Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Vincent Philippe Lavallée"'
Autor:
Damien Maggiorani, Oanh Le, Véronique Lisi, Séverine Landais, Gaël Moquin-Beaudry, Vincent Philippe Lavallée, Hélène Decaluwe, Christian Beauséjour
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The potential of immune checkpoint inhibitors (ICI) may be limited in situations where immune cell fitness is impaired. Here, we show that the efficacy of cancer immunotherapies is compromised by the accumulation of senescent cells in mice a
Externí odkaz:
https://doaj.org/article/6176530a4d9a475d942f002aa1f6fc5f
Autor:
Nicolas Poirier, Elie Haddad, Michel Duval, Valérie Paquin, Séverine Leclerc, Véronique Lisi, Carolina Marmolejo, Hicham Affia, Paulo Cordeiro, Yves Théorêt, Gregor Andelfinger, Vincent Philippe Lavallée, Sabine Herblot
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Allogeneic hematopoietic stem cell transplantation (HSCT) remains the standard of care for chemotherapy-refractory leukemia patients, but cure rates are still dismal. To prevent leukemia relapse following HSCT, we aim to improve the early
Externí odkaz:
https://doaj.org/article/f0f0716f6dc24b4b8ba472b368e8d196
Autor:
Shirin Lak, Valérie Janelle, Anissa Djedid, Gabrielle Boudreau, Ann Brasey, Véronique Lisi, Ali Smaani, Cédric Carli, Lambert Busque, Vincent-Philippe Lavallée, Jean-Sébastien Delisle
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 230-245 (2022)
Antigen-specific T cell expansion ex vivo followed by adoptive transfer enables targeting of a multitude of microbial and cancer antigens. However, clinical-scale T cell expansion from rare precursors requires repeated stimulation, which may lead to
Externí odkaz:
https://doaj.org/article/69663426dd644361ad6f2f2b985cbce2
Autor:
Yaozong Chen, Jérémie Prévost, Irfan Ullah, Hugo Romero, Veronique Lisi, William D. Tolbert, Jonathan R. Grover, Shilei Ding, Shang Yu Gong, Guillaume Beaudoin-Bussières, Romain Gasser, Mehdi Benlarbi, Dani Vézina, Sai Priya Anand, Debashree Chatterjee, Guillaume Goyette, Michael W. Grunst, Ziwei Yang, Yuxia Bo, Fei Zhou, Kathie Béland, Xiaoyun Bai, Allison R. Zeher, Rick K. Huang, Dung N. Nguyen, Rebekah Sherburn, Di Wu, Grzegorz Piszczek, Bastien Paré, Doreen Matthies, Di Xia, Jonathan Richard, Priti Kumar, Walther Mothes, Marceline Côté, Pradeep D. Uchil, Vincent-Philippe Lavallée, Martin A. Smith, Marzena Pazgier, Elie Haddad, Andrés Finzi
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105783- (2023)
Summary: Neutralizing antibodies (NAbs) hold great promise for clinical interventions against SARS-CoV-2 variants of concern (VOCs). Understanding NAb epitope-dependent antiviral mechanisms is crucial for developing vaccines and therapeutics against
Externí odkaz:
https://doaj.org/article/4347d7b5ecc4456ca4f762f55082f32d
Autor:
Laurence Blain, Christian Watier, Xiaoduan Weng, Andre Masse, Marie-Josée Bédard, Nazila Bettache, Florence Weber, Michele Mahone, Stéphanie Forté, Vincent-Philippe Lavallée, Pierre-Olivier Gaudreau, Michael J. Newmarch, Denis Soulières
Publikováno v:
Diagnostics, Vol 13, Iss 11, p 1873 (2023)
It is believed that fetal hemoglobin (HbF) expression in adults is largely genetically regulated. The increased expression of HbF in pregnancy has been reported in a small number of articles. Different mechanisms have been proposed, but the descripti
