide novel therapeutic targets. Here, we demonstrate that the histone demethylase KDM6A promotes infection of diverse coronaviruses, including
Externí odkaz:
https://doaj.org/article/96107a75fb7e477fb76c01fbddef0ecf
Autor:
Madison S. Strine, Mia Madel Alfajaro, Vincent R. Graziano, Jaewon Song, Leon L. Hsieh, Ryan Hill, Jun Guo, Kelli L. VanDussen, Robert C. Orchard, Megan T. Baldridge, Sanghyun Lee, Craig B. Wilen
Publikováno v:
Cell reports. 41(6)
Murine norovirus (MNoV) is a model for human norovirus and for interrogating mechanisms of viral tropism and persistence. We previously demonstrated that the persistent strain MNoV
Autor:
Shu Zhu, Craig B. Wilen, Philip M Frasse, Stefan T. Peterson, Christiane E. Wobus, Abel Hernandez, Matthew Phillips, Emily W. Helm, Megan T. Baldridge, Vincent R. Graziano, Katrina R. Grau, Holly Turula, Drake T. Philip, Stephanie M. Karst
Publikováno v:
Nature Microbiology. 5:84-92
Evidence has accumulated to demonstrate that the intestinal microbiota enhances mammalian enteric virus infections1. For example, we and others previously reported that commensal bacteria stimulate acute and persistent murine norovirus infections2-4.
Autor:
Jin Wei, Vincent R. Graziano, Renata B. Filler, Sanghyun Lee, Craig B. Wilen, Mia Madel Alfajaro, Madison S. Strine, Timothy J. Nice, Cameron O. Schmitz, Megan T. Baldridge, Robert C. Orchard, Leon L. Hsieh
Publikováno v:
J Virol
Noroviruses are a leading cause of gastrointestinal infection in humans and mice. Understanding human norovirus (HuNoV) cell tropism has important implications for our understanding of viral pathogenesis. Murine norovirus (MNoV) is extensively used a
Autor:
Alexa N. Roth, Lawrence A. Schriefer, Cassandra E Thompson, Rachel Rodgers, Megan T. Baldridge, Jonathan J. Miner, Yuhao Li, Ebrahim Hassan, Stephanie M. Karst, Forrest C. Walker, Dylan Lawrence, Carla Blum-Johnston, Sanghyun Lee, Vincent R. Graziano, Broc T. McCune, Gowri Kalugotla, Larissa Lushniak, Stefan T. Peterson, Craig B. Wilen, Timothy J. Nice
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 3, p e1009402 (2021)
PLoS Pathogens, Vol 17, Iss 3, p e1009402 (2021)
Interferons (IFNs) are key controllers of viral replication, with intact IFN responses suppressing virus growth and spread. Using the murine norovirus (MNoV) system, we show that IFNs exert selective pressure to limit the pathogenic evolutionary pote
Autor:
Madison S. Strine, Benhur Lee, Craig B. Wilen, Kasopefoluwa Y. Oguntuyo, Ruth E Hanna, Jennifer S. Chen, Katerina Politi, Fernando J. de Miguel, David van Dijk, Shang-Min Zhang, Madeleine C. Mankowski, Brett D. Lindenbach, Laura Abriola, Peter C DeWeirdt, John G. Doench, Mia Madel Alfajaro, Matthew D. Simon, Renata B. Filler, Victor Gasque, Vincent R. Graziano, Cameron O. Schmitz, Yulia V. Surovtseva, William J. Lu-Culligan, Huacui Chen, Jin Wei, Qin Yan, Robert C. Orchard
Publikováno v:
Cell
bioRxiv
article-version (status) pre
article-version (number) 1
bioRxiv
article-version (status) pre
article-version (number) 1
Identification of host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding of coronavirus disease 2019 (COVID-19) pathogenesis. Here we performed
Autor:
Madison S. Strine, Leon L. Hsieh, Mia Madel Alfajaro, Vincent R. Graziano, Jin Wei, Robert C. Orchard, Craig B. Wilen, Megan T. Baldridge, Sanghyun Lee, Cameron O. Schmitz, Renata B. Filler, Timothy J. Nice
Noroviruses are a leading cause of gastrointestinal infection in humans and mice. Understanding human norovirus (HuNoV) cell tropism has important implications for our understanding of viral pathogenesis. Murine norovirus (MNoV) is extensively used a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f9672591f3e836d8d9566ddfaade0a4
https://doi.org/10.1101/2020.08.19.258467
https://doi.org/10.1101/2020.08.19.258467
Autor:
Christiane E. Wobus, Abimbola O. Kolawole, Leon L. Hsieh, Megan T. Baldridge, Madison S. Simões, Craig B. Wilen, Elizabeth A. Kennedy, Jin Wei, Lisa C. Lindesmith, Forrest C. Walker, Khalil Ettayebi, Ebrahim Hassan, Renata B. Filler, Ralph S. Baric, Robert C. Orchard, Vincent R. Graziano, Mary K. Estes
Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. Viral receptor utilization is a major determinant of cell tropism, host range, and pathogenesis. Thebona fidereceptor for HNoV is unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03e6df9de67178a3f1b5a6ec57d9f81
Autor:
Long Yang, Vincent R Graziano, Anthony T. Vella, Penghua Wang, Tingting Geng, Harshada Ketkar, Andrew G. Harrison
Publikováno v:
J Immunol
Type I/III interferons (IFN) induce expression of hundreds of interferon stimulated genes (ISGs) through the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway to combat viral infections. Although JAK/STAT signaling is