Involving the next generation of cardiovascular surgeons

Autor: Vincent Q. Sier, MSc, Joris J. Blok, MD, PhD, Ferdi Akca, MD, PhD, Jesper Hjortnaes, MD, PhD, Joost R. van der Vorst, MD, PhD

Publikováno v: JTCVS Open, Vol 20, Iss , Pp 210- (2024)

Externí odkaz: https://doaj.org/article/23514947545b422a8c139f6a0cd7410e

Interfering in the ALK1 Pathway Results in Macrophage-Driven Outward Remodeling of Murine Vein Grafts

Autor: Alwin de Jong, Vincent Q. Sier, Hendrika A. B. Peters, Natalia K. M. Schilder, J. Wouter Jukema, Marie José T. H. Goumans, Paul H. A. Quax, Margreet R. de Vries

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 8 (2022)

AimsVein grafts are frequently used to bypass coronary artery occlusions. Unfortunately, vein graft disease (VGD) causes impaired patency rates. ALK1 mediates signaling by TGF-β via TGFβR2 or BMP9/10 via BMPR2, which is an important pathway in fibr

Externí odkaz: https://doaj.org/article/e151280a58d144afbb3c54ab231778f6

A multimodal molecular imaging approach targeting urokinase plasminogen activator receptor for the diagnosis, resection and surveillance of urothelial cell carcinoma

Autor: Massimo Resnati, Victor M Baart, Rob C.M. Pelger, Timo Schomann, Peter J. K. Kuppen, Maaike H. van der Mark, Vincent Q. Sier, Hugo de Jonge, Gabriel van der Pluijm, Marion M. Deken, Luisa Iamele, Shadhvi S. Bhairosingh, Alexander L. Vahrmeijer, Andrew P. Mazar, Cornelis F. M. Sier, Geertje van der Horst

Publikováno v: European Journal of Cancer
European Journal of Cancer, 146, 11-20. ELSEVIER SCI LTD

With a 5-year recurrence rate of 30-78%, urothelial cell carcinoma (UCC) rates amongst the highest of all solid malignancies. Consequently, after transurethral resection, patients are subjugated to life-long endoscopic surveillance. A multimodal near

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89deef8a90f2fda9ae57dee4c5047e85
https://doi.org/10.1016/j.ejca.2021.01.001

Cell-Based Tracers as Trojan Horses for Image-Guided Surgery

Autor: Munitta Muthana, Margreet R. de Vries, Vincent Q Sier, Lioe-Fee de Geus-Oei, Cornelis van Kooten, Alexander L. Vahrmeijer, Luis J. Cruz, Frauke Alves, Cornelis F. M. Sier, Joost R. van der Vorst, Valerie Ferreira

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 755, p 755 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 22(2). MDPI

Surgeons rely almost completely on their own vision and palpation to recognize affected tissues during surgery. Consequently, they are often unable to distinguish between different cells and tissue types. This makes accurate and complete resection cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cc9ae9cb9e397924730f50fe7dc74d
https://www.mdpi.com/1422-0067/22/2/755

Preclinical evaluation of EpCAM-binding designed ankyrin repeat proteins (DARPins) as targeting moieties for bimodal near-infrared fluorescence and photoacoustic imaging of cancer.

Autor: Houvast, Ruben D.¹ (AUTHOR) R.D.Houvast@lumc.nl, Badr, Nada¹ (AUTHOR), March, Taryn² (AUTHOR), de Muynck, Lysanne D. A. N.¹ (AUTHOR), Sier, Vincent Q.¹ (AUTHOR), Schomann, Timo^1,3 (AUTHOR), Bhairosingh, Shadhvi¹ (AUTHOR), Baart, Victor M.¹ (AUTHOR), Peeters, Judith A. H. M.¹ (AUTHOR), van Westen, Gerard J. P.⁴ (AUTHOR), Plückthun, Andreas⁵ (AUTHOR), Burggraaf, Jacobus^1,6 (AUTHOR), Kuppen, Peter J. K.¹ (AUTHOR), Vahrmeijer, Alexander L.¹ (AUTHOR), Sier, Cornelis F. M.¹ (AUTHOR)

Publikováno v: European Journal of Nuclear Medicine & Molecular Imaging. Jul2024, Vol. 51 Issue 8, p2179-2192. 14p.