Externí odkaz:
https://doaj.org/article/0cb420617487414cb8cf81d1c3a3a9e9
Autor:
Edouard Charlebois, Carine Fillebeen, John Presley, Gael Cagnone, Véronique Lisi, Vincent-Philippe Lavallée, Jean-Sébastien Joyal, Kostas Pantopoulos
Publikováno v:
Blood. 141:271-284
Homeostatic adaptation to systemic iron overload involves transcriptional induction of bone morphogenetic protein 6 (BMP6) in liver sinusoidal endothelial cells (LSECs). BMP6 is then secreted to activate signaling of the iron hormone hepcidin (HAMP)
Autor:
Véronique Lisi, Ève Blanchard, Michael Vladovsky, Éric Audemard, Albert Ferghaly, Sébastien Lemieux, Josée Hébert, Guy Sauvageau, Vincent-Philippe Lavallée
Publikováno v:
Blood Advances. 6:5160-5164
Autor:
Ana Rio-Machin, Findlay Bewicke-Copley, Jiexin Zheng, Pedro Casado Izquierdo, Juho J. Miettinen, Naeem Khan, Jonas Demeulemeester, Szilvia Krizsán, Christopher Middleton, Sam Benkwitz-Bedford, Joseph Saad, Amaia Vilas-Zornoza, Teresa Ezponda, William Grey, Vincent-Philippe Lavallée, Alexis Nolin-Lapalme, Farideh Miraki-Moud, Janet Matthews, Marianne Grantham, Ryan J Colm, Jonathan Bond, Doriana Di Bella, Krister Wennerberg, Alun Parsons, Andy G.X. Zeng, Hannah Armes, Karina Close, Fadimana Kaya, Kevin Rouault-Pierre, John G. Gribben, Felipe Prosper, James Cavenagh, John E. Dick, Sylvie D Freeman, Peter Van Loo, Csaba Bödör, Guy Sauvageau, Kimmo Porkka, Caroline A. Heckman, Jun Wang, Jean-Baptiste Cazier, David Taussig, Dominique Bonnet, Pedro Cutillas, Jude Fitzgibbon
Publikováno v:
Blood. 140:1030-1032
Autor:
Alex Kentsis, Scott A. Armstrong, Jarrod A Marto, Ross Levine, Gayle Pouliot, Guy Sauvageau, Anthony Letai, Martin S. Tallman, Elisabeth M. Paietta, Ari Melnick, Andrei V. Krivtsov, Josée Hébert, Vincent-Philippe Lavallée, Crystal Stutzke, Barbara Spitzer, Conor O'Donnell, Patrick Bhola, Venkatraman Seshan, Mithat Gonen, Elisa de Stanchina, Craig McCarthy, Willie Mark, Peter Romanienko, Scott B. Ficarro, Shehana Gunasekera, Casie Reed, Paolo Cifani, Sumiko Takao, Christina Y. Yim, Richard P. Koche, Eric Still, Fiona C. Brown
Extended methods, supplementary figures and supplementary tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665b2c7724bfc1ebf56cbdf4d423cc22
https://doi.org/10.1158/2159-8290.22532377.v1
https://doi.org/10.1158/2159-8290.22532377.v1
Data S4 from MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia
Autor:
Alex Kentsis, Scott A. Armstrong, Jarrod A Marto, Ross Levine, Gayle Pouliot, Guy Sauvageau, Anthony Letai, Martin S. Tallman, Elisabeth M. Paietta, Ari Melnick, Andrei V. Krivtsov, Josée Hébert, Vincent-Philippe Lavallée, Crystal Stutzke, Barbara Spitzer, Conor O'Donnell, Patrick Bhola, Venkatraman Seshan, Mithat Gonen, Elisa de Stanchina, Craig McCarthy, Willie Mark, Peter Romanienko, Scott B. Ficarro, Shehana Gunasekera, Casie Reed, Paolo Cifani, Sumiko Takao, Christina Y. Yim, Richard P. Koche, Eric Still, Fiona C. Brown
Processed data for MRT199665 and DMSO treated OCI-AML2 cells by RNA sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2bcfb03940ebc2200b2e48e934f24d
https://doi.org/10.1158/2159-8290.22532380
https://doi.org/10.1158/2159-8290.22532380